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Article ; Online: COVID-19 Infection: Early Lessons.

Lei, Yi / Zhang, Han-Wen / Yu, Juan / Patlas, Michael N

Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes

2020 Volume 71, Issue 3, Page(s) 251–252

MeSH term(s)	Betacoronavirus ; COVID-19 ; Coronavirus Infections/diagnostic imaging ; Humans ; Lung/diagnostic imaging ; Pandemics ; Pneumonia, Viral/diagnostic imaging ; Radiology Department, Hospital ; SARS-CoV-2 ; Tomography, X-Ray Computed/methods
Keywords	covid19
Language	English
Publishing date	2020-03-12
Publishing country	United States
Document type	Editorial
ZDB-ID	418190-6
ISSN	1488-2361 ; 0846-5371 ; 0008-2902
ISSN (online)	1488-2361
ISSN	0846-5371 ; 0008-2902
DOI	10.1177/0846537120914428
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Article: COVID-19 Infection: Early Lessons

Lei, Yi / Zhang, Han-Wen / Yu, Juan / Patlas, Michael N

Can Assoc Radiol J

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #7788
Database	COVID19

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Book ; Online ; E-Book: The Covid-19 epidemic in China

Lau, Lawrence J. / Xiong, Yanyan

2020

Abstract: ... 19 Virus -- Re-Opening -- Chapter 3 An Early Attempt at Prediction -- Introduction -- The COVID-19 ... The Lessons Learnt -- Early Action Can Make a Huge Difference -- The Importance of Extensive Testing and ... of the COVID-19 Epidemic on the Mainland -- The Beginning -- The Blockade and Lockdown -- Combatting the COVID ...

Author's details	Lawrence J. Lau, Yanyan Xiong
Abstract	Intro -- Contents -- Dedication -- Preface -- Chapter 1 Introduction -- Chapter 2 A Chronology of the COVID-19 Epidemic on the Mainland -- The Beginning -- The Blockade and Lockdown -- Combatting the COVID-19 Virus -- Re-Opening -- Chapter 3 An Early Attempt at Prediction -- Introduction -- The COVID-19 Epidemic in 2020 -- The Daily Numbers of Newly Confirmed Cases of COVID-19 -- Essential Control Measures -- Comparison with the SARS Epidemic in 2003 -- The Rise in the Daily Number of Cured Cases -- Concluding Remarks -- Chapter 4 The Big Picture -- The COVID-19 Epidemic in Mainland China -- Daily Newly Confirmed Cases and New Deaths -- Case Mortality Rates -- Per Capita Comparisons -- Population Infection Rates -- Population Mortality Rates -- The Cumulative Number of Recoveries -- Summary -- Chapter 5 Wuhan and Hubei -- Wuhan -- Hubei ex Wuhan -- Hubei -- Comparison between Wuhan and Hubei ex Wuhan -- Summary -- Chapter 6 China Outside of Hubei -- The Experience Outside of Hubei -- The Major Mainland Cities Outside of Hubei -- The Imported Cases -- Hong Kong, Macau and Taiwan -- Summary -- Chapter 7 The Costs of the COVID-19 Epidemic to China -- The Loss of GDP at the National Level -- The Loss of GDP at the Provincial Level -- The Loss of GDP in Wuhan -- The Loss of Lives -- Restoration and Normalisation -- Chapter 8 International Comparisons -- Aggregate Comparisons -- Cumulative Total Confirmed Cases -- Cumulative Total Deaths -- Case Mortality Rates -- Per Capita Comparisons -- Population Infection Rates -- Population Mortality Rates -- The Percentage Distribution of Outcomes -- Summary Comparison of Performance -- Chapter 9 The Way Forward -- The Lessons Learnt -- Early Action Can Make a Huge Difference -- The Importance of Extensive Testing and Social Distancing -- Looking to the Future -- Be Prepared for the Next Pandemic.
Keywords	Electronic books
Language	English
Size	1 Online-Ressource (ix, 214 Seiten), Diagramme
Publisher	World Scientific
Publishing place	Singapore
Publishing country	Singapore
Document type	Book ; Online ; E-Book
Note	Description based on publisher supplied metadata and other sources
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
HBZ-ID	HT020579884
ISBN	978-981-12-2251-1 ; 9789811222504 ; 981-12-2251-7 ; 9811222509
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: Application of Point-of-care Cardiac Ultrasonography in COVID-19 Infection: Lessons Learned from the Early Experience.

