Article ; Online: Epidemiological characteristics of the first 100 cases of coronavirus disease 2019 (COVID-19) in Hong Kong Special Administrative Region, China, a city with a stringent containment policy.
International journal of epidemiology
2020 Volume 49, Issue 4, Page(s) 1096–1105
Abstract: ... disease 2019 (COVID-19) outbreak. Stringent border control together with aggressive case finding ... stringent containment policies minimized the importation and transmission of COVID-19 in HK. ... Background: Hong Kong (HK) is a densely populated city near the epicentre of the coronavirus ...
| Abstract | Background: Hong Kong (HK) is a densely populated city near the epicentre of the coronavirus disease 2019 (COVID-19) outbreak. Stringent border control together with aggressive case finding, contact tracing, social distancing and quarantine measures were implemented to halt the importation and spread of the virus. Methods: We performed an epidemiological study using government information covering the first 100 confirmed cases to examine the epidemic curve, incidence, clusters, reproduction number (Rt), incubation period and time to containment. Results: A total of 93 of the 100 cases were HK residents (6 infected in Mainland China, 10 on the Diamond Princess Cruise). Seven were visitors infected in Mainland China before entering HK. The majority (76%) were aged ≥45 years, and the incidence increased with age (P < 0.001). Escalation of border control measures correlated with a decrease in the proportion (62.5% to 0%) of cases imported from Mainland China, and a reduction in Rt (1.07 to 0.75). The median incubation period was 4.2 days [95% confidence interval (CI), 4.0-4.5; 5th and 95th percentiles: 1.3 and 14.0). Most clusters with identifiable epidemiological links were households involving 2-4 people. Three medium-spreading events were identified: two from New Year gatherings (6-11 people), and another from environmental contamination of a worship hall (12 people). Despite intensified contact tracing, containment was delayed in 78.9% of cases (mean = 5.96 days, range = 0-24 days). An unusual transmission in a multi-storey building via faulty toilet plumbing was suspected with >100 residents evacuated overnight. Our analysis indicated that faulty plumbing was unlikely to be the source of this transmission. Conclusion: Timely stringent containment policies minimized the importation and transmission of COVID-19 in HK. |
|---|---|
| MeSH term(s) | Adult ; Aged ; Betacoronavirus ; COVID-19 ; China/epidemiology ; Coronavirus ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Disease Outbreaks/prevention & control ; Female ; Hong Kong/epidemiology ; Humans ; Incidence ; Male ; Middle Aged ; Pandemics/prevention & control ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; Psychological Distance ; Quarantine ; SARS-CoV-2 |
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-06-29 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 187909-1 |
| ISSN | 1464-3685 ; 0300-5771 |
| ISSN (online) | 1464-3685 |
| ISSN | 0300-5771 |
| DOI | 10.1093/ije/dyaa106 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
| Zs.A 893: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.