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Article ; Online: COVID-19 and Pregnancy: A Case Study.

Long, Rui / Wu, Di / Lin, Xingguang / Lv, Dan / Wang, Renjie / Jin, Lei / Liao, Shujie / Liu, Weiliang / Deng, Dongrui

Global challenges (Hoboken, NJ)

2021 Volume 5, Issue 8, Page(s) 2000074

Abstract: ... exposed to SARS-CoV-2 at 34+1 weeks gestation and chose to continue pregnancy is reported. Without obvious ... The 2019 novel coronavirus disease is spreading all over the world. Pregnant women and infants ... require particular concern, owing to the special immune conditions. A case of a pregnant woman who was ...

Abstract	The 2019 novel coronavirus disease is spreading all over the world. Pregnant women and infants require particular concern, owing to the special immune conditions. A case of a pregnant woman who was exposed to SARS-CoV-2 at 34+1 weeks gestation and chose to continue pregnancy is reported. Without obvious symptoms or signs, the woman did not receive any treatment before delivery, and gave birth at 37+5 weeks to a neonate with positive immunoglobulin G for SARS-CoV-2 and negative nucleic acid tests. The mother was given anti-infection, oxytocin, and fluid rehydration treatment after delivery. Both mother and infant recovered well after a three-month follow-up. Continued expectation to deliver at term instead of preterm can decrease the potential risk of severe perinatal and infant complications and is beneficial to the development of the neonate. More studies are required to confirm the presence of vertical transmission.
Language	English
Publishing date	2021-05-13
Publishing country	Germany
Document type	Journal Article
ISSN	2056-6646
ISSN (online)	2056-6646
DOI	10.1002/gch2.202000074
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Article ; Online: Impact of COVID-19 infection in pregnancy and neonates: A case control study.

Daclin, Camille / Carbonnel, Marie / Rossignol, Manon / Abbou, Hind / Trabelsi, Hela / Cimmino, Aminata / Delmas, Justine / Rifai, Anne-Sophie / Coiquaud, Lou-Andréa / Tiberon, Audrey / Guen, Morgan Le / Ayoubi, Jean-Marc

Journal of gynecology obstetrics and human reproduction

2022 Volume 51, Issue 5, Page(s) 102366

Abstract: ... 19 during pregnancy.: Study design: A Case control retrospective study was conducted ... were few complications associated with COVID-19 infection among pregnant patients and their neonates ... in an Obstetrical Department of a west Parisian area during the first year of COVID-19 pandemic. Maternal and ...

Abstract	Objective: To evaluate maternal and neonatal outcomes of pregnant women who were infected by COVID-19 during pregnancy. Study design: A Case control retrospective study was conducted in an Obstetrical Department of a west Parisian area during the first year of COVID-19 pandemic. Maternal and neonatal outcomes were compared between a group of women infected by the SARS-CoV-2 virus during pregnancy (March 2020- February 2021) and a control group of women delivering before pandemic. They were matched according to age and parity. Subgroups of SARS-CoV-2 infection occurring before vs after 37 weeks of gestations and symptomatic vs asymptomatic patients were analyzed. The rate of preterm birth, preeclampsia, placental abruption and stillbirth were compared between the year of pandemic and the year before for all deliveries. Results: Maternal and neonatal outcomes were similar. Among the 86 pregnant women with SARS-CoV-2 infection, five were admitted to Hospital (5.8%). One was transferred in intensive care unit for respiratory distress (1.2%). All patients had favorable outcomes. Patients with symptoms had more associated comorbidities (34.5%, n = 20/58, with symptoms, vs 9,1%, n = 2/22, without symptoms, p = 0.023). No differences in preeclampsia, placenta abruption and stillbirth, but less preterm births (4.9%, n = 160/3383 vs 6.2%, n = 209/3235, p = 0.04) were observed between the year of pandemic and the year before. Conclusion: There were few complications associated with COVID-19 infection among pregnant patients and their neonates. A low rate of associated comorbidities, a good access to healthcare services in this area and the small sample size of patients could explain these results.
MeSH term(s)	COVID-19/epidemiology ; Case-Control Studies ; Female ; Humans ; Infant, Newborn ; Pandemics ; Placenta ; Pre-Eclampsia/epidemiology ; Pregnancy ; Pregnancy Complications, Infectious/diagnosis ; Pregnancy Complications, Infectious/epidemiology ; Premature Birth/epidemiology ; Retrospective Studies ; SARS-CoV-2 ; Stillbirth/epidemiology
Language	English
Publishing date	2022-03-25
Publishing country	France
Document type	Journal Article
ISSN	2468-7847
ISSN (online)	2468-7847
DOI	10.1016/j.jogoh.2022.102366
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Article ; Online: Social and cognitive vulnerability to COVID-19-related stress in pregnancy: A case-matched-control study of antenatal mental health.

