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  1. Article: Gene expression profiling of human fibrocytic myeloid-derived suppressor cells (f-MDSCs).

    Mazza, Emilia Maria Cristina / Zoso, Alessia / Mandruzzato, Susanna / Bronte, Vincenzo / Serafini, Paolo / Inverardi, Luca / Bicciato, Silvio

    Genomics data

    2014  Volume 2, Page(s) 389–392

    Abstract: Myeloid-derived suppressor cells (MDSCs) have been shown to control self-reactive and anti-graft ... of myeloid suppressor cells, named fibrocytic MDSC (f-MDSC), which are differentiated ... effector T-cells in autoimmunity and transplantation, but their therapeutic use is limited by their scarce ...

    Abstract Myeloid-derived suppressor cells (MDSCs) have been shown to control self-reactive and anti-graft effector T-cells in autoimmunity and transplantation, but their therapeutic use is limited by their scarce availability in the peripheral blood of tumor-free donors. We isolated and characterized a novel population of myeloid suppressor cells, named fibrocytic MDSC (f-MDSC), which are differentiated from umbilical cord blood (UCB) precursors (Zoso et al., 2014). This MDSC subset promotes regulatory T-cell expansion and induces normoglycemia in a xenogeneic model of type 1 diabetes. Here we describe in details the experimental design and the bioinformatics analyses of the gene expression dataset used to investigate the molecular mechanisms at the base of MDSC tolerogenic and suppressive properties. We also provide an R code to easily access the data and perform the quality controls and basic analyses relevant to this dataset. Raw and pre-processed data are available at Gene Expression Omnibus under accession GSE52376.
    Language English
    Publishing date 2014-10-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2751131-5
    ISSN 2213-5960
    ISSN 2213-5960
    DOI 10.1016/j.gdata.2014.10.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Gene expression profiling of human fibrocytic myeloid-derived suppressor cells (f-MDSCs)

    Mazza, Emilia Maria Cristina / Zoso, Alessia / Mandruzzato, Susanna / Bronte, Vincenzo / Serafini, Paolo / Inverardi, Luca / Bicciato, Silvio

    Genomics Data. 2014 Dec., v. 2

    2014  

    Abstract: Myeloid-derived suppressor cells (MDSCs) have been shown to control self-reactive and anti-graft ... of myeloid suppressor cells, named fibrocytic MDSC (f-MDSC), which are differentiated ... effector T-cells in autoimmunity and transplantation, but their therapeutic use is limited by their scarce ...

    Abstract Myeloid-derived suppressor cells (MDSCs) have been shown to control self-reactive and anti-graft effector T-cells in autoimmunity and transplantation, but their therapeutic use is limited by their scarce availability in the peripheral blood of tumor-free donors. We isolated and characterized a novel population of myeloid suppressor cells, named fibrocytic MDSC (f-MDSC), which are differentiated from umbilical cord blood (UCB) precursors (Zoso et al., 2014). This MDSC subset promotes regulatory T-cell expansion and induces normoglycemia in a xenogeneic model of type 1 diabetes. Here we describe in details the experimental design and the bioinformatics analyses of the gene expression dataset used to investigate the molecular mechanisms at the base of MDSC tolerogenic and suppressive properties. We also provide an R code to easily access the data and perform the quality controls and basic analyses relevant to this dataset. Raw and pre-processed data are available at Gene Expression Omnibus under accession GSE52376.
    Keywords autoimmunity ; bioinformatics ; blood glucose ; data collection ; experimental design ; gene expression ; gene expression regulation ; humans ; insulin-dependent diabetes mellitus ; models ; suppressor cells ; umbilical cord
    Language English
    Dates of publication 2014-12
    Size p. 389-392.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 2751131-5
    ISSN 2213-5960
    ISSN 2213-5960
    DOI 10.1016/j.gdata.2014.10.018
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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