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Article ; Online: Blood group type A secretors are associated with a higher risk of COVID-19 cardiovascular disease complications.

Mankelow, Tosti J / Singleton, Belinda K / Moura, Pedro L / Stevens-Hernandez, Christian J / Cogan, Nicola M / Gyorffy, Gyongyver / Kupzig, Sabine / Nichols, Luned / Asby, Claire / Pooley, Jennifer / Ruffino, Gabriella / Hosseini, Faroakh / Moghaddas, Fiona / Attwood, Marie / Noel, Alan / Cooper, Alex / Arnold, David T / Hamilton, Fergus / Hyams, Catherine /
Finn, Adam / Toye, Ashley M / Anstee, David J

EJHaem

2021  Volume 2, Issue 2, Page(s) 175–187

Abstract: ... was associated with COVID-19 severity. We investigated secretor status because expression of ABO ... The SARS-CoV-2 virus causes COVID-19, an infection capable of causing severe disease and death ... but which can also be asymptomatic or oligosymptomatic. We investigated whether ABO blood group or secretor status ...

Abstract The SARS-CoV-2 virus causes COVID-19, an infection capable of causing severe disease and death but which can also be asymptomatic or oligosymptomatic. We investigated whether ABO blood group or secretor status was associated with COVID-19 severity. We investigated secretor status because expression of ABO glycans on secreted proteins and non-erythroid cells are controlled by a fucosyltransferase (FUT2), and inactivating FUT2 mutations result in a non-secretor phenotype which protects against some viral infections. Data combined from healthcare records and our own laboratory tests (
Language English
Publishing date 2021-04-02
Publishing country United States
Document type Journal Article
ISSN 2688-6146
ISSN (online) 2688-6146
DOI 10.1002/jha2.180
Database MEDical Literature Analysis and Retrieval System OnLINE

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