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Article ; Online: Association of Ocular Surface Diseases With SARS-CoV-2 Infection in Six Districts of China: An Observational Cohort Study.

Li, Shengjie / Qiu, Yichao / Tang, Li / Wang, Zhujian / Cao, Wenjun / Zhou, Xingtao / Sun, Xinghuai

Frontiers in immunology

2021  Volume 12, Page(s) 695428

Abstract: ... between SARS-CoV-2 and ocular surface diseases is poorly described. Between May 2020 and March 2021 ... a total of 2, 0157 participants from six districts of China were enrolled. Serum samples were tested ... The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viruses is mainly transmitted ...

Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viruses is mainly transmitted through respiratory droplets. Notably, some coronavirus disease 2019 (COVID-19) patients have ocular manifestations, including conjunctival hyperaemia, chemosis, epiphora, and increased secretions. However, the association between SARS-CoV-2 and ocular surface diseases is poorly described. Between May 2020 and March 2021, a total of 2, 0157 participants from six districts of China were enrolled. Serum samples were tested for immunoglobulin G and M (IgG and IgM) antibodies against the SARS-CoV-2 spike protein and nucleoprotein using magnetic chemiluminescence enzyme immunoassays. Throat swabs were tested for SARS-CoV-2 RNA using RT-PCR assays in a designated virology laboratory. Fisher exact, χ
MeSH term(s) Adolescent ; Adult ; Aged ; Antibodies, Viral/blood ; Antibodies, Viral/immunology ; COVID-19/complications ; COVID-19/immunology ; Child ; Child, Preschool ; China ; Cohort Studies ; Eye Diseases/etiology ; Eye Diseases/virology ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Young Adult
Chemical Substances Antibodies, Viral
Language English
Publishing date 2021-08-06
Publishing country Switzerland
Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
ZDB-ID 2606827-8
ISSN 1664-3224 ; 1664-3224
ISSN (online) 1664-3224
ISSN 1664-3224
DOI 10.3389/fimmu.2021.695428
Database MEDical Literature Analysis and Retrieval System OnLINE

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