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  1. Article: Long-Term Outcomes of Patients with Coronavirus Disease 2019 at One Year after Hospital Discharge.

    Maestre-Muñiz, Modesto M / Arias, Ángel / Mata-Vázquez, Emilia / Martín-Toledano, María / López-Larramona, Germán / Ruiz-Chicote, Ana María / Nieto-Sandoval, Bárbara / Lucendo, Alfredo J

    Journal of clinical medicine

    2021  Volume 10, Issue 13

    Abstract: ... to investigate post-acute health consequences and mortality one year after hospital discharge.: Methods ... 5% and 25% of patients. Post-COVID-19 syndrome was assessed in 543 patients at one year ... All surviving adult patients who were discharged after hospital admission due to acute COVID-19 in the first ...

    Abstract Background: The long-term effects of COVID-19 remain largely unclear. This study aims to investigate post-acute health consequences and mortality one year after hospital discharge.
    Methods: All surviving adult patients who were discharged after hospital admission due to acute COVID-19 in the first wave of the pandemic underwent a comprehensive interview. Functional assessment was performed in patients aged over 65. Clinical and hospital records were reviewed and mortality causes assessed.
    Results: A total of 587 patients with COVID-19 were discharged from hospital, including 266 after hospital admission and 321 from the emergency room. Mortality within the following year occurred in 34/266 (12.8%) and 10/321 (3.1%), respectively, due to causes directly or possibly related to COVID-19 in 20.5% and 25% of patients. Post-COVID-19 syndrome was assessed in 543 patients at one year from discharge. Any clinical complaint was reported by 90.1% of patients who needed hospitalization and 80.4% of those discharged from the emergency room (
    Conclusions: One-year mortality among survivors of acute COVID-19 was 7.5%. A significant proportion of COVID-19 patients experienced ongoing symptoms at 1 year from onset of the disease.
    Language English
    Publishing date 2021-06-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm10132945
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Long-Term Outcomes of Patients with Coronavirus Disease 2019 at One Year after Hospital Discharge

    Modesto M. Maestre-Muñiz / Ángel Arias / Emilia Mata-Vázquez / María Martín-Toledano / Germán López-Larramona / Ana María Ruiz-Chicote / Bárbara Nieto-Sandoval / Alfredo J. Lucendo

    Journal of Clinical Medicine, Vol 10, Iss 2945, p

    2021  Volume 2945

    Abstract: ... 25% of patients. Post-COVID-19 syndrome was assessed in 543 patients at one year from discharge ... to investigate post-acute health consequences and mortality one year after hospital discharge. Methods ... 19 patients experienced ongoing symptoms at 1 year from onset of the disease. ...

    Abstract Background: The long-term effects of COVID-19 remain largely unclear. This study aims to investigate post-acute health consequences and mortality one year after hospital discharge. Methods: All surviving adult patients who were discharged after hospital admission due to acute COVID-19 in the first wave of the pandemic underwent a comprehensive interview. Functional assessment was performed in patients aged over 65. Clinical and hospital records were reviewed and mortality causes assessed. Results: A total of 587 patients with COVID-19 were discharged from hospital, including 266 after hospital admission and 321 from the emergency room. Mortality within the following year occurred in 34/266 (12.8%) and 10/321 (3.1%), respectively, due to causes directly or possibly related to COVID-19 in 20.5% and 25% of patients. Post-COVID-19 syndrome was assessed in 543 patients at one year from discharge. Any clinical complaint was reported by 90.1% of patients who needed hospitalization and 80.4% of those discharged from the emergency room ( p = 0.002), with breathlessness (41.6%), tiredness (35.4%), ageusia (30.2%), and anosmia (26.3%) being the most common complaints. Ongoing symptoms attributed to COVID-19 were reported by 66.8% and 49.5% of patients, respectively ( p < 0.001). Newly developed COPD, asthma, diabetes, heart failure, and arthritis—as well as worsening of preexisting comorbidities—were found. Conclusions: One-year mortality among survivors of acute COVID-19 was 7.5%. A significant proportion of COVID-19 patients experienced ongoing symptoms at 1 year from onset of the disease.
    Keywords post-acute COVID-19 syndrome ; risk factors ; predictors ; mortality ; COVID-19 ; Spain ; Medicine ; R
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Long-term outcomes in critically ill patients who survived COVID-19: The NUTRICOVID observational cohort study.

    Álvarez-Hernández, J / Matía-Martín, P / Cáncer-Minchot, E / Cuerda, C

    Clinical nutrition (Edinburgh, Scotland)

    2023  Volume 42, Issue 10, Page(s) 2029–2035

    Abstract: ... management and follow-up of coronavirus disease 2019 (COVID-19) patients and their long-term evolution ... This study reports on the one-year-long evolution of a cohort of COVID-19 survivors after ICU discharge ... outbreak. Retrospective and prospective data were collected from hospital admission to one year after ...

