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  1. Article: Psychosocial treatment and interventions for bipolar disorder: a systematic review.

    Miziou, Stella / Tsitsipa, Eirini / Moysidou, Stefania / Karavelas, Vangelis / Dimelis, Dimos / Polyzoidou, Vagia / Fountoulakis, Konstantinos N

    Annals of general psychiatry

    2015  Volume 14, Page(s) 19

    Abstract: ... pharmacotherapy. This indicates the need for effective and affordable adjunctive psychosocial interventions ... Background: Bipolar disorder (BD) is a chronic disorder with a high relapse rate, significant ... of key words. The review followed the recommendations of the Preferred Items for Reporting of Systematic ...

    Abstract Background: Bipolar disorder (BD) is a chronic disorder with a high relapse rate, significant general disability and burden and with a psychosocial impairment that often persists despite pharmacotherapy. This indicates the need for effective and affordable adjunctive psychosocial interventions, tailored to the individual patient. Several psychotherapeutic techniques have tried to fill this gap, but which intervention is suitable for each patient remains unknown and it depends on the phase of the illness.
    Methods: The papers were located with searches in PubMed/MEDLINE through May 1st 2015 with a combination of key words. The review followed the recommendations of the Preferred Items for Reporting of Systematic Reviews and Meta-Analyses statement.
    Results: The search returned 7,332 papers; after the deletion of duplicates, 6,124 remained and eventually 78 were included for the analysis. The literature supports the usefulness only of psychoeducation for the relapse prevention of mood episodes and only in a selected subgroup of patients at an early stage of the disease who have very good, if not complete remission, of the acute episode. Cognitive-behavioural therapy and interpersonal and social rhythms therapy could have some beneficial effect during the acute phase, but more data are needed. Mindfulness interventions could only decrease anxiety, while interventions to improve neurocognition seem to be rather ineffective. Family intervention seems to have benefits mainly for caregivers, but it is uncertain whether they have an effect on patient outcomes.
    Conclusion: The current review suggests that the literature supports the usefulness only of specific psychosocial interventions targeting specific aspects of BD in selected subgroups of patients.
    Language English
    Publishing date 2015-07-07
    Publishing country England
    Document type Journal Article
    ISSN 1744-859X
    ISSN 1744-859X
    DOI 10.1186/s12991-015-0057-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Psychosocial interventions for bipolar disorder: a review of literature and introduction of the systematic treatment enhancement program.

    Miklowitz, David J / Otto, Michael W

    Psychopharmacology bulletin

    2008  Volume 40, Issue 4, Page(s) 116–131

    Abstract: ... Program for Bipolar Disorder (STEP - BD). The objectives, design, and potential contributions of the STEP ... in forestalling episodes of bipolar disorder (BPD)? This article give s the rationale for including psychosocial ... with a psychosocial control condition in the context of the ongoing, multi-center Systematic Treatment Enhancement ...

    Abstract What is the evidence that psychosocial treatment adds to the efficacy of pharmacotherapy in forestalling episodes of bipolar disorder (BPD)? This article give s the rationale for including psychosocial intervention in the outpatient maintenance of BPD. Attention is placed on the three psychosocial modalities that have achieved empirical support in randomized trials: family psychoeducational treatment, cognitive-behavioral therapy, and interpersonal and social rhythm therapy. These three treatments are being contrasted with a psychosocial control condition in the context of the ongoing, multi-center Systematic Treatment Enhancement Program for Bipolar Disorder (STEP - BD). The objectives, design, and potential contributions of the STEP-BD study are explained. Future directions for the evaluation and dissemination of manual-based psychosocial interventions are discussed.
    MeSH term(s) Bipolar Disorder/psychology ; Bipolar Disorder/therapy ; Cognitive Behavioral Therapy ; Humans ; Psychotherapy/methods ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2008-01-25
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 4113-0
    ISSN 0048-5764 ; 0376-0162
    ISSN 0048-5764 ; 0376-0162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Systematic Review of Psychosocial Smoking Cessation Interventions for People with Serious Mental Illness.