Songco, Annabel / Minihan, Savannah / Fox, Elaine / Ladouceur, Cecile / Mewton, Louise / Moulds, Michelle / Pfeifer, Jennifer / Van Harmelen, Anne-Laura / Schweizer, Susanne

Journal of affective disorders

2023 Volume 325, Page(s) 739–746

Abstract: ... increases in clinical levels of depressive and anxiety symptoms during COVID-19. This pre-registered study ... examined cognitive and social vulnerability factors for poor mental health in pregnancy during COVID-19 ... that COVID-19-related stress was associated with heightened levels of depression and anxiety during pregnancy ...

Abstract	Emerging evidence shows that compared to pre-pandemic norms pregnant women report significant increases in clinical levels of depressive and anxiety symptoms during COVID-19. This pre-registered study examined cognitive and social vulnerability factors for poor mental health in pregnancy during COVID-19. Understanding vulnerability profiles is key to identifying women at risk for deteriorating peripartum mental health. N = 742 pregnant women and N = 742 age and country-matched controls from the COVID-19 Risks Across the Lifespan Study were included. Using a case-match control design allowed us to explore whether the cognitive vulnerability profiles would differ between pregnant and non-pregnant women. The findings showed that COVID-19-related stress was associated with heightened levels of depression and anxiety during pregnancy. Its impact was greatest in women with cognitive (i.e., higher intolerance of uncertainty and tendency to worry) and social (i.e., higher level of self-reported loneliness) vulnerabilities. Importantly, our data show that the mental health impacts of the pandemic were greater in pregnant women compared to women who were not pregnant, especially those with cognitive and social vulnerabilities. The results highlight the urgent need to prioritize mental health care for pregnant women to mitigate the impact of COVID-19-related stress on women's postpartum mental health and their infants' well-being.
MeSH term(s)	Infant ; Female ; Humans ; Pregnancy ; Mental Health ; COVID-19/epidemiology ; Anxiety/epidemiology ; Anxiety Disorders ; Cognition ; Depression/epidemiology
Language	English
Publishing date	2023-01-20
Publishing country	Netherlands
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	135449-8
ISSN	1573-2517 ; 0165-0327
ISSN (online)	1573-2517
ISSN	0165-0327
DOI	10.1016/j.jad.2023.01.053
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Article ; Online: The role of eosinophil as a diagnostic, differential, and prognostic marker for Covid-19 during pregnancy: Case-control study from tertiary center.

Atalay, Aysegul / Sinaci, Selcan / Besimoglu, Berhan / Ozkavak, Onur / Kaya, Ecem / Kara, Ozgur / Sahin, Dilek

The journal of obstetrics and gynaecology research

2023 Volume 49, Issue 8, Page(s) 2063–2072

Abstract: ... case-control study was conducted including pregnant women tested simultaneously for SARS-CoV-2 by RT-PCR and ... whether eosinopenia could be similar or superior to lymphopenia in pregnancy with Covid-19.: Methods: Retrospective ... Covid-19 patient group and (n = 1889) as Covid-19 group. Covid-19 group was divided into three subgroups ...

