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  1. Article ; Online: Using SARS-CoV-2 Antibody Testing in COVID-19 Research.

    Amraotkar, Alok R / Keith, Rachel J / Palmer, Kenneth E / Bhatnagar, Aruni

    The American journal of medicine

    2023  Volume 136, Issue 6, Page(s) 501–503

    MeSH term(s) Humans ; COVID-19/diagnosis ; SARS-CoV-2 ; Antibodies, Viral ; Immunoglobulin G ; COVID-19 Testing
    Chemical Substances Antibodies, Viral ; Immunoglobulin G
    Language English
    Publishing date 2023-02-12
    Publishing country United States
    Document type Editorial ; Research Support, U.S. Gov't, P.H.S. ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2023.02.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Antibody Testing for COVID-19.

    Grenache, David G / Sever, Cordelia / Mathur, Gagan / Mathur, Sweta

    American journal of clinical pathology

    2020  Volume 154, Issue 3, Page(s) 425–426

    MeSH term(s) COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Humans
    Keywords covid19
    Language English
    Publishing date 2020-06-09
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2944-0
    ISSN 1943-7722 ; 0002-9173
    ISSN (online) 1943-7722
    ISSN 0002-9173
    DOI 10.1093/ajcp/aqaa110
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Antibody Testing for COVID-19.

    Mathur, Gagan / Mathur, Sweta

    American journal of clinical pathology

    2020  Volume 154, Issue 1, Page(s) 1–3

    MeSH term(s) Antibodies, Viral/blood ; Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Humans ; Pandemics ; Pneumonia, Viral/diagnosis ; SARS-CoV-2 ; United States ; United States Food and Drug Administration
    Chemical Substances Antibodies, Viral
    Keywords covid19
    Language English
    Publishing date 2020-04-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2944-0
    ISSN 1943-7722 ; 0002-9173
    ISSN (online) 1943-7722
    ISSN 0002-9173
    DOI 10.1093/ajcp/aqaa082
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  4. Article ; Online: COVID-19 Antibody Testing: Facts vs. Fallacies.

    Afzal, Nayab

    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

    2022  Volume 32, Issue 6, Page(s) 826–226

    Abstract: Null. ...

    Abstract Null.
    MeSH term(s) COVID-19 ; Humans
    Language English
    Publishing date 2022-01-04
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 2276646-7
    ISSN 1681-7168 ; 1022-386X
    ISSN (online) 1681-7168
    ISSN 1022-386X
    DOI 10.29271/jcpsp.2022.06.826
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  5. Article ; Online: COVID-19 antibody testing

    Zolton, Jessica R.

    Global Reproductive Health

    future directions

    2020  Volume 5, Issue 3, Page(s) e45–e45

    Keywords covid19
    Language English
    Publisher Ovid Technologies (Wolters Kluwer Health)
    Publishing country us
    Document type Article ; Online
    ISSN 2473-3709
    DOI 10.1097/grh.0000000000000045
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: COVID-19 antibody testing

    Gray, C M / Peter, J / Mendelson, M / Madhi, S / Blackburn, J M

    South African Medical Journal; Vol 110, No; 837-841 ; 2078-5135 ; 0256-9574

    From hype to immunological reality

    2020  Volume 9

    Abstract: ... infection and the impact of this on the sensitivity and specificity of COVID-19 antibody tests made ... applications for current COVID-19 antibody tests in identifying acute infections, in confirming recent or past ... We conclude with guidance on where current COVID-19 antibody tests can make a genuine impact in the pandemic. ...

    Abstract The potential role for serological tests in the current COVID-19 pandemic has generated very considerable recent interest across many sectors worldwide, inter alia pathologists seeking additional weapons for their armoury of diagnostic tests; epidemiologists seeking tools to gain seroprevalence data that will inform improved models of the spread of disease; research scientists seeking tools to study the natural history of COVID-19 disease; vaccine developers seeking tools to assess vaccine efficacy in clinical trials; and companies and governments seeking tools to aid return-to-work decision-making. However, much of the local debate to date has centred on questions surrounding whether regulatory approval processes are limiting access to serological tests, and has not paused to consider the intrinsically limiting impact of underlying fundamental biology and immunology on where and how different COVID-19 serological tests can usefully be deployed in the response to the current pandemic. We review, from an immunological perspective, recent experimental evidence on the time-dependency of adaptive immune responses following SARS-CoV-2 infection and the impact of this on the sensitivity and specificity of COVID-19 antibody tests made at different time points post infection. We interpret this scientific evidence in terms of mooted clinical applications for current COVID-19 antibody tests in identifying acute infections, in confirming recent or past infections at the individual and population level, and in detecting re-infection and protective immunity. We conclude with guidance on where current COVID-19 antibody tests can make a genuine impact in the pandemic.
    Keywords Viral diseases ; Virology ; Diagnosis ; Diagnostics ; Basic medical science ; covid19
    Subject code 306
    Language English
    Publishing date 2020-07-27
    Publisher South African Medical Association
    Publishing country za
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: COVID-19 Antibody Testing in Healthcare Workers in Arkansas.