Xie, Mingxing / Chou, Yi-Hong / Zhang, Li / Zhang, Danqing / Tiu, Chui-Mei

Journal of medical ultrasound

2021 Volume 29, Issue 1, Page(s) 3–8

Abstract: The outbreak of the SARS-CoV-2 infection, also known as coronavirus disease 2019 (COVID-19), was ... distinguish the causes of dyspnea in febrile patients. The COVID-19 infection may play a role in unmasking or ... and Prevention to prevent transmission of infection, regardless of suspected or confirmed COVID-19. ...

Abstract	The outbreak of the SARS-CoV-2 infection, also known as coronavirus disease 2019 (COVID-19), was formally defined a pandemic by the World Health Organization (WHO) in March 2020, and is still a global health issue. Since there is a high prevalence of acute cardiac injury in patients with COVID-19 infection, point-of-care cardiac ultrasound (PoCCUS) may be used for longitudinal monitoring of patients infected with COVID-19. However, there is still limited experience on the application of PoCCUS in the COVID-19 pandemic. Within the point of care setting in our system, focused cardiac US exams were performed with specific imaging protocols on the basis of suspicion of a specific disease, such as ruling out tamponade or thrombotic complications. Our preliminary experience shows that PoCCUS helps distinguish the causes of dyspnea in febrile patients. The COVID-19 infection may play a role in unmasking or exacerbating underlying chronic cardiovascular conditions, especially in patients with inadequate past history. In hospitalized patients with COVID-19, CURB-65 score for pneumonia severity and raised D-dimer were significantly associated with deep vein thrombosis (DVT). COVID-19 patients with DVT had worse prognosis, and patients with lower leg edema deserve further evaluation by using point-of-care ultrasound for the lower legs and heart. In COVID-19 patients with arrhythmia, PoCCUS used by experienced hands may reveal abnormal right ventricle (RV) functional parameters and lead to a more comprehensive cardiac US study. When there is suspicion of cardiac disease, PoCCUS can be done first, and if information is inadequate, limited transthoracic echocardiography (TTE), and critical care echocardiography (CCE) can be followed. Ultrasound practitioners should follow the standard precautions for COVID-19 as outlined by the Centers for Disease Control and Prevention to prevent transmission of infection, regardless of suspected or confirmed COVID-19.
Language	English
Publishing date	2021-03-20
Publishing country	India
Document type	Journal Article ; Review
ISSN	0929-6441
ISSN	0929-6441
DOI	10.4103/JMU.JMU_140_20
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Article ; Online: Risk Factors and Mortality for Atypical Presentation of COVID-19 Infection in Hospitalized Patients - Lessons From the Early Pandemic.

Pop-Vicas, Aurora / Haleem, Ambar / Osman, Fauzia / Fuglestad, Ryan / Shirley, Daniel / Striker, Robert / Safdar, Nasia

WMJ : official publication of the State Medical Society of Wisconsin

2021 Volume 120, Issue 2, Page(s) 94–99

Abstract: ... as any hospitalized patient with COVID-19 infection who did not experience both fever and cough. We identified ... Objective: To assess the clinical epidemiology and outcomes of patients hospitalized with COVID-19 ... of all patients admitted during March 13, 2020 through May 13, 2020 with laboratory-confirmed COVID-19 to 3 ...