Abstract	Purpose: To evaluate the level of eosinophil count in Covid-19 pregnant patients as a cost-effective tool for aiding in diagnosis, differential diagnosis, and prognosis and, to assess whether eosinopenia could be similar or superior to lymphopenia in pregnancy with Covid-19. Methods: Retrospective case-control study was conducted including pregnant women tested simultaneously for SARS-CoV-2 by RT-PCR and complete blood count (CBC). Eosinophil counts (EOS), lymphocytes (LYM), neutrophils (NEU) with calculation of EOS/LYM ratio, EOS/NEU ratio, NEU/LYM ratio, LYM/NEU ratio (LNR), eosinopenia, and lymphopenia were compared between the groups. ROC analysis was performed for determination of optimal cut-off values and comparative analysis between AUC were performed using the paired sample design. Logistic regression was used to determine the factors affecting the categorical variables. Results: Four thousand two hundred sixteen pregnant women were included in the final analysis of which (n = 845) as healthy control group, (n = 1482) as non Covid-19 patient group and (n = 1889) as Covid-19 group. Covid-19 group was divided into three subgroups based on severity. To diagnose and distinguish Covid-19 from other infectious conditions, EOS had better performance with higher area under curve (AUC) (0.769 and 0.757 AUC, respectively, p < 0.001). Categorically, eosinopenia had better diagnostic (Covid-19 vs. healthy), prognostic (severe-critical vs. mild-moderate), and differential diagnostic (Covid-19 vs. non Covid-19) performance than lymphopenia (OR = 5.5 vs. 3.4, OR = 3.4 vs. 1.8, OR = 5.4 vs. 2.7 p = 0.000). Conclusion: Eosinopenia is a low-cost, reliable, and convenient marker for Covid-19 not only in diagnosis, but also in prognosis by acting as an early marker for predicting severe-critical cases.
MeSH term(s)	Pregnancy ; Humans ; Female ; COVID-19/diagnosis ; Case-Control Studies ; Eosinophils ; SARS-CoV-2 ; Retrospective Studies ; Prognosis ; ROC Curve ; Lymphopenia ; Thrombocytopenia ; COVID-19 Testing
Language	English
Publishing date	2023-06-12
Publishing country	Australia
Document type	Journal Article
ZDB-ID	1327307-3
ISSN	1447-0756 ; 1341-8076
ISSN (online)	1447-0756
ISSN	1341-8076
DOI	10.1111/jog.15713
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Article: Virological and clinical features of acute respiratory failure associated with COVID-19 in pregnancy: a case-control study.

Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

2023 Volume 24, Issue 3, Page(s) 242–250

Abstract: Objective: ...

Abstract	Objective:
Language	English
Publishing date	2023-10-18
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2401976-8
ISSN	1441-2772
ISSN	1441-2772
DOI	10.51893/2022.3.OA3
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Article ; Online: Description of maternal and neonatal adverse events in pregnant people immunised with COVID-19 vaccines during pregnancy in the CLAP NETWORK of sentinel sites. Nested case-control analysis of the immunization-associated risk: A study protocol.

Macías Saint-Gerons, Diego / Castro, José Luis / Colomar, Mercedes / Rojas, Edgard / Sosa, Claudio / Ropero, Alba Maria / Serruya, Suzanne Jacob / Pastor, Desiré / Chiu, Monica / Velandia-Gonzalez, Martha / Abalos, Edgardo / Durán, Pablo / Gomez Ponce de León, Rodolfo / Tomasso, Giselle / Mainero, Luis / Rubino, Marcelo / De Mucio, Bremen

BMJ open

2024 Volume 14, Issue 1, Page(s) e073095

Abstract: ... cohort nested case-control study in pregnant people who attended maternity hospitals from eight ... to COVID-19 vaccines will be estimated. Each case will be matched with two groups of three randomly ... the risks, and therefore, vaccination is recommended during pregnancy. However, additional information is ...

