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  1. Article ; Online: COVID-19 Gastrointestinal Symptoms and Attenuation of the Immune Response to SARS-CoV-2.

    Miller, Jonathan / Yan, Kelley S

    Gastroenterology

    2021  Volume 160, Issue 7, Page(s) 2251–2254

    MeSH term(s) COVID-19 ; Gastrointestinal Diseases ; Humans ; Immunity ; SARS-CoV-2
    Language English
    Publishing date 2021-03-19
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2021.03.029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: An alternative to airborne droplet transmission route of SARS-CoV-2, the feco-oral route, as a factor shaping COVID-19 pandemic.

    Targoński, Ryszard / Gąsecka, Aleksandra / Prowancki, Adrian / Targoński, Radosław

    Medical hypotheses

    2022  Volume 166, Page(s) 110903

    Abstract: ... with gastrointestinal symptoms, less inflammatory response, and better prognosis. The presence of SARS-CoV-2 was ... population immunity, possibly through increased SARS-CoV-2 antigen exposure in the gastrointestinal tract ... The Chinese scenario, a rapid increase in the frequency of SARS-CoV-2 infections and sudden decline ...

    Abstract The Chinese scenario, a rapid increase in the frequency of SARS-CoV-2 infections and sudden decline, is uncommon worldwide. Enormous differences in COVID-19 severity among individual countries are the striking findings of the pandemics. It has been demonstrated that a mild course of COVID-19 is associated with gastrointestinal symptoms, less inflammatory response, and better prognosis. The presence of SARS-CoV-2 was observed longer in the gastrointestinal tract than in respiratory swabs, promoting feco-oral transmissions and mild virus attenuation. The spread of the pandemic and its severity might, consequently, depends on the dominant environmental route of infection and emerging immunity. We hypothesize that the feco-oral SARS-CoV-2 transmission may help to achieve the long-term immunity against COVID-19, since it enables the continuous contact with viral antigens in the gastrointestinal tract, resulting in lower mortality rate. To conclude, countries producing rice through traditional methods developed rapidly emerging long-lasting population immunity, possibly through increased SARS-CoV-2 antigen exposure in the gastrointestinal tract. Our hypothesis brings attention to this potential route of herd immunity against SARS-CoV-2 which warrants further investigation in the future.
    Language English
    Publishing date 2022-07-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2022.110903
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1132: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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