Abstract	Objective: To assess the clinical epidemiology and outcomes of patients hospitalized with COVID-19 who did not experience fever and cough during the early pandemic. Methods: Retrospective cohort of all patients admitted during March 13, 2020 through May 13, 2020 with laboratory-confirmed COVID-19 to 3 tertiary-care hospitals. Patient-level data (demographic, clinical manifestations, comorbid illnesses, inpatient treatment) were analyzed. The main outcome variable was atypical presentation, defined as any hospitalized patient with COVID-19 infection who did not experience both fever and cough. We identified risk factors for atypical presentation on univariate and multivariate analyses and assessed 30-day mortality differences via survival analysis. Results: Of 163 patients in the study, 39 (24%) were atypical. On univariate analysis, atypical cases were significantly more likely to be older, reside in a long-term-care facility (LTCF), and have underlying diabetes mellitus, stroke, or cardiac disease; present without dyspnea or myalgia, have lower C-reactive proteins (CRP) and higher beta-natriuretic peptides. They were less likely to receive intensive care unit care or specific COVID-19 treatments ( Conclusion: During the first pandemic surge, COVID-19 patients without inflammatory signs and symptoms were more likely to be LTCF residents and had higher mortality. Timely recognition of these atypical presentations may have prevented spread and improved clinical outcomes.
MeSH term(s)	Aged ; Aged, 80 and over ; COVID-19/mortality ; COVID-19/therapy ; Comorbidity ; Cough/epidemiology ; Female ; Fever/epidemiology ; Hospital Mortality ; Hospitalization ; Humans ; Long-Term Care ; Male ; Pandemics ; Pneumonia, Viral/mortality ; Pneumonia, Viral/therapy ; Retrospective Studies ; Risk Factors ; SARS-CoV-2 ; Survival Analysis ; Wisconsin/epidemiology
Language	English
Publishing date	2021-07-13
Publishing country	United States
Document type	Journal Article ; Multicenter Study
ZDB-ID	441051-8
ISSN	2379-3961 ; 0043-6542 ; 1098-1861
ISSN (online)	2379-3961
ISSN	0043-6542 ; 1098-1861
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Article: Lessons from the COVID-19 pandemic.

Lochman, I / Thon, V / Šíma, P

Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne

2024 Volume 73, Issue 1, Page(s) 51–58

Abstract: ... with the diagnosis and care of early-phase COVID-19 patients. Author's translation of the article into English is ... the disease COVID-19, which grew into a global pandemic, have remained consistently low in all countries ... available at: https://www.spadia.cz/media/2085/lessons fromthecovid-19pandemic.pdf. ...

Title translation	Poučení z pandemie covidu-19.
Abstract	The numbers of diagnosed and reported cases of infection with the SARS-CoV-2 virus causing the disease COVID-19, which grew into a global pandemic, have remained consistently low in all countries, including the Czech Republic, since May 2023, when the World Health Organization declared an end to the pandemic. However, it must be said that the measures implemented to control this infection did not meet all expectations. Although new mutations of the virus that can potentially cause disease, continue to emerge, it appears that most people have gradually learned to coexist with them. However, due to some unique properties of the SARS-CoV-2 virus and its variants, there will still be predisposed individuals who will develop illness and need hospitalization along with effective treatment to be supported and monitored by adequate laboratory tests. This article is a commentary on this issue and deals primarily with the diagnosis and care of early-phase COVID-19 patients. Author's translation of the article into English is available at: https://www.spadia.cz/media/2085/lessons fromthecovid-19pandemic.pdf.
MeSH term(s)	Humans ; COVID-19/epidemiology ; Czech Republic/epidemiology ; SARS-CoV-2 ; Pandemics
Language	English
Publishing date	2024-05-02
Publishing country	Czech Republic
Document type	Journal Article
ZDB-ID	1188216-5
ISSN	1805-451X ; 1210-7913 ; 0009-0522
ISSN (online)	1805-451X
ISSN	1210-7913 ; 0009-0522
DOI	10.61568/emi/11-6254/20240123/136242
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Article ; Online: Pediatric Plastic Surgery in the COVID-19 Era.

Levy, Lior / Villavisanis, Dillan F / Sarosi, Alex J / Taub, Peter J

Annals of plastic surgery

2024 Volume 92, Issue 3, Page(s) 335–339

Abstract: Abstract: The COVID-19 pandemic has forced the healthcare system to adopt novel strategies ... surgical care, and patient outcomes. Lessons learned help inform pediatric plastic surgeons on how ... on early triage. ...