    Hawes, Mark R / Roth, Kimberly B / Cabassa, Leopoldo J

    Journal of dual diagnosis

    2021  Volume 17, Issue 3, Page(s) 216–235

    Abstract: ... illness (SMI; e.g., schizophrenia, bipolar disorder). This systematic literature review described ... randomized control trials of psychosocial smoking cessation interventions for people with SMI, rated their methodological ... rigor, evaluated the inclusion of racial/ethnic and sexual/gender minorities, and examined ...

    Abstract Objective: Tobacco smoking is a major driver of premature mortality in people with serious mental illness (SMI; e.g., schizophrenia, bipolar disorder). This systematic literature review described randomized control trials of psychosocial smoking cessation interventions for people with SMI, rated their methodological rigor, evaluated the inclusion of racial/ethnic and sexual/gender minorities, and examined smoking cessation outcomes.
    MeSH term(s) Behavior Therapy ; Bupropion/therapeutic use ; Humans ; Mental Disorders ; Smoking ; Smoking Cessation
    Chemical Substances Bupropion (01ZG3TPX31)
    Language English
    Publishing date 2021-07-19
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Research Support, N.I.H., Extramural ; Systematic Review
    ZDB-ID 2179549-6
    ISSN 1550-4271 ; 1550-4263
    ISSN (online) 1550-4271
    ISSN 1550-4263
    DOI 10.1080/15504263.2021.1944712
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pharmacological and Psychosocial Treatment of Adults With Gambling Disorder: A Meta-Review.

    Di Nicola, Marco / De Crescenzo, Franco / D'Alò, Gian Loreto / Remondi, Chiara / Panaccione, Isabella / Moccia, Lorenzo / Molinaro, Marzia / Dattoli, Luigi / Lauriola, Alessandro / Martinelli, Silvia / Giuseppin, Giulia / Maisto, Francesco / Crosta, Maria Luigia / Di Pietro, Salvatore / Amato, Laura / Janiri, Luigi

    Journal of addiction medicine

    2019  Volume 14, Issue 4, Page(s) e15–e23

    Abstract: ... review the literature on the pharmacological and psychosocial treatment of adults with GD, and to identify possible ... bipolar disorders. Cognitive behavioral therapy (CBT) was the most commonly used psychological intervention and ... and combined treatment of adults with GD. Twenty-six studies were eventually included in this meta ...

    Abstract Background and objectives: Gambling disorder (GD) leads to impaired socioeconomical functioning and increased social costs. Although the research on GD has been rising over the years, approved treatment guidelines are currently not available. The aim of this study was to systematically review the literature on the pharmacological and psychosocial treatment of adults with GD, and to identify possible agreed-upon standards of care.
    Methods: MEDLINE, PubMed, Cochrane, Web of Science, Embase, and CINAHL electronic databases were searched up to April 2019 for systematic reviews on pharmacological, psychosocial, and combined treatment of adults with GD. Twenty-six studies were eventually included in this meta-review.
    Results: Studies reported promising results of opioid antagonists and mood stabilizers in reducing GD-related symptomatology. Lithium was particularly effective in subjects with comorbid bipolar disorders. Cognitive behavioral therapy (CBT) was the most commonly used psychological intervention and reduced global severity, gambling frequency, and financial loss. Motivational interviewing (MI) seemed to improve several GD domains, alone or in combination with CBT. Self-help interventions (SHIs) showed some efficacy in promoting treatment-seeking, and in combination with other treatments.
    Conclusions: We found moderate evidence of effect for CBT, but weaker evidence for pharmacotherapy and SHIs. Results suggested some efficacy for MI in the short but not in the long term. It is likely that certain interventions might be more effective than others on specific features of GD. Further studies are needed to compare the efficacy and acceptability of individual and combined psychosocial and pharmacological interventions, to deliver patient-tailored treatments.
    MeSH term(s) Adult ; Bipolar Disorder ; Cognitive Behavioral Therapy ; Gambling/therapy ; Humans ; Motivational Interviewing ; Systematic Reviews as Topic
    Language English
    Publishing date 2019-11-13
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Review
    ISSN 1935-3227
    ISSN (online) 1935-3227
    DOI 10.1097/ADM.0000000000000574
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Psychosocial interventions in bipolar disorder: a review.

