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Article: Community Antibiotic Use at the Population Level During the SARS-CoV-2 Pandemic in British Columbia, Canada.

Mamun, Abdullah A / Saatchi, Ariana / Xie, Max / Lishman, Hannah / Blondel-Hill, Edith / Marra, Fawziah / Patrick, David M

Open forum infectious diseases

2021  Volume 8, Issue 6, Page(s) ofab185

Abstract: ... In British Columbia, Canada, overall and RTI-specific monthly antibiotic prescription rates declined significantly ... of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the resulting control measures on community prescribing.: Methods ... at the population level and compare these rates over time against historical averages to identify the effect ...

Abstract Background: The objective of this study was to examine the aggregate rates of antibiotic use at the population level and compare these rates over time against historical averages to identify the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the resulting control measures on community prescribing.
Methods: We collected antibiotic prescriptions and physician office visits from January 1, 2016, to July 21, 2020. We calculated monthly prescription rates stratified by sex, age group, profession, diagnosis type, and antibiotic class. We looked at monthly prescription rate as a moving average over time. Using the interrupted time series analysis method, we estimated the changes in prescription rates after March 2020.
Results: The moving average of overall monthly prescription rates during January-June 2020 was below the minimum of the historical years' moving averages (2016-2019). We observed a >30% reduction in overall monthly prescription rates in April, May, and July of 2020 compared with the same months of 2019. We observed that overall monthly prescription rates experienced a significant level change of -12.79 (
Conclusions: In British Columbia, Canada, overall and RTI-specific monthly antibiotic prescription rates declined significantly during April-July 2020 compared with the same months in prepandemic years.
Language English
Publishing date 2021-04-13
Publishing country United States
Document type Journal Article
ZDB-ID 2757767-3
ISSN 2328-8957
ISSN 2328-8957
DOI 10.1093/ofid/ofab185
Database MEDical Literature Analysis and Retrieval System OnLINE

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