Abstract	Introduction: COVID-19 is associated with higher morbimortality in pregnant people compared with non-pregnant people. At present, the benefits of maternal immunisation are considered to outweigh the risks, and therefore, vaccination is recommended during pregnancy. However, additional information is needed on the safety of the vaccines in this population. Methods and analysis: This a retrospective cohort nested case-control study in pregnant people who attended maternity hospitals from eight Latin American and Caribbean countries. A perinatal electronic clinical history database with neonatal and obstetric information will be used. The proportion of pregnant people immunised with COVID-19 vaccines of the following maternal and neonatal events will be described: preterm infant, small for gestational age, low birth weight, stillbirth, neonatal death, congenital malformations, maternal near miss and maternal death. Moreover, the risk of prematurity, small for gestational age and low birth weight associated with exposure to COVID-19 vaccines will be estimated. Each case will be matched with two groups of three randomly selected controls. Controls will be matched by hospital and mother's age (±3 years) with an additional matching by delivery date and conception time in the first and second control groups, respectively. The estimated required sample size for the main analysis (exposure to any vaccine) concerning 'non-use' is at least 1009 cases (3027 controls) to detect an increased probability of vaccine-associated event risk of 30% and at least 650 cases (1950 controls) to detect 30% protection. Sensitivity and secondary analyses considering country, type of vaccine, exposure windows and completeness of immunisation will be reported. Ethics: The study protocol was reviewed by the Ethical Review Committee on Research of the Pan American Health Organization. Patient informed consent was waived due to the retrospective design and the utilisation of anonymised data (Ref. No: PAHOERC.0546.01). Results will be disseminated in open access journals.
MeSH term(s)	Female ; Humans ; Infant, Newborn ; Pregnancy ; Case-Control Studies ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Fetal Growth Retardation ; Immunization ; Infant, Premature ; Retrospective Studies ; Stillbirth/epidemiology ; Vaccination/methods ; Vaccines ; Clinical Trials as Topic
Chemical Substances	COVID-19 Vaccines ; Vaccines
Language	English
Publishing date	2024-01-29
Publishing country	England
Document type	Clinical Trial Protocol ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2023-073095
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Article: Obesity during Pregnancy and SARS-CoV-2/COVID-19-Case Series of the Registry Study "COVID-19 Related Obstetric and Neonatal Outcome Study" (CRONOS-Network).

Weschenfelder, Friederike / Zöllkau, Janine / Schohe, Anna / Pecks, Ulrich / Groten, Tanja / Schaefer-Graf, Ute / On Behalf Of Cronos-Network

Journal of clinical medicine

2023 Volume 12, Issue 6

Abstract: ... outcomes in pregnant women with COVID-19. (2) Methods: Data from the COVID-19 Related Obstetric and Neonatal ... of our study was to investigate whether obesity is an independent risk factor for severe maternal and neonatal ... Outcome Study (CRONOS), a prospective multicenter registry for SARS-CoV-2 positive pregnant women, was used ...

Abstract	(1) Background: Obesity is an increasing challenge in the care of pregnant women. The aim of our study was to investigate whether obesity is an independent risk factor for severe maternal and neonatal outcomes in pregnant women with COVID-19. (2) Methods: Data from the COVID-19 Related Obstetric and Neonatal Outcome Study (CRONOS), a prospective multicenter registry for SARS-CoV-2 positive pregnant women, was used to analyze the effect of obesity on selected individual and combined outcome parameters (3) Results: With 20.1%, the prevalence of obesity in the CRONOS registry exceeds the German background rate of 17.5%. Obese women showed significantly higher rates of GDM (20.4% vs. 7.6%;
Language	English
Publishing date	2023-03-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12062089
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Article: Investigating vertical transmission and maternofoetal outcomes in pregnant women with COVID-19: a case-control study from Pakistan.

Khan, Samra / Fayyaz, Sharmeen / Irfan, Muhammad / Shakeel, Muhammad / Talbani, Zaib-Un-Nisa / Imran, Sajida / Shafi, Muhammad Khalid / Bashir, Imtiaz / Khan, Ishtiaq Ahmed

JPMA. The Journal of the Pakistan Medical Association

2024 Volume 74, Issue 1 (Supple-2), Page(s) S33–S38

Abstract: ... 2019 infection in pregnancy and its obstetrical and neonatal outcomes was assessed. Products ... to the neonates.: Methods: The prospective, case-control study was conducted at Zainab Panjwani Memorial ... B1, and those who tested positive for polymerase chain reaction were called the positive case group ...

