Article: Virus susceptibility of mouse hemopoietic cells in vitro: inhibition of granulocyte-macrophage precursor cells by Newcastle disease virus.
1975 Volume 11, Issue 3, Page(s) 424–428
Abstract: ... REO3), influenza virus (FLU), and Newcastle disease virus (NDV) then assayed for granulocyte-macrophage ... Normal mouse bone marrow cells were exposed to encephalomyocarditis virus (EMC), reovirus type 3 ... inhibition was associated with fully infective virus, even though some of the inactivated preparations had ...
| Abstract | Normal mouse bone marrow cells were exposed to encephalomyocarditis virus (EMC), reovirus type 3 (REO3), influenza virus (FLU), and Newcastle disease virus (NDV) then assayed for granulocyte-macrophage precursor cells by the technique of colony formation in agar. Exposure to EMC, REO3, and FLU caused a slight but variable loss of colony-forming potential, whereas exposure to NDV caused a very marked loss. NDV acted directly on the cells, not indirectly through release of colony-inhibiting factors or destruction of colony-stimulating factor. Experiments with NDV inactivated by heat, ether, or ultraviolet irradiation indicated that colony inhibition was associated with fully infective virus, even though some of the inactivated preparations had retained full hemagglutinin, neuraminidase, or hemolytic activity. |
|---|---|
| MeSH term(s) | Animals ; Bone Marrow/growth & development ; Bone Marrow Cells ; Cells, Cultured ; Cytopathogenic Effect, Viral ; Encephalomyocarditis virus/immunology ; Female ; Hemagglutination Tests ; Hemolysin Proteins/analysis ; L Cells ; Mice ; Neuraminidase/isolation & purification ; Newcastle disease virus/enzymology ; Newcastle disease virus/immunology ; Orthomyxoviridae/immunology ; Ovum ; Reoviridae/immunology ; Viral Plaque Assay ; Virus Cultivation |
| Chemical Substances | Hemolysin Proteins ; Neuraminidase (EC 3.2.1.18) |
| Language | English |
| Publishing date | 1975-03 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 218698-6 |
| ISSN | 1098-5522 ; 0019-9567 |
| ISSN (online) | 1098-5522 |
| ISSN | 0019-9567 |
| DOI | 10.1128/iai.11.3.424-428.1975 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
| Zs.A 684: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.