    Joshi, Manish / Theus, John / Joshi, Anita / Burns, Matthew / Bartter, Thaddeus

    Cureus

    2023  Volume 15, Issue 11, Page(s) e48511

    Abstract: ... Of the 37 people, 32 had a history of COVID-19 infection proven ... availability. Methods The Central Arkansas Veterans Healthcare System offered SARS-CoV-2 antibody testing prior ... Arkansas Veterans Healthcare System HCWs who had undergone SARS-CoV-2 antibody testing from July 1, 2020 ...

    Abstract Introduction Seroprevalence surveys can estimate the cumulative incidence of SARS-CoV-2 infection in a symptom-independent manner, offering valuable data, including herd immunity, that can inform national and local public health policies. To our knowledge, there have been no large studies reporting seroprevalence in healthcare workers (HCWs) in the state of Arkansas. The objective of this study is to measure SARS-CoV-2 seroprevalence in HCWs in a large tertiary-care healthcare system prior to vaccine availability. Methods The Central Arkansas Veterans Healthcare System offered SARS-CoV-2 antibody testing prior to the widespread availability of vaccines. After Central Arkansas Veterans Healthcare System institutional review board (IRB) approval had been obtained, a retrospective chart review was used to identify all Central Arkansas Veterans Healthcare System HCWs who had undergone SARS-CoV-2 antibody testing from July 1, 2020, to September 30, 2020. Descriptive analysis was performed using Microsoft Excel (Microsoft Corporation, Redmond, Washington, United States). Correlation and regression tests were performed using SAS 9.4 software (SAS Institute Inc., Cary, NC). Results Over the study interval, 170 healthcare personnel had undergone SARS-CoV-2 anti-spike IgG antibody testing. Thirty-seven (21.8%) had positive antibody results. The 37 individuals were mostly women (94.5%), and the average age of the group was 47 years (range 29-69 years). The median antibody titers for those testing positive for antibodies were 10.8 units (range 1.1-58.5). Of the 37 people, 32 had a history of COVID-19 infection proven by reverse transcriptase polymerase chain reaction (RT-PCR). Conclusion Serologic testing is feasible for healthcare workers to document an immune response to a prior infection. In this study of HCWs, the rate of positivity among those tested was 21.8%. Data that do not incorporate the cohort of patients with prior infections will underestimate the impact of prior infections on herd immunity statistics and may misinform public policy.
    Language English
    Publishing date 2023-11-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.48511
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  8. Article ; Online: Audio Interview: Understanding Antibody Testing in Covid-19.

    Rubin, Eric J / Baden, Lindsey R / Morrissey, Stephen

    The New England journal of medicine

    2020  Volume 383, Issue 10, Page(s) e85

    MeSH term(s) Antibodies, Viral/analysis ; Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Humans ; Pandemics ; Pneumonia, Viral/diagnosis ; SARS-CoV-2
    Chemical Substances Antibodies, Viral
    Keywords covid19
    Language English
    Publishing date 2020-09-02
    Publishing country United States
    Document type Editorial ; Interview ; Video-Audio Media
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMe2028992
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  9. Article ; Online: COVID-19 antibody testing: future directions.

    Zolton, Jessica R

    Global reproductive health

    2020  Volume 5

    Abstract: ... contact tracing and antibody testing will likely be incorporated to slow the spread of COVID-19. However, future ... The novel coronavirus disease 2019 (COVID-19) has rapidly spread around the world, impacting ... research is needed to determine if the presence of COVID-19 antibodies offers immunity. ...

    Abstract The novel coronavirus disease 2019 (COVID-19) has rapidly spread around the world, impacting every aspect of life. Valuable research is currently being conducted to understand disease transmission, detection, and treatment. As countries begin to relax policies aimed to reduce disease transmission, contact tracing and antibody testing will likely be incorporated to slow the spread of COVID-19. However, future research is needed to determine if the presence of COVID-19 antibodies offers immunity.
    Language English
    Publishing date 2020-09-02
    Publishing country United States
    Document type Journal Article
    ISSN 2473-3709
    ISSN (online) 2473-3709
    DOI 10.1097/GRH.0000000000000045
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