LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 5 of total 5

Search options

  1. Article: Glans Penis Augmentation Using Hyaluronic Acid Gel as an Injectable Filler.

    Moon, Du Geon / Kwak, Tae Il / Kim, Je Jong

    The world journal of men's health

    2015  Volume 33, Issue 2, Page(s) 50–61

    Abstract: ... using injectable hyaluronic acid (HA) gel is a novel and useful therapy and an effective and safe ... protocol for immediate side effects. Currently, GPA using injectable HA gel is not recommended ... Glans penis augmentation (GPA) has received little attention from experts despite the existence ...

    Abstract Glans penis augmentation (GPA) has received little attention from experts despite the existence of a subset of patients who may be dissatisfied with a small glans or poor tumescence of the glans during erection. Recently, GPA using an injectable filler or implantation of a graft or filler has been developed. Despite a demanding injection technique and inevitable uneven undulation of the glandular surface, GPA using injectable hyaluronic acid (HA) gel is a novel and useful therapy and an effective and safe procedure for soft tissue enhancement. For long-term presence of implants, timed supplementation can be used similar to that for fascial plasty. In complications such as mucosal necrosis of the glans penis, most cases occur from the use of non-HA gel or an unpurified form and misunderstanding of the management protocol for immediate side effects. Currently, GPA using injectable HA gel is not recommended in the International Society for Sexual Medicine guideline due to possible sensory loss. In a 5-year long-term follow-up of GPA by subcutaneous injection of HA gel, the residual volume of implants decreased by 15% of the maximal glandular circumference, but was still effective for alleviating the hypersensitivity of the glans penis in premature ejaculation patients. For efficacy in premature ejaculation, selection of appropriate candidates is the most important factor for success. GPA does not harm erectile function and is less invasive and irreversible compared to dorsal neurectomy. To refine the procedure, more interest and well-designed studies are required for the establishment of the procedure.
    Language English
    Publishing date 2015-08-19
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 2719786-4
    ISSN 2287-4690 ; 2287-4208
    ISSN (online) 2287-4690
    ISSN 2287-4208
    DOI 10.5534/wjmh.2015.33.2.50
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Complications of glans penis augmentation.

    Ahn, Sun Tae / Il Kwak, Tae / Park, Kwang Sung / Kim, Je Jong / Moon, Du Geon

    International journal of impotence research

    2018  Volume 31, Issue 4, Page(s) 245–255

    Abstract: ... hyaluronic acid (HA) gel has been used for GPA. The attractiveness of HA gel fillers and interest ... longevity of the gel and glans surface undulation, which are the primary limitations of GPA using HA gel ... Despite the controversy regarding penile augmentation (PA), glans penis augmentation (GPA) is used ...

    Abstract Despite the controversy regarding penile augmentation (PA), glans penis augmentation (GPA) is used in penile reconstructive surgery in selected patients with small glans penis. Since 2003, injectable hyaluronic acid (HA) gel has been used for GPA. The attractiveness of HA gel fillers and interest in this technique have led to the use of other fillers for GPA, particularly irreversible fillers that improve the longevity of HA gels. Conversely, indirect glans augmentation via implantation of dermofat grafts or scaffolds between the corpus spongiosum and the distal tip of the corpus cavernosum is used to overcome poor longevity of the gel and glans surface undulation, which are the primary limitations of GPA using HA gel. Unfortunately, these implants form hard painful lumps over time in most patients and are difficult to remove. Blunt dissection is an invasive procedure that may cause vascular compromise and consequent glans necrosis in a few patients. We present our review regarding the current status of GPA for a more comprehensive understanding of this subject. Additionally, we have discussed a few complicated cases that were referred to us.
    MeSH term(s) Humans ; Male ; Patient Satisfaction ; Penis/surgery ; Urologic Surgical Procedures, Male/adverse effects ; Urologic Surgical Procedures, Male/methods
    Language English
    Publishing date 2018-11-26
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1034295-3
    ISSN 1476-5489 ; 0955-9930
    ISSN (online) 1476-5489
    ISSN 0955-9930
    DOI 10.1038/s41443-018-0097-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2910: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Practice Patterns Among Korean Urologists for Glans Penis Augmentation Using Hyaluronic Acid Filler in the Management of Premature Ejaculation.

