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Article ; Online: Importance of hyperglycemia in COVID-19 intensive-care patients: Mechanism and treatment strategy.

Mirzaei, Fatemeh / Khodadadi, Iraj / Vafaei, Seyyed Alireza / Abbasi-Oshaghi, Ebrahim / Tayebinia, Heidar / Farahani, Farhad

Primary care diabetes

2021  Volume 15, Issue 3, Page(s) 409–416

Abstract: ... COVID-19 patients and recommend treatment strategy to reduce mortality rate and prevent adverse outcomes ... This review reported that coronavirus disease 2019 (COVID-19) infected patients with short time ... bed rest or quarantine and airway inflammation are at more risk of developing hyperglycemia and ...

Abstract This review reported that coronavirus disease 2019 (COVID-19) infected patients with short time bed rest or quarantine and airway inflammation are at more risk of developing hyperglycemia and insulin resistance. This condition can induce oxidative stress, decrease immune system function, impair endothelial function, induce apoptosis, and reduce antioxidant in the lungs. We provide a possible mechanism in severe COVID-19 patients and recommend treatment strategy to reduce mortality rate and prevent adverse outcomes after intensive care unit (ICU).
MeSH term(s) Biomarkers/blood ; Blood Glucose/metabolism ; COVID-19/complications ; COVID-19/epidemiology ; Disease Management ; Global Health ; Hospitalization/trends ; Humans ; Hyperglycemia/epidemiology ; Hyperglycemia/etiology ; Hyperglycemia/therapy ; Incidence ; Intensive Care Units ; Pandemics ; SARS-CoV-2 ; Survival Rate/trends
Chemical Substances Biomarkers ; Blood Glucose
Language English
Publishing date 2021-01-09
Publishing country England
Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID 2273997-X
ISSN 1878-0210 ; 1751-9918
ISSN (online) 1878-0210
ISSN 1751-9918
DOI 10.1016/j.pcd.2021.01.002
Database MEDical Literature Analysis and Retrieval System OnLINE

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