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  1. Article ; Online: Chest CT in patients suspected of COVID-19 infection: A reliable alternative for RT-PCR.

    Majidi, Hadi / Niksolat, Fatemeh

    The American journal of emergency medicine

    2020  Volume 38, Issue 12, Page(s) 2730–2732

    MeSH term(s) COVID-19/diagnostic imaging ; Humans ; Lung/diagnostic imaging ; Radiography, Thoracic ; Reverse Transcriptase Polymerase Chain Reaction ; Tomography, X-Ray Computed
    Keywords covid19
    Language English
    Publishing date 2020-04-08
    Publishing country United States
    Document type Letter
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2020.04.016
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  4. Article ; Online: Chest CT in patients suspected of COVID-19 infection

    Majidi, Hadi / Niksolat, Fatemeh

    The American Journal of Emergency Medicine ; ISSN 0735-6757

    A reliable alternative for RT-PCR

    2020  

    Keywords Emergency Medicine ; General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.ajem.2020.04.016
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Correlation Between Low-Dose Chest Computed Tomography and RT-PCR Results for the Diagnosis of COVID-19: A Report of 27,824 Cases in Tehran, Iran.

    Zali, Alireza / Sohrabi, Mohammad-Reza / Mahdavi, Ali / Khalili, Nastaran / Taheri, Morteza Sanei / Maher, Ali / Sadoughi, Mohammadmehdi / Zarghi, Afshin / Ziai, Seyed Ali / Shabestari, Abbas Arjmand / Bakhshayeshkaram, Mehrdad / Haghighatkhah, Hamidreza / Salevatipour, Babak / Abrishami, Alireza / Raoufi, Masoomeh / Dehghan, Pooneh / Bagheri, Arash Khameneh / Khoshnoud, Reza Jalili / Hanani, Khatereh

    Academic radiology

    2020  Volume 28, Issue 12, Page(s) 1654–1661

    Abstract: ... Low-dose chest CT is a safe, rapid and reliable alternative to RT-PCR for the diagnosis of COVID-19 ... patients with clinical suspicion of COVID-19 infection who underwent unenhanced low-dose chest CT from 20 ... the diagnostic performance of chest computed tomography (CT) as an alternative to RT-PCR in patients ...

    Abstract Rationale and objectives: Real-time polymerase chain reaction (RT-PCR) remains the gold standard for confirmation of Coronavirus Disease 2019 (COVID-19) despite having many disadvantages. Here, we investigated the diagnostic performance of chest computed tomography (CT) as an alternative to RT-PCR in patients with clinical suspicion of COVID-19 infection.
    Methods: In this descriptive cross-sectional study, 27,824 patients with clinical suspicion of COVID-19 infection who underwent unenhanced low-dose chest CT from 20 February, 2020 to 21 May, 2020 were evaluated. Patients were recruited from seven specifically designated hospitals for patients with COVID-19 infection affiliated to Shahid Beheshti University of Medical Sciences. In each hospital, images were interpreted by two independent radiologists. CT findings were considered as positive/negative for COVID-19 infection based on RSNA diagnostic criteria. Then, the correlation between the number of daily positive chest CT scans and number of daily PCR-confirmed cases and COVID-19-related deaths in Tehran province during this three-month period was assessed. The trends of admission rate and patients with positive CT scans were also evaluated.
    Results: A strong positive correlation between the numbers of daily positive CT scans and daily PCR-confirmed COVID-19 cases (r = 0.913, p < 0.001) was observed. Furthermore, in hospitals located in regions with a lower socioeconomic status, the admission rate and number of positive cases within this three-month period was higher as compared to other hospitals.
    Conclusion: Low-dose chest CT is a safe, rapid and reliable alternative to RT-PCR for the diagnosis of COVID-19 in high-prevalence regions. In addition, our study provides further evidence for considering patients' socioeconomic status as an important risk factor for COVID-19.
    MeSH term(s) COVID-19 ; Cross-Sectional Studies ; Humans ; Iran/epidemiology ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2 ; Sensitivity and Specificity ; Tomography, X-Ray Computed
    Keywords covid19
    Language English
    Publishing date 2020-09-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1355509-1
    ISSN 1878-4046 ; 1076-6332
    ISSN (online) 1878-4046
    ISSN 1076-6332
    DOI 10.1016/j.acra.2020.09.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Correlation Between Low-Dose Chest Computed Tomography and RT-PCR Results for the Diagnosis of COVID-19: A Report of 27,824 Cases in Tehran, Iran

    Zali, Alireza / Sohrabi, Mohammad-Reza / Mahdavi, Ali / Khalili, Nastaran / Taheri, Morteza Sanei / Maher, Ali / Sadoughi, Mohammadmehdi / Zarghi, Afshin / Ziai, Seyed Ali / Shabestari, Abbas Arjmand / Bakhshayeshkaram, Mehrdad / Haghighatkhah, Hamidreza / Salevatipour, Babak / Abrishami, Alireza / Raoufi, Masoomeh / Dehghan, Pooneh / Bagheri, Arash Khameneh / Khoshnoud, Reza Jalili / Hanani, Khatereh

    Acad. radiol

    Abstract: ... dose chest CT is a safe, rapid and reliable alternative to RT-PCR for the diagnosis of COVID-19 in high ... patients with clinical suspicion of COVID-19 infection who underwent unenhanced low-dose chest CT from 20 ... the diagnostic performance of chest computed tomography (CT) as an alternative to RT-PCR in patients ...

    Abstract RATIONALE AND OBJECTIVES: Real-time polymerase chain reaction (RT-PCR) remains the gold standard for confirmation of Coronavirus Disease 2019 (COVID-19) despite having many disadvantages. Here, we investigated the diagnostic performance of chest computed tomography (CT) as an alternative to RT-PCR in patients with clinical suspicion of COVID-19 infection. METHODS: In this descriptive cross-sectional study, 27,824 patients with clinical suspicion of COVID-19 infection who underwent unenhanced low-dose chest CT from 20 February, 2020 to 21 May, 2020 were evaluated. Patients were recruited from seven specifically designated hospitals for patients with COVID-19 infection affiliated to Shahid Beheshti University of Medical Sciences. In each hospital, images were interpreted by two independent radiologists. CT findings were considered as positive/negative for COVID-19 infection based on RSNA diagnostic criteria. Then, the correlation between the number of daily positive chest CT scans and number of daily PCR-confirmed cases and COVID-19-related deaths in Tehran province during this three-month period was assessed. The trends of admission rate and patients with positive CT scans were also evaluated. RESULTS: A strong positive correlation between the numbers of daily positive CT scans and daily PCR-confirmed COVID-19 cases (r = 0.913, p < 0.001) was observed. Furthermore, in hospitals located in regions with a lower socioeconomic status, the admission rate and number of positive cases within this three-month period was higher as compared to other hospitals. CONCLUSION: Low-dose chest CT is a safe, rapid and reliable alternative to RT-PCR for the diagnosis of COVID-19 in high-prevalence regions. In addition, our study provides further evidence for considering patients' socioeconomic status as an important risk factor for COVID-19.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #834162
    Database COVID19

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