    Abstract Background & aims: Malnutrition and sarcopenia may last beyond hospital discharge, especially in patients admitted to intensive care units (ICU), having a negative impact on patient recovery and leading to disability, poor quality of life, and additional morbidity. No prior evidence is available for post-ICU management and follow-up of coronavirus disease 2019 (COVID-19) patients and their long-term evolution. This study reports on the one-year-long evolution of a cohort of COVID-19 survivors after ICU discharge, in terms of nutritional and functional status as well as health-related quality of life (HRQoL).
    Methods: A multicenter, ambispective, observational cohort study (NUTRICOVID study) was conducted in 16 public hospitals located in the Community of Madrid with COVID-19 survivors who were admitted to ICU during the first outbreak. Retrospective and prospective data were collected from hospital admission to one year after discharge. At hospital discharge and at 3, 6 and 12 months post-discharge, the following outcomes were recorded: weight, risk of malnutrition (MUST) and sarcopenia (SARC-F), medical nutrition therapy (MNT), functional status (Barthel index), and HRQoL (EQ-5D-5L).
    Results: A total of 199 patients (70.4% male, mean age [SD] of 60.7 [10.1]) were included in the study. At hospital discharge, mean weight loss was 16.4% (8.0%), whereas most patients gained weight after discharge with an increase of 16.5% (14.0%) at 12 months. The proportion of patients at high risk of malnutrition decreased from 83.2% at hospital discharge to 2.1% at 12 months. The proportion at risk of sarcopenia decreased from 86.9% at hospital discharge to 13.4% at 12 months. At hospital discharge, 69 patients received MNT by means of oral nutritional supplements (ONS) while two patients required enteral nutrition (EN). At 12 months, only 12 patients continued taking ONS, with no patients taking EN. Regarding functional status, 72.9% of patients were moderately or severely dependent at hospital discharge, whereas 87.2% showed low dependency or independency after 12 months. The EQ-VAS values increased from hospital discharge (39 [21.2]) to 6 months post-discharge and remained steady up to 12 months (72.7 [19.0]). The mean health value improved from hospital discharge (0.25 [0.41]) to 6 months post-discharge (0.80 [0.24]) and was maintained thereafter.
    Conclusions: Patients' nutritional and functional impairment at hospital discharge was high, with high dependency status and low HRQoL; however, their situation improved progressively during the 12 months following hospital discharge. Nevertheless, there is a need to define early strategies to optimize the nutritional and functional recovery of COVID-19 patients.
    MeSH term(s) Female ; Humans ; Male ; Aftercare ; Cohort Studies ; COVID-19/therapy ; Critical Illness/therapy ; Intensive Care Units ; Malnutrition/epidemiology ; Malnutrition/therapy ; Patient Discharge ; Prospective Studies ; Quality of Life ; Retrospective Studies ; Sarcopenia/epidemiology ; Sarcopenia/therapy ; Middle Aged ; Aged
    Language English
    Publishing date 2023-08-16
    Publishing country England
    Document type Observational Study ; Multicenter Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 604812-2
    ISSN 1532-1983 ; 0261-5614
    ISSN (online) 1532-1983
    ISSN 0261-5614
    DOI 10.1016/j.clnu.2023.08.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Rehospitalization indications of children hospitalized for COVID-19 infections after discharge: Should we suspect long COVID?

    Cem, Ela / Kıymet, Elif / Böncüoğlu, Elif / Şahinkaya, Şahika / Çelebi, Miray Yılmaz / Gülderen, Mustafa / Kara, Aybüke Akaslan / Özenen, Gizem Güner / Bayram, Nuri / Devrim, İlker

    The Turkish journal of pediatrics

    2023  Volume 65, Issue 4, Page(s) 583–591

    Abstract: Background: Complications that may develop in children after coronavirus disease 2019 (COVID-19 ... 19 infection are well characterized, but there is still limited data on its long-term outcomes ... infection. No other underlying cause was detected in approximately one-third of the patients ...

    Abstract Background: Complications that may develop in children after coronavirus disease 2019 (COVID-19) infections are unknown. The `Long COVID` syndrome is a new process that can also be identified in children. Therefore, in this study, the conditions that may develop in children after COVID-19 infection were discussed, and the indications for rehospitalizations were reviewed.
    Methods: This retrospective cohort study was conducted in a tertiary children`s hospital in İzmir, Türkiye. All children who were rehospitalized in the study center after discharge, and the indications for readmissions were screened.
    Results: Since the beginning of the pandemic, 777 children with COVID-19 infection were hospitalized, including 98 (12.6%) cases rehospitalized for any indication. Fifty-five (56.1%) patients were male, and 43 (43.9%) were female. The mean age of the study population was 79.3±63.5 months (1 month to 17 years). Among these 98 patients, 76 (77.6%) were rehospitalized because of the presence of their primary underlying disease, nonspecific infectious diseases unrelated to COVID-19, and the need to perform certain surgical procedures. The remaining 22 (22.4%) patients presented with symptoms such as fatigue, fever, abdominal pain, and myalgia after the COVID-19 infection. No other underlying cause was detected in approximately one-third of the patients, whose manifestations were found to be consistent with long COVID syndrome.
    Conclusions: The findings of acute COVID-19 infection are well characterized, but there is still limited data on its long-term outcomes. The majority of the study population that had no underlying disease were thought to have complications from the COVID-19 infection. Therefore, although the incidence rate of long COVID syndrome in childhood has not been revealed so far, it should be kept in mind among relevant differential diagnoses.
    MeSH term(s) Humans ; Child ; Female ; Male ; Post-Acute COVID-19 Syndrome ; COVID-19/complications ; Patient Readmission ; Patient Discharge ; Retrospective Studies
    Language English
    Publishing date 2023-09-04
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 123487-0
    ISSN 2791-6421 ; 0041-4301
    ISSN (online) 2791-6421
    ISSN 0041-4301
    DOI 10.24953/turkjped.2022.829
    Database MEDical Literature Analysis and Retrieval System OnLINE

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