    Lolich, María / Vázquez, Gustavo H / Alvarez, Lina M / Tamayo, Jorge M

    Actas espanolas de psiquiatria

    2012  Volume 40, Issue 2, Page(s) 84–92

    Abstract: ... several validated psychosocial interventions for treating bipolar disorder, their efficacy needs to be specified ... Introduction: Multiple psychosocial interventions for bipolar disorder have been proposed ... behavioral, psychoeducational, systematic care models, interpersonal and family therapy interventions were ...

    Abstract Introduction: Multiple psychosocial interventions for bipolar disorder have been proposed in recent years. Therefore, we consider that a critical review of empirically validated models would be useful.
    Methods: A review of the literature was conducted in Medline/PubMed for articles published during 2000-2010 that respond to the combination of "bipolar disorder" with the following key words: "psychosocial intervention", "psychoeducational intervention" and "psychotherapy".
    Results: Cognitive-behavioral, psychoeducational, systematic care models, interpersonal and family therapy interventions were found to be empirically validated. All of them reported significant improvements in therapeutic adherence and in the patients' functionality.
    Conclusions: Although there are currently several validated psychosocial interventions for treating bipolar disorder, their efficacy needs to be specified in relation to more precise variables such as clinical type, comorbid disorders, stages or duration of the disease. Taking into account these clinical features would enable a proper selection of the most adequate intervention according to the patient's specific characteristics.
    MeSH term(s) Bipolar Disorder/therapy ; Cognitive Therapy ; Humans ; Psychotherapy/methods
    Language English
    Publishing date 2012-03
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 1480971-0
    ISSN 1578-2735 ; 1575-071X ; 1139-9287
    ISSN (online) 1578-2735
    ISSN 1575-071X ; 1139-9287
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Psychosocial interventions in the treatment of youth diagnosed or at high-risk for pediatric bipolar disorder: A review of the literature.

    Frías, Álvaro / Palma, Cárol / Farriols, Núria

    Revista de psiquiatria y salud mental

    2015  Volume 8, Issue 3, Page(s) 146–156

    Abstract: Pediatric bipolar disorder (PBD) has emerged as a research field in which psychosocial treatments ... through a systematic review aimed of establishing their effectiveness and feasibility as adjunctive therapies for youth ... on case reports. Studies of psychosocial treatments provide concluding results concerning their feasibility and ...

    Abstract Pediatric bipolar disorder (PBD) has emerged as a research field in which psychosocial treatments have provided a plethora of empirical findings over the last decade. We addressed this issue through a systematic review aimed of establishing their effectiveness and feasibility as adjunctive therapies for youth with PBD or at high-risk for PBD. A comprehensive search of databases was performed between 1990 and September 2014. Overall, 33 studies were specifically related to the issue and 20 of them were original articles. Evidence suggests that both "multi-family psychoeducational psychotherapy' and "family-focused therapy" are possible effective treatments for PBD. Likewise, "child and family-focused cognitive-behavioral therapy" may be characterized as a treatment in its experimental phase. The remaining therapies fail to obtain enough empirical support due to inconsistent findings among clinical trials or data solely based on case reports. Studies of psychosocial treatments provide concluding results concerning their feasibility and acceptability. Larger sample sizes and more randomized controlled trials are mandatory for diminishing methodological shortcomings encountered in the treatments displayed.
    MeSH term(s) Adolescent ; Bipolar Disorder/therapy ; Child ; Cognitive Therapy ; Humans ; Psychotherapy/methods ; Treatment Outcome
    Language Spanish
    Publishing date 2015-07
    Publishing country Spain
    Document type Journal Article ; Review
    ISSN 1989-4600
    ISSN (online) 1989-4600
    DOI 10.1016/j.rpsm.2014.11.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Psychological and psychosocial interventions for cannabis cessation in adults: a systematic review short report.