Abstract	Objectives: To estimate the frequency of severe acute respiratory syndrome coronavirus-2 among pregnant women, the impact in terms of obstetrical and clinical outcomes and vertical transmission to the neonates. Methods: The prospective, case-control study was conducted at Zainab Panjwani Memorial Hospital, Karachi, from March to December 2021, and comprised pregnant women regardless of gestational age who exhibited symptoms or had a suspicion of exposure to any confirmed coronavirus disease-2019 individual. They were screened for severe acute respiratory syndrome coronavirus-2 infection using polymerase chain reaction or serology. Those who tested negative were designated as control group A, while who had a positive serology result along with a negative polymerase chain reaction were taken as recovered case group B1, and those who tested positive for polymerase chain reaction were called the positive case group B2. Groups B1 and B2 were followed up till delivery. The clinical presentation of coronavirus disease-2019 infection in pregnancy and its obstetrical and neonatal outcomes was assessed. Products of conception were tested for the detection of the severe acute respiratory syndrome coronavirus-2 genome. The viral genome from group B2 cases was sequenced to confirm vertical transmission. Data was analysed using GraphPad Prism V8. Results: Of the 139 pregnant women, 74(53.2%) were in group A with mean age 25.87±6.90 years, 49(35.3%) were in group B1 with mean age 25.53±7.02 years, and 16(11.5%) were in group B2 with mean age 27.12±5.03 years. The gestational age at which termination of pregnancy occurred was 38.3±1.26 weeks in group B1 and 38.3±1.85 weeks for group B2. There were 96 neonates across the 3 groups. Of the 11(11.45%) neonates in group B2, 1(9.09%) had postnatal transmission of severe acute respiratory syndrome coronavirus-2 and this mother-neonate case was taken as the Indexed case. The severe acute respiratory syndrome coronavirus-2 genome isolated from the neonate showed similar mutations as the viral strain infecting the mother. Conclusion: The risk of vertical transmission was found to be low. The severe acute respiratory syndrome coronavirus-2 genome was the same for both the mother and the neonate.
MeSH term(s)	Infant, Newborn ; Pregnancy ; Female ; Humans ; Adolescent ; Young Adult ; Adult ; COVID-19/epidemiology ; Pregnant Women ; Case-Control Studies ; Pregnancy Complications, Infectious/epidemiology ; Pregnancy Complications, Infectious/diagnosis ; Pakistan/epidemiology ; Prospective Studies ; SARS-CoV-2 ; Infectious Disease Transmission, Vertical ; Pregnancy Outcome/epidemiology
Language	English
Publishing date	2024-02-20
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	603873-6
ISSN	0030-9982
ISSN	0030-9982
DOI	10.47391/JPMA-DUHS-S08
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Article ; Online: Use of Extracorporeal Membrane Oxygenation Therapy During Pregnancy and COVID-19: A Case Study.

Kaplow, Roberta / Miller, Casey

AACN advanced critical care

2022 Volume 33, Issue 3, Page(s) 247–252

Abstract: ... on its use in pregnancy. This case study describes the use of venovenous extracorporeal membrane oxygenation ... in a young pregnant woman with acute respiratory distress syndrome due to COVID-19. It illustrates ... with acute respiratory distress syndrome related to COVID-19. Although recent research provides much insight ...

Abstract	Extracorporeal membrane oxygenation is emerging as a vital resource for survival of patients with acute respiratory distress syndrome related to COVID-19. Although recent research provides much insight into the advantages of extracorporeal membrane oxygenation in this patient population, little has been published on its use in pregnancy. This case study describes the use of venovenous extracorporeal membrane oxygenation in a young pregnant woman with acute respiratory distress syndrome due to COVID-19. It illustrates the benefits of a multidisciplinary approach to this treatment modality, allowing time for a fetus to become viable while preserving the life of the mother. In this case, the mother was able to return home after receiving this therapy and resume normal activities of daily living independently.
MeSH term(s)	Activities of Daily Living ; COVID-19/therapy ; Extracorporeal Membrane Oxygenation ; Female ; Humans ; Pregnancy ; Respiratory Distress Syndrome/therapy
Language	English
Publishing date	2022-08-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	2239949-5
ISSN	1559-7776 ; 1559-7768
ISSN (online)	1559-7776
ISSN	1559-7768
DOI	10.4037/aacnacc2022111
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Book ; Online: COVID-19 : Impact on Public Health and Healthcare

