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  1. Article ; Online: Challenges Faced by Solid Organ Transplant Recipients During the COVID-19 Pandemic in France: Historical Insights and Key Takeaways.

    Benotmane, Ilies / Legendre, Christophe / Caillard, Sophie

    Transplantation

    2024  Volume 108, Issue 4, Page(s) 819–822

    MeSH term(s) Humans ; COVID-19 ; Pandemics ; France/epidemiology ; Organ Transplantation/adverse effects
    Language English
    Publishing date 2024-03-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000004924
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Excess Mortality Among Solid Organ Transplant Recipients in the United States During the COVID-19 Pandemic.

    Clarke, Jacob A / Wiemken, Timothy L / Korenblat, Kevin M

    Transplantation

    2022  Volume 106, Issue 12, Page(s) 2399–2407

    Abstract: ... since the start of solid organ transplantation (SOT). Prior studies have demonstrated that SOT recipients are ... the cumulative excess mortality in SOT recipients during the first 20 mo of the pandemic.: Results: Compared ... higher in Black (236.8; CI, 186.1-287) and Hispanic (256.9; CI, 208.1-305.2) organ recipients compared ...

    Abstract Background: The COVID-19 pandemic is the first sustained respiratory disease pandemic to arise since the start of solid organ transplantation (SOT). Prior studies have demonstrated that SOT recipients are at greater risk for severe complications of infection and are less likely to respond to vaccination.
    Methods: The Scientific Registry of Transplant Recipients Standard Analysis Files was used to assess the cumulative excess mortality in SOT recipients during the first 20 mo of the pandemic.
    Results: Compared with excess mortality rates in the US population (25.9 deaths/10 000; confidence interval [CI], 10.9-41.1), the excess mortality per 10 000 was higher in all SOT groups: kidney (188.5; CI, 150.7-225.6), lung (173.6; CI, 17-334.7), heart (123.7; CI, 56-191.4), and liver (105.1; CI, 64.6-146). The higher rates persisted even with attempts to control for population age structure and renal allograft failure. Excess mortality was also higher in Black (236.8; CI, 186.1-287) and Hispanic (256.9; CI, 208.1-305.2) organ recipients compared with other racial and ethnic groups in the Scientific Registry of Transplant Recipients and compared with the Black and Hispanic populations in the United States.
    Conclusions: Studies of excess mortality provide insight into the health and survival of specialized populations like SOT recipients during major health events like the COVID-19 pandemic.
    MeSH term(s) United States/epidemiology ; Humans ; Transplant Recipients ; COVID-19 ; Pandemics ; Kidney Transplantation/adverse effects ; Organ Transplantation/adverse effects
    Language English
    Publishing date 2022-11-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000004341
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Solid organ transplant recipients during COVID-19 pandemic.

    Marcault, Clémence / Fodil, Sofiane / Dupont, Thibault / Darmon, Michael / Azoulay, Elie

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

    2020  Volume 20, Issue 10, Page(s) 2960–2961

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Organ Transplantation ; Pandemics ; Pneumonia, Viral ; Preliminary Data ; Severe acute respiratory syndrome-related coronavirus ; SARS-CoV-2 ; Transplant Recipients
    Keywords covid19
    Language English
    Publishing date 2020-06-30
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2060594-8
    ISSN 1600-6143 ; 1600-6135
    ISSN (online) 1600-6143
    ISSN 1600-6135
    DOI 10.1111/ajt.16126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A retrospective analysis of rates of dermatology follow-up and new skin cancer diagnosis among solid organ transplant recipients during the COVID-19 pandemic.

    Saranath, Ritika / Fernandez, Braulio / Gomez, Jacob / Miller, Melanie / Novack, Danielle / Parvathala, Neha / Shah, Ema / Wong-Michalak, Shannon / Rodman, Jack / Fong, Michael W / Ganesh, Sivagini / Han, Hyosun / In, Gino K / Kahn, Jeffrey / Liebler, Janice / Maw, Thin Thin / Miller, Kimberly / Smogorzewski, Miroslaw / Hu, Jenny /
    Ngo, Binh / Ahronowitz, Iris

    JAAD international

    2022  Volume 10, Page(s) 53–54

    Language English
    Publishing date 2022-11-17
    Publishing country United States
    Document type Journal Article
    ISSN 2666-3287
    ISSN (online) 2666-3287
    DOI 10.1016/j.jdin.2022.10.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Changing trends in mortality among solid organ transplant recipients hospitalized for COVID-19 during the course of the pandemic.

