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  1. Article ; Online: Clinical characteristics of COVID-19 patients with complication of cardiac arrhythmia.

    Liu, Qin / Chen, Huai / Zeng, Qingsi

    The Journal of infection

    2020  Volume 81, Issue 3, Page(s) e6–e8

    MeSH term(s) Arrhythmias, Cardiac ; Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-11
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2020.07.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Clinical characteristics of COVID-19 patients with complication of cardiac arrhythmia

    Liu, Qin / Chen, Huai / Zeng, Qingsi

    Journal of Infection

    2020  Volume 81, Issue 3, Page(s) e6–e8

    Keywords Microbiology (medical) ; Infectious Diseases ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2020.07.012
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Prevalence and Clinical Implications of COVID-19 Myocarditis.

    Chimenti, Cristina / Magnocavallo, Michele / Ballatore, Federico / Bernardini, Federico / Alfarano, Maria / Della Rocca, Domenico G / Severino, Paolo / Lavalle, Carlo / Francesco, Fedele / Frustaci, Andrea

    Cardiac electrophysiology clinics

    2021  Volume 14, Issue 1, Page(s) 53–62

    Abstract: ... a comprehensive review about COVID-19-related myocarditis, including clinical characteristics, diagnostic workup ... The clinical manifestations of COVID-19 are widely variable and may involve several districts ... cardiogenic shock. In particular, myocarditis is a well-recognized severe complication of COVID-19 and is associated ...

    Abstract The clinical manifestations of COVID-19 are widely variable and may involve several districts. Although the clinical course is mostly characterized by respiratory involvement, up to 30% of hospitalized patients have evidence of myocardial injury due to acute coronary syndrome, cardiac arrhythmias, myocarditis, and cardiogenic shock. In particular, myocarditis is a well-recognized severe complication of COVID-19 and is associated with fulminant cardiogenic shock and sudden cardiac death. In this article, the authors aim to present a comprehensive review about COVID-19-related myocarditis, including clinical characteristics, diagnostic workup, and management.
    MeSH term(s) Arrhythmias, Cardiac/complications ; COVID-19/complications ; Humans ; Myocarditis/complications ; Myocarditis/diagnosis ; Myocarditis/epidemiology ; Prevalence ; SARS-CoV-2
    Language English
    Publishing date 2021-11-09
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1877-9190
    ISSN (online) 1877-9190
    DOI 10.1016/j.ccep.2021.11.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Clinical characteristics of COVID-19 with cardiac injury: a systematic review and meta-analysis.

    Zeng, Linwen / Wang, Shihui / Cai, Jianing / Sun, Shaoqing / Wang, Suhuai / Li, Jingjie / Sun, Lin

    Epidemiology and infection

    2020  Volume 148, Page(s) e266

    Abstract: ... we carried out a systematic analysis of clinical characteristics in COVID-19 patients to determine potential ... that early prevention should be applied to COVID-19 patients with cardiac injury to reduce adverse outcomes. ... found that patients with cardiac injury did not present higher clinical specificity for chest distress ...

    Abstract Objectives: Cardiac injury is associated with poor prognosis of 2019 novel coronavirus disease 2019 (COVID-19), but the risk factors for cardiac injury have not been fully studied. In this study, we carried out a systematic analysis of clinical characteristics in COVID-19 patients to determine potential risk factors for cardiac injury complicated COVID-19 virus infection.
    Methods: We systematically searched relevant literature published in Pubmed, Embase, Europe PMC, CNKI and other databases. All statistical analyses were performed using STATA 16.0.
    Results: We analysed 5726 confirmed cases from 17 studies. The results indicated that compared with non-cardiac-injured patients, patients with cardiac injury are older, with a greater proportion of male patients, with higher possibilities of existing comorbidities, with higher risks of clinical complications, need for mechanical ventilation, ICU transfer and mortality. Moreover, C-reactive protein, procalcitonin, D-dimer, NT-proBNP and blood creatinine in patients with cardiac injury are also higher while lymphocyte counts and platelet counts decreased. However, we fortuitously found that patients with cardiac injury did not present higher clinical specificity for chest distress (P = 0.304), chest pain (P = 0.334), palpitations (P = 0.793) and smoking (P = 0.234). Similarly, the risk of concomitant arrhythmia (P = 0.103) did not increase observably either.
    Conclusion: Age, male gender and comorbidities are risk factors for cardiac injury complicated COVID-19 infection. Such patients are susceptible to complications and usually have abnormal results of laboratory tests, leading to poor outcomes. Contrary to common cardiac diseases, cardiac injury complicated COVID-19 infection did not significantly induce chest distress, chest pain, palpitations or arrhythmias. Our study indicates that early prevention should be applied to COVID-19 patients with cardiac injury to reduce adverse outcomes.
    MeSH term(s) Age Factors ; Betacoronavirus ; COVID-19 ; Comorbidity ; Coronavirus Infections/complications ; Coronavirus Infections/pathology ; Heart Diseases/complications ; Heart Diseases/pathology ; Humans ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/pathology ; Risk Factors ; SARS-CoV-2 ; Sex Factors
    Keywords covid19
    Language English
    Publishing date 2020-10-23
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Systematic Review
    ZDB-ID 632982-2
    ISSN 1469-4409 ; 0950-2688
    ISSN (online) 1469-4409
    ISSN 0950-2688
    DOI 10.1017/S0950268820002587
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Patient characteristics, clinical course and factors associated to ICU mortality in critically ill patients infected with SARS-CoV-2 in Spain: A prospective, cohort, multicentre study.