Abstract	Abstract: The COVID-19 pandemic has forced the healthcare system to adopt novel strategies to treat patients. Pediatric plastic surgeons are uniquely exposed to high rates of infections during examinations and surgeries via aerosol-generating procedures, in part because of the predilection of viral particles for the nasal cavities and pharynx. Telemedicine has emerged as a useful virtual medium for encouraging prolonged patient follow-up while maintaining physical distance. It has proven beneficial in mitigating infection risks while decreasing the financial burden on patients, their families, and healthcare teams. New trends driven by the pandemic added multiple elements to the patient-physician relationship and have left a lasting impact on the field of pediatric plastic surgery in clinical guidelines, surgical care, and patient outcomes. Lessons learned help inform pediatric plastic surgeons on how to reduce future viral infection risk and lead a more appropriately efficient surgical team depending on early triage.
MeSH term(s)	Humans ; Child ; COVID-19/prevention & control ; Surgery, Plastic ; SARS-CoV-2 ; Pandemics/prevention & control ; Delivery of Health Care
Language	English
Publishing date	2024-02-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	423835-7
ISSN	1536-3708 ; 0148-7043
ISSN (online)	1536-3708
ISSN	0148-7043
DOI	10.1097/SAP.0000000000003810
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Article ; Online: Infection Risk Prediction in Healthcare Settings: Lessons from COVID-19 Contact Tracing.

Keskin, Salih / Emecen, Ahmet Naci / Ergör, Alp

Infectious diseases & clinical microbiology

2024 Volume 6, Issue 1, Page(s) 44–54

Abstract: Objective: Contact tracing aids epidemic control by enabling early detection and isolation ... application of contact and risk assessment-based models in predicting SARS-CoV-2 infection following exposure ... symptoms were generated using logistic regression. SARS-CoV-2 infection was defined as having a positive ...

Abstract	Objective: Contact tracing aids epidemic control by enabling early detection and isolation without overburdening healthcare systems despite potential challenges. This study aimed to evaluate the practical application of contact and risk assessment-based models in predicting SARS-CoV-2 infection following exposure among healthcare workers in a large tertiary public university hospital in Türkiye. Materials and methods: The study was designed as a retrospective cohort study, including contact tracing data from 3389 exposed healthcare workers from March 23, 2020, to October 22, 2021. Contact-based (mask use, contact duration and distance) and exposure risk-assessment-based (low, medium, high-risk) models with and without having symptoms were generated using logistic regression. SARS-CoV-2 infection was defined as having a positive SARS-CoV-2 RT-PCR test result. Adjustments were made to the models for demographic and occupational variables, previous infection, and vaccination. Model parameters were compared. Results: Of 3389 exposed healthcare workers, 2451 underwent RT-PCR testing. Among those tested, RT-PCR positivity was 5.9% (144/2451). Lack of personal protective equipment use (odds ratio [OR]=1.64, 95% confidence interval [CI]=1.03-2.66) and ≥15 minutes of contact duration (1.89, 1.21-3.09) were significantly associated with RT-PCR positivity. In the risk-assessment model, being a high-risk contact increased the odds of RT-PCR positivity (OR=2.76, 95% CI=1.61-5.03). Adding the presence of symptoms to contact-based and risk assessment models improved model parameters (Akaike information criterion [AIC]: from 1086.1 to 1083.1; Tjur's R Conclusion: The inclusion of being symptomatic improved the contact-based and risk assessment-based models. Institutions should be encouraged to incorporate symptom inquiries into risk assessment protocols in response to newly emerging respiratory virus epidemics. Institutions lacking the capacity for extensive contact tracing are recommended, at minimum, to track symptomatic exposed workers for epidemic control.
Language	English
Publishing date	2024-03-08
Publishing country	Turkey
Document type	Journal Article
ISSN	2667-646X
ISSN (online)	2667-646X
DOI	10.36519/idcm.2024.315
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Article ; Online: Lessons we learned during the past four challenging years in the COVID-19 era: pharmacotherapy, long COVID complications, and vaccine development.

Ghasemiyeh, Parisa / Mohammadi-Samani, Soliman

Virology journal

2024 Volume 21, Issue 1, Page(s) 98

Abstract: ... the effectiveness of available COVID-19 vaccines with different platforms against early SARS-CoV-2 variants and ... of COVID-19 infection, various pharmacotherapeutic agents have been examined in the management of COVID-19 ... or reduce COVID-19 infection, hospitalization, and mortality rates. In this focused review, at first ...

