Article: Recognition of Double-Stranded RNA and Regulation of Interferon Pathway by Toll-Like Receptor 10.
2018 Volume 9, Page(s) 516
Abstract: Toll-like receptor (TLR)-10 remains an orphan receptor without well-characterized ligands or ... functions. Here, we reveal that TLR10 is predominantly localized to endosomes and binds dsRNA ...
| Abstract | Toll-like receptor (TLR)-10 remains an orphan receptor without well-characterized ligands or functions. Here, we reveal that TLR10 is predominantly localized to endosomes and binds dsRNA |
|---|---|
| MeSH term(s) | Endosomes/metabolism ; Humans ; Interferons/metabolism ; RNA, Double-Stranded/metabolism ; Signal Transduction ; THP-1 Cells ; Toll-Like Receptor 10/metabolism ; Toll-Like Receptor 3/metabolism |
| Chemical Substances | RNA, Double-Stranded ; TLR10 protein, human ; TLR3 protein, human ; Toll-Like Receptor 10 ; Toll-Like Receptor 3 ; Interferons (9008-11-1) |
| Language | English |
| Publishing date | 2018-03-16 |
| Publishing country | Switzerland |
| Document type | Journal Article ; Research Support, Non-U.S. Gov't |
| ZDB-ID | 2606827-8 |
| ISSN | 1664-3224 |
| ISSN | 1664-3224 |
| DOI | 10.3389/fimmu.2018.00516 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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