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  1. Article: Erratum: Inhibition of nuclear factor kappa B pathway protects myocardial ischemia/reperfusion injury in rats under treatment with Fufang Munziq granule (Munziq).

    Maimaitiaili, Abudunaibi / Li, Junhong / Aibibula, Aili / Abudureheman, Mulati

    American journal of translational research

    2018  Volume 10, Issue 11, Page(s) 3876

    Abstract: This corrects the article on p. 77 in vol. 10, PMID: 29422995.]. ...

    Abstract [This corrects the article on p. 77 in vol. 10, PMID: 29422995.].
    Language English
    Publishing date 2018-11-15
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ZDB-ID 2471058-1
    ISSN 1943-8141
    ISSN 1943-8141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Inhibition of nuclear factor kappa B pathway protects myocardial ischemia/reperfusion injury in rats under treatment with abnormal savda munziq.

    Maimaitiaili, Abudunaibi / Li, Junhong / Aibibula, Aili / Abudureheman, Mulati

    American journal of translational research

    2018  Volume 10, Issue 1, Page(s) 77–85

    Abstract: ... investigates the regulation of nuclear factor kappa B (NF-kappa B) pathway by Fufang Munziq granule (Munziq ... in rats under Fufang Munziq granule (Munziq) [corrected] treatment. ... treated with Fufang Munziq granule (Munziq) [corrected] for 21 days before underwent IRI surgical ...

    Abstract Objective: Uighur medicine Fufang Munziq granule (Munziq) [corrected] shows cardioprotective effect in myocardial ischemia/reperfusion injury (IRI) in animal models, but the molecular mechanism of this effect is not clear. The present study investigates the regulation of nuclear factor kappa B (NF-kappa B) pathway by Fufang Munziq granule (Munziq) in IRI rat models.
    Methods: Male Sprague-Dawley rats were divided into three groups: the NF-κB gene knockout group (n = 5); the NF-κB transgenic group (n = 8); and the control group (n = 5). All rats were treated with Fufang Munziq granule (Munziq) [corrected] for 21 days before underwent IRI surgical procedure. Blood and tissue samples were collected for the RT-PCR, ELISA, western blot and other examination.
    Results: Expression of NF-κB p65mRNA and protein were down-regulated in the NF-κB knockout rats but up-regulated in the transgenic rats comparing with the controls (P<0.05). The upstream NF-κB kinase expressions, the downstream inflammatory cytokines, and the myocardial injury markers were all changed in accordance with the NF-κB gene modification (all
    Conclusion: Inhibition on NF-κB signaling pathway may alleviate IRI in rats under Fufang Munziq granule (Munziq) [corrected] treatment.
    Language English
    Publishing date 2018-01-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2471058-1
    ISSN 1943-8141
    ISSN 1943-8141
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

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