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Article: Clinical characteristics, gastrointestinal manifestations and outcomes of COVID-19 patients in Iran; does the location matters?

Mokarram, Pooneh / Dalivand, Maryam Mehdipour / Pizuorno, Antonio / Aligolighasemabadi, Farnaz / Sadeghdoust, Mohammadamin / Sadeghdoust, Ebtesam / Aduli, Farshad / Oskrochi, Gholamreza / Brim, Hassan / Ashktorab, Hassan

World journal of clinical cases

2021  Volume 9, Issue 18, Page(s) 4654–4667

Abstract: ... comorbidities, but their distribution was different in COVID-19 patients in the four studied regions of Iran ... Background: Coronavirus disease 2019 (COVID-19) started in Asia, and Iran was one of its first ... of COVID-19 patients was 51.1 years, and 56% were male. Mortality rate was 17%. Cough with 84.6%, shortness ...

Abstract Background: Coronavirus disease 2019 (COVID-19) started in Asia, and Iran was one of its first epicenters.
Aim: To study the gastrointestinal (GI) symptoms and comorbidities associated with this pandemic in four different regions of Iran.
Methods: We analyzed data from severe acute respiratory syndrome coronavirus 2 positive patients evaluated at four hospitals of Iran (
Results: The average age of COVID-19 patients was 51.1 years, and 56% were male. Mortality rate was 17%. Cough with 84.6%, shortness of breath with 71.4%, fever with 52.7%, and loss of appetite with 43.9% were the main symptoms. Overall cardiac disease was the most common comorbidity with an average of 28.5% followed by hypertension (28.5%) and diabetes (25.2%). The highest comorbidity in North (Rasht) was diabetes (30%) and in South (Dezful) hypertension (37%). Shiraz leads cardiac disease with 43.4%. The most reported GI symptoms included nausea, diarrhea, vomiting, and abdominal pain, with 42.8%, 31.8%, 26.8%, and 12% prevalence, respectively. In addition, albumin, alkaline phosphatase, aspartate aminotransferase, and alanine aminotransferase were elevated in 26.3%.
Conclusion: Our results show hypertension and diabetes as the most common comorbidities, but their distribution was different in COVID-19 patients in the four studied regions of Iran. Nausea, diarrhea, and elevated liver enzymes were the most common GI symptoms. There was also a high mortality rate that was associated with high infection rates in Iran at the beginning of the pandemic.
Language English
Publishing date 2021-07-03
Publishing country United States
Document type Journal Article
ISSN 2307-8960
ISSN 2307-8960
DOI 10.12998/wjcc.v9.i18.4654
Database MEDical Literature Analysis and Retrieval System OnLINE

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