    Cooper, Katy / Chatters, Robin / Kaltenthaler, Eva / Wong, Ruth

    Health technology assessment (Winchester, England)

    2015  Volume 19, Issue 56, Page(s) 1–130

    Abstract: ... To systematically review the clinical effectiveness of psychological and psychosocial interventions for cannabis ... associated with an increased risk of medical and psychological problems. This systematic review evaluates ... dependence, motivation to change and intervention adherence.: Results: The review included 33 RCTs ...

    Abstract Background: Cannabis is the most commonly used illicit drug worldwide. Cannabis dependence is a recognised psychiatric diagnosis, often diagnosed via the Diagnostic and Statistical Manual of Mental Disorders criteria and the International Classification of Diseases, 10th Revision. Cannabis use is associated with an increased risk of medical and psychological problems. This systematic review evaluates the use of a wide variety of psychological and psychosocial interventions, such as motivational interviewing (MI), cognitive-behavioural therapy (CBT) and contingency management.
    Objective: To systematically review the clinical effectiveness of psychological and psychosocial interventions for cannabis cessation in adults who use cannabis regularly.
    Data sources: Studies were identified via searches of 11 databases [MEDLINE, EMBASE, Cochrane Controlled Trials Register, Health Technology Assessment (HTA) database, Database of Abstracts of Reviews of Effects, Cochrane Database of Systematic Reviews, NHS Economic Evaluation Database, PsycINFO, Web of Science Conference Proceedings Citation Index, ClinicalTrials.gov and metaRegister of Current Controlled Trials] from inception to February 2014, searching of existing reviews and reference tracking.
    Methods: Randomised controlled trials (RCTs) assessing psychological or psychosocial interventions in a community setting were eligible. Risk of bias was assessed using adapted Cochrane criteria and narrative synthesis was undertaken. Outcomes included change in cannabis use, severity of cannabis dependence, motivation to change and intervention adherence.
    Results: The review included 33 RCTs conducted in various countries (mostly the USA and Australia). General population studies: 26 studies assessed the general population of cannabis users. Across six studies, CBT (4-14 sessions) significantly improved outcomes (cannabis use, severity of dependence, cannabis problems) compared with wait list post treatment, maintained at 9 months in the one study with later follow-up. Studies of briefer MI or motivational enhancement therapy (MET) (one or two sessions) gave mixed results, with some improvements over wait list, while some comparisons were not significant. Four studies comparing CBT (6-14 sessions) with MI/MET (1-4 sessions) also gave mixed results: longer courses of CBT provided some improvements over MI. In one small study, supportive-expressive dynamic psychotherapy (16 sessions) gave significant improvements over one-session MI. Courses of other types of therapy (social support group, case management) gave similar improvements to CBT based on limited data. Limited data indicated that telephone- or internet-based interventions might be effective. Contingency management (vouchers for abstinence) gave promising results in the short term; however, at later follow-ups, vouchers in combination with CBT gave better results than vouchers or CBT alone. Psychiatric population studies: seven studies assessed psychiatric populations (schizophrenia, psychosis, bipolar disorder or major depression). CBT appeared to have little effect over treatment as usual (TAU) based on four small studies with design limitations (both groups received TAU and patients were referred). Other studies reported no significant difference between types of 10-session therapy.
    Limitations: Included studies were heterogeneous, covering a wide range of interventions, comparators, populations and outcomes. The majority were considered at high risk of bias. Effect sizes were reported in different formats across studies and outcomes.
    Conclusions: Based on the available evidence, courses of CBT and (to a lesser extent) one or two sessions of MI improved outcomes in a self-selected population of cannabis users. There was some evidence that contingency management enhanced long-term outcomes in combination with CBT. Results of CBT for cannabis cessation in psychiatric populations were less promising, but may have been affected by provision of TAU in both groups and the referred populations. Future research should focus on the number of CBT/MI sessions required and potential clinical effectiveness and cost-effectiveness of shorter interventions. CBT plus contingency management and mutual aid therapies warrant further study. Studies should consider potential effects of recruitment methods and include inactive control groups and long-term follow-up. TAU arms in psychiatric population studies should aim not to confound the study intervention.
    Study registration: This study is registered as PROSPERO CRD42014008952.
    Funding: The National Institute for Health Research HTA programme.
    MeSH term(s) Cognitive Therapy/methods ; Group Processes ; Humans ; Marijuana Abuse/therapy ; Mental Disorders/therapy ; Motivational Interviewing/methods ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2015-07
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 2006765-3
    ISSN 2046-4924 ; 1366-5278
    ISSN (online) 2046-4924
    ISSN 1366-5278
    DOI 10.3310/hta19560
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Psychosocial interventions for the prevention of relapse in bipolar disorder: systematic review of controlled trials.