Batra, Kavita / Sharma, Manoj

2022

Keywords	Humanities ; Social interaction ; COVID-19 ; novel coronavirus ; social lockdown ; protection motivation theory ; health behavior ; health communication ; pregnant woman ; coronavirus ; infectious disease transmission ; vertical transmission ; obstetric management ; SARS-CoV-2 ; systematic review ; computerized tomography ; pneumonia ; risk factors ; echocardiography ; healthcare ; mental health ; Impact of event scale ; negative attitude ; Saudi Arabian females ; health services ; cost ; manual therapy ; chiropractic ; osteopathy ; physiotherapy ; direct RT-PCR ; molecular detection ; dental care ; dental health services ; dental visits ; dental service use ; postponed dental visits ; check-up ; dental examination ; pain ; dental complaints ; oral health ; Saudi Arabia ; blood donors ; seroprevalence ; ELISA ; antibodies ; lockdown ; multi-theory model ; behavior change ; pandemic ; handwashing ; young adults ; college students ; protective behavior changes ; individual ; family ; environmental factor ; COVID-19 spreading ; online survey ; awareness and knowledge ; ships ; seafarers ; SARS-COV-2 ; anxiety ; depression ; stress ; suicidal ideation ; students ; time-series ; ARIMA ; forecasting ; confirmed cases ; infectious disease ; international cruises ; health policy and regulation ; control strategies ; international cooperation ; global health governance ; ICF ; healthcare services ; interprofessional education ; medical students ; pharmacy students ; telehealth ; older adults ; artificial intelligence ; machine learning ; bibliometric analysis ; health ; novel design ; fabrication ; automated dispenser ; LDR based controller ; reduction of COVID-19 spread ; psychological symptom ; college student ; avoidance of infection ; social distancing ; free tickets for the aged ; subway use demand ; e-learning ; youth and children health ; visual health ; myopia ; routine care ; global pandemic ; role conflict ; role ambiguity ; social support ; dental precautions ; dental students ; India ; infection control ; knowledge ; perception ; survey ; face masks ; young people ; behaviors ; dentist ; infection control practices ; concerns ; dental practice ; social isolation ; social connectedness ; loneliness ; technology ; internet ; smartphones ; m-health ; severe acute respiratory syndrome ; post-graduate year training ; self-efficacy ; emotional traits ; Coronavirus ; prevention ; community ; public health nurse ; telephone consultation ; vaccine literacy ; Japan ; family carers for older adults ; sustainable ageing society ; health communications ; mass media ; HCWs ; personality traits ; intolerance of uncertainty ; coping strategies ; perceived stress ; resilience ; migration ; refugees ; fear ; modeling ; data analysis ; assessment ; effectiveness ; incidence rate ; restriction ; epidemic pattern ; exponential growth ; basic reproduction number (R0) ; spatio-temporal analysis ; demographic risk factor ; observational study ; public health ; Southeast Asia (SEA) ; vaccination rate ; basic reproduction number ; SARS-CoV ; African American ; COVID-19 vaccine ; vaccine hesitancy ; vaccine hesitant ; text classification ; SARS-CoV-2 infection ; survival rate ; hospitalized patients ; Hidalgo Mexico ; multimorbidity ; vaccination ; level 1 trauma ; health care workers ; information source trust ; COVID-19 stressor ; global south
Size	1 electronic resource (133 pages)
Publisher	MDPI - Multidisciplinary Digital Publishing Institute
Publishing place	Basel
Document type	Book ; Online
Note	English ; Open Access
HBZ-ID	HT021291262
ISBN	9783036528441 ; 303652844X
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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