Article: Effect of liver injury on prognosis and treatment of hospitalized patients with COVID-19 pneumonia.
Annals of translational medicine
2021 Volume 9, Issue 1, Page(s) 10
Abstract: ... injury on the prognosis and treatment of patients with COVID-19 pneumonia.: Methods ... However, liver injury had no negative effect on the prognosis and treatment of COVID-19 pneumonia. ... In this retrospective, single-center study, data on 109 hospitalized patients with COVID-19 pneumonia were extracted and ...
| Abstract | Background: Liver injury is common in patients with coronavirus disease 2019 (COVID-19), although its effect on patient outcomes has not been well studied. This study aimed to evaluate the effect of liver injury on the prognosis and treatment of patients with COVID-19 pneumonia. Methods: In this retrospective, single-center study, data on 109 hospitalized patients with COVID-19 pneumonia were extracted and analyzed. The primary composite end-point event was the use of mechanical ventilation or death. Results: At admission, of the 109 patients enrolled, 56 patients (51.4%) were diagnosed with severe disease, and 39 (35.8%) presented with liver injury, which mainly manifested as elevated levels of alanine aminotransferase (ALT) or aspartate aminotransferase (AST) accompanied simultaneously by an increase in the level of γ-glutamyl transferase. A primary composite end-point event occurred in 21 patients (19.3%). Liver injury was more prevalent in patients with severe disease than in those with non-severe disease (46.4% Conclusions: Liver injury was more common in severe cases of COVID-19 pneumonia than in non-severe cases. However, liver injury had no negative effect on the prognosis and treatment of COVID-19 pneumonia. |
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| Language | English |
| Publishing date | 2021-01-21 |
| Publishing country | China |
| Document type | Journal Article |
| ZDB-ID | 2893931-1 |
| ISSN | 2305-5847 ; 2305-5839 |
| ISSN (online) | 2305-5847 |
| ISSN | 2305-5839 |
| DOI | 10.21037/atm-20-4850 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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