    Beynon, Suzanne / Soares-Weiser, Karla / Woolacott, Nerys / Duffy, Steven / Geddes, John R

    The British journal of psychiatry : the journal of mental science

    2008  Volume 192, Issue 1, Page(s) 5–11

    Abstract: ... for the prevention of relapse in bipolar disorder.: Method: A systematic review and meta-analysis of randomised or ... for some individuals with bipolar disorder.: Aims: To determine the effectiveness of psychosocial interventions ... Cognitive-behavioural therapy, group psychoeducation and possibly family therapy may be beneficial as adjuncts ...

    Abstract Background: Pharmacological interventions alone do not provide sufficient benefit for some individuals with bipolar disorder.
    Aims: To determine the effectiveness of psychosocial interventions for the prevention of relapse in bipolar disorder.
    Method: A systematic review and meta-analysis of randomised or quasi-randomised controlled trials were conducted.
    Results: Cognitive-behavioural therapy or group psychoeducation may be effective for relapse prevention in stable individuals. Family therapy was no more or less effective than individual psychosocial therapy or crisis management. There is no evidence that care management or integrated group therapy is effective in the prevention of relapse.
    Conclusions: Cognitive-behavioural therapy, group psychoeducation and possibly family therapy may be beneficial as adjuncts to pharmacological maintenance treatments.
    MeSH term(s) Bipolar Disorder/drug therapy ; Bipolar Disorder/prevention & control ; Combined Modality Therapy ; Databases, Bibliographic ; Humans ; Outcome and Process Assessment (Health Care) ; Psychotherapy/methods ; Randomized Controlled Trials as Topic ; Secondary Prevention ; Statistics as Topic
    Language English
    Publishing date 2008-01
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 218103-4
    ISSN 1472-1465 ; 0007-1250
    ISSN (online) 1472-1465
    ISSN 0007-1250
    DOI 10.1192/bjp.bp.107.037887
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: How well do psychosocial interventions work in bipolar disorder?

    Zaretsky, Ari E / Rizvi, Sakina / Parikh, Sagar V

    Canadian journal of psychiatry. Revue canadienne de psychiatrie

    2007  Volume 52, Issue 1, Page(s) 14–21

    Abstract: Objective: Although medication is the mainstay of treatment for bipolar disorder ... Although psychological models of bipolar disorder fail to inform the psychotherapy treatment to the same extent ... of the recent literature pertaining to psychosocial interventions in bipolar, using MEDLINE and PsycINFO ...

