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  1. Article: Biochemical and morphological aspects of bone tissue in chronic renal failure.

    Maschio, G / Bonucci, E / Mioni, G / D'Angelo, A / Ossi, E / Valvo, E / Lupo, A

    Nephron

    1974  Volume 12, Issue 6, Page(s) 437–448

    MeSH term(s) Adult ; Biopsy ; Bone Marrow Diseases/pathology ; Bone Matrix/pathology ; Bone Resorption/pathology ; Bone and Bones/analysis ; Bone and Bones/pathology ; Calcium/analysis ; Diet Therapy ; Dietary Proteins ; Humans ; Hyperparathyroidism/pathology ; Intestinal Absorption ; Kidney Failure, Chronic/pathology ; Magnesium/analysis ; Microscopy, Electron ; Middle Aged ; Nitrogen/analysis ; Osteoblasts ; Osteoclasts ; Osteomalacia/pathology ; Phosphates/analysis ; Phosphorus ; Protein Deficiency/complications ; Uremia/pathology
    Chemical Substances Dietary Proteins ; Phosphates ; Phosphorus (27YLU75U4W) ; Magnesium (I38ZP9992A) ; Nitrogen (N762921K75) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 1974
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 207121-6
    ISSN 1423-0186 ; 2235-3186 ; 1660-8151 ; 0028-2766
    ISSN (online) 1423-0186 ; 2235-3186
    ISSN 1660-8151 ; 0028-2766
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 169: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Biochemical and Morphological Aspects of Bone Tissue in Chronic Renal Failure

    Maschio, G. / Bonucci, E. / Mioni, G. / D’Angelo, A. / Ossi, E. / Valvo, E. / Lupo, A.

    Nephron

    1974  Volume 12, Issue 6, Page(s) 437–448

    Abstract: A biochemical and bone biopsy investigation was made in 30 patients with chronic renal failure ... associated with increased osteoclastic activity and some degree of bone resorption and bone ... marrow fibrosis in 13% of the patients. In the remaining patients (27%) the bone tissue was substantially normal ...

    Abstract A biochemical and bone biopsy investigation was made in 30 patients with chronic renal failure. Osteomalacia was the main pathological feature in 60% of the patients. Both optical and electron microscopic studies showed that the matrix adjacent to the osteoblasts was not mineralized. Osteomalacia was associated with increased osteoclastic activity and some degree of bone resorption and bone marrow fibrosis in 13% of the patients. In the remaining patients (27%) the bone tissue was substantially normal. The bone calcium content was lower than normal in uraemic patients, whereas a significant increase in magnesium content was observed.The low frequency of the pathological features specific for hyperparathyroidism may be explained by the low-protein, low-phosphorus diets usually followed by the patients. The decrease in bone calcium content depends probably on the reduction in its intestinal absorption and partly on the protein depletion usually observed in patients on low-protein diets. Furthermore, the bone magnesium excess may be regarded as a potentiating factor of bone calcium deficiency.
    Keywords Bone composition ; Optical microscopy ; Electron microscopy ; Chronic renal failure
    Language English
    Publisher S. Karger AG
    Publishing place Basel
    Publishing country Switzerland
    Document type Article ; Online
    ZDB-ID 207121-6
    ISSN 1423-0186 ; 0028-2766 ; 1660-8151 ; 0028-2766 ; 1660-8151
    ISSN (online) 1423-0186
    ISSN 0028-2766 ; 1660-8151
    DOI 10.1159/000180381
    Database Karger publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 169: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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