    Ferrando, C / Mellado-Artigas, R / Gea, A / Arruti, E / Aldecoa, C / Bordell, A / Adalia, R / Zattera, L / Ramasco, F / Monedero, P / Maseda, E / Martínez, A / Tamayo, G / Mercadal, J / Muñoz, G / Jacas, A / Ángeles, G / Castro, P / Hernández-Tejero, M /
    Fernandez, J / Gómez-Rojo, M / Candela, Á / Ripollés, J / Nieto, A / Bassas, E / Deiros, C / Margarit, A / Redondo, F J / Martín, A / García, N / Casas, P / Morcillo, C / Hernández-Sanz, M L

    Revista espanola de anestesiologia y reanimacion

    2020  Volume 67, Issue 8, Page(s) 425–437

    Abstract: ... clinical characteristics and clinical course of ICU COVID-19 patients, and to determine risk factors ... Background: The clinical course of COVID-19 critically ill patients, during their admission ... for ICU mortality of COVID-19 patients.: Methods: Prospective, multicentre, cohort study that enrolled ...

    Title translation Características, evolución clínica y factores asociados a la mortalidad en UCI de los pacientes críticos infectados por SARS-CoV-2 en España: estudio prospectivo, de cohorte y multicéntrico.
    Abstract Background: The clinical course of COVID-19 critically ill patients, during their admission in the intensive care unit (UCI), including medical and infectious complications and support therapies, as well as their association with in-ICU mortality has not been fully reported.
    Objective: This study aimed to describe clinical characteristics and clinical course of ICU COVID-19 patients, and to determine risk factors for ICU mortality of COVID-19 patients.
    Methods: Prospective, multicentre, cohort study that enrolled critically ill COVID-19 patients admitted into 30 ICUs from Spain and Andorra. Consecutive patients from March 12
    Results: A total of 663 patients were included. Overall ICU mortality was 31% (203 patients). At ICU admission non-survivors were more hypoxemic [SpO
    Conclusions: Older COVID-19 patients with higher APACHE II scores on admission, those who developed AKI grades ii or iii and/or septic shock during ICU stay had an increased risk-of-death. ICU mortality was 31%.
    MeSH term(s) APACHE ; Acute Kidney Injury/epidemiology ; Age Factors ; Aged ; Andorra/epidemiology ; Antiviral Agents/therapeutic use ; Arrhythmias, Cardiac/epidemiology ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/blood ; Coronavirus Infections/complications ; Coronavirus Infections/mortality ; Coronavirus Infections/therapy ; Critical Illness ; Female ; Hospital Mortality ; Humans ; Hypoxia/epidemiology ; Intensive Care Units/statistics & numerical data ; Length of Stay ; Male ; Middle Aged ; Odds Ratio ; Oxygen/administration & dosage ; Pandemics ; Pneumonia, Viral/blood ; Pneumonia, Viral/complications ; Pneumonia, Viral/mortality ; Pneumonia, Viral/therapy ; Prospective Studies ; Regression Analysis ; Respiratory Therapy/methods ; Risk Factors ; SARS-CoV-2 ; Severe Acute Respiratory Syndrome/epidemiology ; Shock/epidemiology ; Spain/epidemiology
    Chemical Substances Antiviral Agents ; Oxygen (S88TT14065)
    Keywords covid19
    Language Spanish
    Publishing date 2020-07-13
    Document type Journal Article ; Multicenter Study ; Observational Study
    ISSN 2341-1929
    ISSN (online) 2341-1929
    DOI 10.1016/j.redar.2020.07.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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