Abstract	About four years have passed since the detection of the first cases of COVID-19 in China. During this lethal pandemic, millions of people have lost their lives around the world. Since the first waves of COVID-19 infection, various pharmacotherapeutic agents have been examined in the management of COVID-19. Despite all these efforts in pharmacotherapy, drug repurposing, and design and development of new drugs, multiple organ involvement and various complications occurred during COVID-19. Some of these complications became chronic and long-lasting which led to the "long COVID" syndrome appearance. Therefore, the best way to eradicate this pandemic is prophylaxis through mass vaccination. In this regard, various vaccine platforms including inactivated vaccines, nucleic acid-based vaccines (mRNA and DNA vaccines), adenovirus-vectored vaccines, and protein-based subunit vaccines have been designed and developed to prevent or reduce COVID-19 infection, hospitalization, and mortality rates. In this focused review, at first, the most commonly reported clinical presentations of COVID-19 during these four years have been summarized. In addition, different therapeutic regimens and their latest status in COVID-19 management have been listed. Furthermore, the "long COVID" and related signs, symptoms, and complications have been mentioned. At the end, the effectiveness of available COVID-19 vaccines with different platforms against early SARS-CoV-2 variants and currently circulating variants of interest (VOI) and the necessity of booster vaccine shots have been summarized and discussed in more detail.
MeSH term(s)	Humans ; COVID-19/prevention & control ; COVID-19/immunology ; COVID-19 Vaccines/immunology ; COVID-19 Vaccines/adverse effects ; COVID-19 Vaccines/administration & dosage ; SARS-CoV-2/immunology ; Vaccine Development ; COVID-19 Drug Treatment ; Antiviral Agents/therapeutic use ; Post-Acute COVID-19 Syndrome ; Drug Repositioning
Chemical Substances	COVID-19 Vaccines ; Antiviral Agents
Language	English
Publishing date	2024-04-26
Publishing country	England
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2160640-7
ISSN	1743-422X ; 1743-422X
ISSN (online)	1743-422X
ISSN	1743-422X
DOI	10.1186/s12985-024-02370-6
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Article: COVID testing hesitancy among pregnant patients: Lessons learned from the COVID-19 pandemic about the unique needs and challenges of medically complex populations.

Farrell, Ruth / Dahler, Caitlin / Pope, Rachel / Divoky, Ellen / Collart, Christina

Research square

2024

Abstract: ... this study to explore pregnant patients' attitudes, access, and utilization of COVID-19 testing to support ... themes related to barriers to COVID-19 testing access and use during pregnancy, including concerns ... about test accuracy, exposure to COVID-19 in testing facilities, isolation and separation during labor and ...

Abstract	Background Pregnant patients were a significant population to consider during the pandemic, given the impact of SARS-CoV-2 infection on obstetric outcomes. While COVID testing was a central pillar of infection control, it became apparent that a subset of the population declined to test. At the same time, data emerged about pregnant persons also declining to test. Yet, it was unknown why pregnant patients declined tests and if those reasons were similar or different from those of the general population. We conducted this study to explore pregnant patients' attitudes, access, and utilization of COVID-19 testing to support healthcare for infection prevention management for this unique and medically complex population. Methods We conducted a qualitative study of patients who were currently or recently pregnant during the early stages of the pandemic and received outpatient prenatal care at one of the participating study sites. An interview guide was used to conduct in-depth telephone interviews. Coding was performed using NVivo, and analysis was conducted using Grounded Theory. Results The average age of the participants (N = 37) was 32 (SD 4.21) years. Most were < 35 years of age (57%) and self-described as White (68%). Qualitative analysis identified themes related to barriers to COVID-19 testing access and use during pregnancy, including concerns about test accuracy, exposure to COVID-19 in testing facilities, isolation and separation during labor and delivery, and diminished healthcare quality and patient experience. Conclusions The implementation of widespread and universal COVID testing policies did not address the unique needs and challenges of pregnant patients as a medically complex population. It is important to understand the reasons and implications for pregnant patients who declined COVID testing during the current pandemic to inform strategies to prevent infection spread in future public health emergencies.
Language	English
Publishing date	2024-02-01
Publishing country	United States
Document type	Preprint
DOI	10.21203/rs.3.rs-3892181/v1
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