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  1. Article: Calcium phosphate materials in restorative dentistry: a review.

    LeGeros, R Z

    Advances in dental research

    1988  Volume 2, Issue 1, Page(s) 164–180

    MeSH term(s) Calcium Phosphates ; Composite Resins ; Dental Cements ; Dental Materials ; Prostheses and Implants
    Chemical Substances Calcium Phosphates ; Composite Resins ; Dental Cements ; Dental Materials ; alpha-tricalcium phosphate ; tetracalcium phosphate ; calcium phosphate, monobasic, anhydrous (701EKV9RMN) ; calcium phosphate (97Z1WI3NDX) ; calcium phosphate, dibasic, anhydrous (L11K75P92J)
    Language English
    Publishing date 1988-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 639406-1
    ISSN 1544-0737 ; 0895-9374
    ISSN (online) 1544-0737
    ISSN 0895-9374
    DOI 10.1177/08959374880020011101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Advances and challenges in regenerative dentistry: A systematic review of calcium phosphate and silicate-based materials on human dental pulp stem cells.

    Christie, B / Musri, N / Djustiana, N / Takarini, V / Tuygunov, N / Zakaria, M N / Cahyanto, A

    Materials today. Bio

    2023  Volume 23, Page(s) 100815

    Abstract: ... of restorative materials. Regenerative dentistry, utilizing stem cells and bioactive materials, offers ... materials like calcium phosphate (CaP) and silicate-based materials have shown potential for dental tissue ... regeneration. This systematic review aims to investigate the effects of CaP and silicate-based materials ...

    Abstract Conventional dentistry faces limitations in preserving tooth health due to the finite lifespan of restorative materials. Regenerative dentistry, utilizing stem cells and bioactive materials, offers a promising approach for regenerating dental tissues. Human dental pulp stem cells (hDPSCs) and bioactive materials like calcium phosphate (CaP) and silicate-based materials have shown potential for dental tissue regeneration. This systematic review aims to investigate the effects of CaP and silicate-based materials on hDPSCs through in vitro studies published since 2015. Following the PRISMA guidelines, a comprehensive search strategy was implemented in PubMed MedLine, Cochrane, and ScienceDirect databases. Eligibility criteria were established using the PICOS scheme. Data extraction and risk of bias (RoB) assessment were conducted, with the included studies assessed for bias using the Office of Health and Translation (OHAT) RoB tool. The research has been registered at OSF Registries. Ten in vitro studies met the eligibility criteria out of 1088 initial studies. Methodological heterogeneity and the use of self-synthesized biomaterials with limited generalizability were observed in the included study. The findings highlight the positive effect of CaP and silicate-based materials on hDPSCs viability, adhesion, migration, proliferation, and differentiation. While the overall RoB assessment indicated satisfactory credibility of the reviewed studies, the limited number of studies and methodological heterogeneity pose challenges for quantitative research. In conclusion, this systematic review provides valuable insights into the effects of CaP and silicate-based materials on hDPSCs. Further research is awaited to enhance our understanding and optimize regenerative dental treatments using bioactive materials and hDPSCs, which promise to improve patient outcomes.
    Language English
    Publishing date 2023-09-23
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2590-0064
    ISSN (online) 2590-0064
    DOI 10.1016/j.mtbio.2023.100815
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Calcium orthophosphates in dentistry.

    Dorozhkin, Sergey V

    Journal of materials science. Materials in medicine

    2013  Volume 24, Issue 6, Page(s) 1335–1363

    Abstract: ... in periodontics; however, the majority of the publications on calcium orthophosphates in dentistry are devoted ... fillers and implantable scaffolds. This review provides brief information on calcium orthophosphates and ... orthophosphates (both alone and as components of various formulations) are used in dentistry as both dental ...

    Abstract Dental caries, also known as tooth decay or a cavity, remains a major public health problem in the most communities even though the prevalence of disease has decreased since the introduction of fluorides for dental care. Therefore, biomaterials to fill dental defects appear to be necessary to fulfill customers' needs regarding the properties and the processing of the products. Bioceramics and glass-ceramics are widely used for these purposes, as dental inlays, onlays, veneers, crowns or bridges. Calcium orthophosphates belong to bioceramics but they have some specific advantages over other types of bioceramics due to a chemical similarity to the inorganic part of both human and mammalian bones and teeth. Therefore, calcium orthophosphates (both alone and as components of various formulations) are used in dentistry as both dental fillers and implantable scaffolds. This review provides brief information on calcium orthophosphates and describes in details current state-of-the-art on their applications in dentistry and dentistry-related fields. Among the recognized dental specialties, calcium orthophosphates are most frequently used in periodontics; however, the majority of the publications on calcium orthophosphates in dentistry are devoted to unspecified "dental" fields.
    MeSH term(s) Animals ; Calcium Phosphates/chemical synthesis ; Calcium Phosphates/therapeutic use ; Dental Caries/therapy ; Dental Materials/chemical synthesis ; Dental Materials/therapeutic use ; Dental Restoration, Permanent/instrumentation ; Dental Restoration, Permanent/methods ; Dental Veneers ; Humans
    Chemical Substances Calcium Phosphates ; Dental Materials
    Language English
    Publishing date 2013-03-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1031752-1
    ISSN 1573-4838 ; 0957-4530
    ISSN (online) 1573-4838
    ISSN 0957-4530
    DOI 10.1007/s10856-013-4898-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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