    Heldman, Madeleine R / Kates, Olivia S / Safa, Kassem / Kotton, Camille N / Georgia, Sarah J / Steinbrink, Julie M / Alexander, Barbara D / Hemmersbach-Miller, Marion / Blumberg, Emily A / Multani, Ashrit / Haydel, Brandy / La Hoz, Ricardo M / Moni, Lisset / Condor, Yesabeli / Flores, Sandra / Munoz, Carlos G / Guitierrez, Juan / Diaz, Esther I / Diaz, Daniela /
    Vianna, Rodrigo / Guerra, Giselle / Loebe, Matthias / Rakita, Robert M / Malinis, Maricar / Azar, Marwan M / Hemmige, Vagish / McCort, Margaret E / Chaudhry, Zohra S / Singh, Pooja P / Hughes Kramer, Kailey / Velioglu, Arzu / Yabu, Julie M / Morillis, Jose A / Mehta, Sapna A / Tanna, Sajal D / Ison, Michael G / Derenge, Ariella C / van Duin, David / Maximin, Adrienne / Gilbert, Carlene / Goldman, Jason D / Lease, Erika D / Fisher, Cynthia E / Limaye, Ajit P

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

    2021  Volume 22, Issue 1, Page(s) 279–288

    Abstract: ... Mortality trends specifically in solid organ transplant recipients (SOTR) are unknown. Using data ... Mortality among patients hospitalized for COVID-19 has declined over the course of the pandemic ... from a multicenter registry of SOTR hospitalized for COVID-19, we compared 28-day mortality between early 2020 (March ...

    Abstract Mortality among patients hospitalized for COVID-19 has declined over the course of the pandemic. Mortality trends specifically in solid organ transplant recipients (SOTR) are unknown. Using data from a multicenter registry of SOTR hospitalized for COVID-19, we compared 28-day mortality between early 2020 (March 1, 2020-June 19, 2020) and late 2020 (June 20, 2020-December 31, 2020). Multivariable logistic regression was used to assess comorbidity-adjusted mortality. Time period of diagnosis was available for 1435/1616 (88.8%) SOTR and 971/1435 (67.7%) were hospitalized: 571/753 (75.8%) in early 2020 and 402/682 (58.9%) in late 2020 (p < .001). Crude 28-day mortality decreased between the early and late periods (112/571 [19.6%] vs. 55/402 [13.7%]) and remained lower in the late period even after adjusting for baseline comorbidities (aOR 0.67, 95% CI 0.46-0.98, p = .016). Between the early and late periods, the use of corticosteroids (≥6 mg dexamethasone/day) and remdesivir increased (62/571 [10.9%] vs. 243/402 [61.5%], p < .001 and 50/571 [8.8%] vs. 213/402 [52.2%], p < .001, respectively), and the use of hydroxychloroquine and IL-6/IL-6 receptor inhibitor decreased (329/571 [60.0%] vs. 4/492 [1.0%], p < .001 and 73/571 [12.8%] vs. 5/402 [1.2%], p < .001, respectively). Mortality among SOTR hospitalized for COVID-19 declined between early and late 2020, consistent with trends reported in the general population. The mechanism(s) underlying improved survival require further study.
    MeSH term(s) COVID-19 ; Humans ; Organ Transplantation/adverse effects ; Pandemics ; SARS-CoV-2 ; Transplant Recipients
    Language English
    Publishing date 2021-10-07
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2060594-8
    ISSN 1600-6143 ; 1600-6135
    ISSN (online) 1600-6143
    ISSN 1600-6135
    DOI 10.1111/ajt.16840
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Solid organ transplant recipients during COVID19 pandemic

    Marcault, Clémence / Fodil, Sofiane / Dupont, Thibault / Darmon, Michael / Azoulay, Elie

    American Journal of Transplantation ; ISSN 1600-6135 1600-6143

    2020  

    Keywords Immunology and Allergy ; Pharmacology (medical) ; Transplantation ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1111/ajt.16126
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Zero health-care-associated respiratory viral infections among solid organ transplant recipients: Infection prevention outcomes during COVID-19 pandemic.

    Wee, Liang E / Tan, Jing Y / Chung, Shimin J / Conceicao, Edwin P / Hock Tan, Ban / Venkatachalam, Indumathi

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

    2021  Volume 21, Issue 6, Page(s) 2311–2313

    MeSH term(s) COVID-19 ; Humans ; Organ Transplantation/adverse effects ; Pandemics ; SARS-CoV-2 ; Transplant Recipients
    Language English
    Publishing date 2021-02-17
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2060594-8
    ISSN 1600-6143 ; 1600-6135
    ISSN (online) 1600-6143
    ISSN 1600-6135
    DOI 10.1111/ajt.16499
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Health-related quality of life, uncertainty and coping strategies in solid organ transplant recipients during shielding for the COVID-19 pandemic.