    Abstract Objective: Although medication is the mainstay of treatment for bipolar disorder, several adjunctive psychosocial interventions have been manualized over the last decade. This paper's objective is to empirically evaluate the different treatment approaches.
    Method: We conducted a systematic review of the recent literature pertaining to psychosocial interventions in bipolar, using MEDLINE and PsycINFO. Bibliographies of papers were scrutinized for further relevant references. Articles published from 1999 up to and including 2006 were reviewed. Randomized controlled trials were emphasized.
    Conclusions: Although psychological models of bipolar disorder fail to inform the psychotherapy treatment to the same extent as in unipolar depression, manualized adjunctive, short-term psychotherapies have been shown to offer fairly consistent benefits to bipolar disorder patients. Cognitive-behavioural therapy, family-focused therapy, and psychoeducation offer the most robust efficacy in regard to relapse prevention, while interpersonal therapy and cognitive-behavioural therapy may offer more benefit in treating residual depressive symptoms.
    MeSH term(s) Bipolar Disorder/therapy ; Humans ; Patient Satisfaction ; Psychology ; Psychotherapy/methods ; Treatment Outcome
    Language English
    Publishing date 2007-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 304227-3
    ISSN 1497-0015 ; 0706-7437 ; 0008-4824
    ISSN (online) 1497-0015
    ISSN 0706-7437 ; 0008-4824
    DOI 10.1177/070674370705200104
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Pharmacological and psychosocial management of mental, neurological and substance use disorders in low- and middle-income countries: issues and current strategies.

    de Jesus Mari, Jair / Tófoli, Luís Fernando / Noto, Cristiano / Li, Li M / Diehl, Alessandra / Claudino, Angélica M / Juruena, Mario F

    Drugs

    2013  Volume 73, Issue 14, Page(s) 1549–1568

    Abstract: ... by the World Health Organization (WHO) (anxiety, stress-related and bodily distress disorders; depression and bipolar disorder ... of psychosocial interventions, can represent a cost-effective way to expand treatment of most MNS. The translation ... to the affordable essential psychotropics and psychosocial interventions which are proven to be cost effective ...

    Abstract Mental, neurological, and substance use disorders (MNS) are among the largest sources of medical disability in the world, surpassing both cardiovascular disease and cancer. The picture is not different in low- and middle-income countries (LAMIC) where the relative morbidity associated with MNS is increasing, as a consequence of improvement in general health indicators and longevity. However, 80 % of individuals with MNS live in LAMIC but only close to 20 % of cases receive some sort of treatment. The main aim of this article is to provide non-specialist health workers in LAMIC with an accessible guide to the affordable essential psychotropics and psychosocial interventions which are proven to be cost effective for treating the main MNS. The MNS discussed in this article were selected on the basis of burden, following the key priority conditions selected by the Mental Health Action Programme (mhGAP) developed by the World Health Organization (WHO) (anxiety, stress-related and bodily distress disorders; depression and bipolar disorder; schizophrenia; alcohol and drug addiction; and epilepsy), with the addition of eating disorders, because of their emergent trend in middle-income countries. We review best evidence-based clinical practice in these areas, with a focus on drugs from the WHO Model List of Essential Medicines and the psychosocial interventions available in LAMIC for the management of these conditions in primary care. We do this by reviewing guidelines developed by prestigious professional associations and government agencies, clinical trials conducted in LAMIC and systematic reviews (including Cochrane reviews) identified from the main international literature databases (MEDLINE, EMBASE and PsycINFO). In summary, it can be concluded that the availability and use of the psychotropics on the WHO Model List of Essential Medicines in LAMIC, plus an array of psychosocial interventions, can represent a cost-effective way to expand treatment of most MNS. The translation of these findings into policies can be achieved by relatively low supplementary funding, and limited effort engendered by governments and policy makers in LAMIC.
    MeSH term(s) Cost-Benefit Analysis/economics ; Developing Countries/economics ; Humans ; Mental Disorders/drug therapy ; Mental Disorders/economics ; Mental Disorders/psychology ; Nervous System Diseases/drug therapy ; Nervous System Diseases/economics ; Nervous System Diseases/psychology ; Poverty/economics ; Substance-Related Disorders/drug therapy ; Substance-Related Disorders/economics ; Substance-Related Disorders/psychology
    Language English
    Publishing date 2013-09-03
    Publishing country New Zealand
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 120316-2
    ISSN 1179-1950 ; 0012-6667
    ISSN (online) 1179-1950
    ISSN 0012-6667
    DOI 10.1007/s40265-013-0113-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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