Article ; Online: Colorectal surgery obesity-related morbidity during COVID-19.
2020 Volume 16, Issue 9, Page(s) 1372–1375
Abstract: ... to present a case of acute large bowel perforation in a morbidly obese patient with coronavirus disease 2019 ...
| Abstract | Tocilizumab, a monoclonal antiinterluekin-6 receptor antibody, has been empirically used in the treatment of cytokine release syndrome associated with severe coronavirus disease 2019 infections. The efficacy and safety of these medications for these patients is unknown. The purpose of this report was to present a case of acute large bowel perforation in a morbidly obese patient with coronavirus disease 2019 pneumonia who received empiric Tocilizumab. This case report analyzes the risks of acute large bowel perforation after using this medication empirically and discusses the appropriate management of this adverse event. |
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| MeSH term(s) | Antibodies, Monoclonal, Humanized/adverse effects ; Betacoronavirus ; COVID-19 ; Cecal Diseases/diagnosis ; Cecal Diseases/etiology ; Cecal Diseases/surgery ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/drug therapy ; Cytokine Release Syndrome/etiology ; Cytokine Release Syndrome/prevention & control ; Female ; Humans ; Intestinal Perforation/diagnosis ; Intestinal Perforation/etiology ; Intestinal Perforation/surgery ; Middle Aged ; Obesity, Morbid/complications ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/drug therapy ; SARS-CoV-2 ; COVID-19 Drug Treatment |
| Chemical Substances | Antibodies, Monoclonal, Humanized ; tocilizumab (I031V2H011) |
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-07-09 |
| Publishing country | United States |
| Document type | Case Reports ; Journal Article ; Video-Audio Media |
| ZDB-ID | 2274243-8 |
| ISSN | 1878-7533 ; 1550-7289 |
| ISSN (online) | 1878-7533 |
| ISSN | 1550-7289 |
| DOI | 10.1016/j.soard.2020.06.011 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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