    McKay, Siobhan C / Lembach, Hanns / Hann, Angus / Okoth, Kelvin / Anderton, Joy / Nirantharakumar, Krishnarajah / Magill, Laura / Torlinska, Barbara / Armstrong, Matthew / Mascaro, Jorge / Inston, Nicholas / Pinkney, Thomas / Ranasinghe, Aaron / Borrows, Richard / Ferguson, James / Isaac, John / Calvert, Melanie / Perera, M Thamara P R / Hartog, Hermien

    Transplant international : official journal of the European Society for Organ Transplantation

    2021  Volume 34, Issue 11, Page(s) 2122–2137

    Abstract: ... uncertainty and coping behaviours in solid organ transplant (SOT) recipients during the COVID-19 pandemic ... to improve HRQoL in SOT recipients during the pandemic. ... in SOT recipients during strict isolation. These findings may allow identification of strategies ...

    Abstract Strict isolation of vulnerable individuals has been a strategy implemented by authorities to protect people from COVID-19. Our objective was to investigate health-related quality of life (HRQoL), uncertainty and coping behaviours in solid organ transplant (SOT) recipients during the COVID-19 pandemic. A cross-sectional survey of adult SOT recipients undergoing follow-up at our institution was performed. Perceived health status, uncertainty and coping strategies were assessed using the EQ-5D-5L, Short-form Mishel Uncertainty in Illness Scale (SF-MUIS) and Brief Cope, respectively. Interactions with COVID-19 risk perception, access to health care, demographic and clinical variables were assessed. The survey was completed by 826 of 3839 (21.5%) invited participants. Overall, low levels of uncertainty in illness were reported, and acceptance was the major coping strategy (92%). Coping by acceptance, feeling protected, self-perceived susceptibility to COVID-19 were associated with lower levels of uncertainty. Health status index scores were significantly lower for those with mental health illness, compromised access to health care, a perceived high risk of severe COVID-19 infection and higher levels of uncertainty. A history of mental health illness, risk perceptions, restricted healthcare access, uncertainty and coping strategies was associated with poorer HRQoL in SOT recipients during strict isolation. These findings may allow identification of strategies to improve HRQoL in SOT recipients during the pandemic.
    MeSH term(s) Adaptation, Psychological ; Adult ; COVID-19 ; Cross-Sectional Studies ; Humans ; Organ Transplantation ; Pandemics ; Quality of Life ; SARS-CoV-2 ; Transplant Recipients ; Uncertainty
    Language English
    Publishing date 2021-09-16
    Publishing country Switzerland
    Document type Journal Article ; Comment
    ZDB-ID 639435-8
    ISSN 1432-2277 ; 0934-0874
    ISSN (online) 1432-2277
    ISSN 0934-0874
    DOI 10.1111/tri.14010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Return to School for Pediatric Solid Organ Transplant Recipients in the United States During the COVID-19 Pandemic: Expert Opinion on Key Considerations and Best Practices

    Downes, Kevin J / Danziger-Isakov, Lara A / Cousino, Melissa K / Green, Michael / Michaels, Marian G / Muller, William J / Orscheln, Rachel C / Sharma, Tanvi S / Statler, Victoria A / Wattier, Rachel L / Ardura, Monica I

    Journal of the Pediatric Infectious Diseases Society

    Abstract: The COVID-19 pandemic has created many challenges for pediatric solid organ transplant (SOT ... to school re-entry specific to pediatric SOT recipients. Although data are limited, and the COVID-19 ... recipients and their families. As the pandemic persists, patients and their families struggle to identify ...

    Abstract The COVID-19 pandemic has created many challenges for pediatric solid organ transplant (SOT) recipients and their families. As the pandemic persists, patients and their families struggle to identify the best and safest practices for resuming activities as areas re-open. In particular, decisions about returning to school remain difficult. We assembled a team of pediatric infectious diseases, transplant infectious diseases, public health, transplant psychology, and infection prevention and control specialists to address the primary concerns about school re-entry for pediatric SOT recipients in the United States. Based on available literature and guidance from national organizations, we generated consensus statements pertaining to school re-entry specific to pediatric SOT recipients. Although data are limited, and the COVID-19 pandemic highly dynamic, our goal was to create a framework from which providers and caregivers can identify the most important considerations for each pediatric SOT recipient to promote a safe return to school this fall.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #693940
    Database COVID19

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