    Jeong, Hyeong Guk / Ahn, Sun Tae / Kim, Jong Wook / Seo, Kyung Keun / Lee, Dong Soo / Uh, Hong Sun / Kim, Je Jong / Moon, Du Geon

    Sexual medicine

    2018  Volume 6, Issue 4, Page(s) 297–301

    Abstract: Introduction: Glans penis augmentation (GPA) using hyaluronic acid (HA) gel has been developed ... Using Hyaluronic Acid Filler in the Management of Premature Ejaculation. Sex Med 2018;6:297-301. ... Jeong HG, Ahn ST, Kim JW, et al. Practice Patterns Among Korean Urologists for Glans Penis Augmentation ...

    Abstract Introduction: Glans penis augmentation (GPA) using hyaluronic acid (HA) gel has been developed for treating premature ejaculation (PE) with penile hypersensitivity. The injected HA filler creates a barrier that reduces the tactile stimuli to the hypersensitive dorsal nerve. Although the HA filler is biodegradable and is believed to not cause permanent loss of sexual function, the current International Society for Sexual Medicine guideline for PE does not recommend this procedure owing to concerns regarding sexual dysfunction.
    Aim: To investigate the practice patterns for GPA using HA filler among Korean urologists, and to identify whether urologist experienced patient reports of sexual dysfunction post-treatment.
    Methods: Between March 2016 and July 2016, a specially designed questionnaire was mailed to 86 selected Korean urologists who had used injectable materials to treat PE.
    Main outcome measures: The prevalence and awareness of sexual dysfunction after GPA using HA filler were evaluated.
    Results: Overall, 56 urologists completed the survey (response rate: 69.2%), of which 36 (64.3%) had performed GPA using HA filler. They reported having performed a combined total of 4,344 such GPA procedures. Most urologists (72.7%) performed GPA using HA filler in patients who benefit from topical anesthetics. Patients with a history of failed pharmacotherapy (59.1%) and selective dorsal nerve neurotomy (45.5%) were selected for GPA using HA filler. The respondents (44.4%) encountered overall 206 (4.7%) cases of patients reports of recurrence of PE. Interestingly, only 36 (0.8%) cases of glans pain or paresthesia and no cases of erectile dysfunction post-treatment were reported.
    Conclusion: Korean urologists performed GPA using HA filler when pharmacotherapy failed or if there was a response to topical treatment. Paresthesia and hypoesthesia after GPA using HA filler are rare, and no cases of erectile dysfunction were encountered by Korean urologists. Jeong HG, Ahn ST, Kim JW, et al. Practice Patterns Among Korean Urologists for Glans Penis Augmentation Using Hyaluronic Acid Filler in the Management of Premature Ejaculation. Sex Med 2018;6:297-301.
    Language English
    Publishing date 2018-08-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2734882-9
    ISSN 2050-1161
    ISSN 2050-1161
    DOI 10.1016/j.esxm.2018.06.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Augmentation of glans penis using injectable hyaluronic acid gel.

    Moon, D G / Kwak, T I / Cho, H Y / Bae, J H / Park, H S / Kim, J J

    International journal of impotence research

    2003  Volume 15, Issue 6, Page(s) 456–460

    Abstract: ... of the glans penis. In experiment I, 0.2 cm(3) of hyaluronic acid gel (HA) was injected into the dermis ... suggest that hyaluronic acid gel can be easily injected into the lamina propria of the glans penis and ... Recently, injectable hyaluronic acid gel has been widely used in soft-tissue augmentation ...

    Abstract Recently, injectable hyaluronic acid gel has been widely used in soft-tissue augmentation. We performed this study to identify the feasibility of hyaluronic acid gel for the augmentation of the glans penis. In experiment I, 0.2 cm(3) of hyaluronic acid gel (HA) was injected into the dermis of the glans penis of 25 New Zealand white rabbits via a 30 G needle. At 3, 7, 14, 30, and 90 days after injection, histological changes of glans were studied, respectively. In experiment II, 0.5 cm(3) of HA was injected into the dermis of the glans penis of 14 Beagle dogs via a 27 G needle. At 6 months after injection, histological changes of the glans penis were also evaluated. At the time of autopsy, the lung, liver, and spleen were studied for systemic adverse reaction in each separate experiment. In experiment I, various sized cavities filled with amorphous basophilic materials were noted in the lamina propria and corpus spongiosum of the glans penis. All implants were positively stained on alcian blue. The intensity decreased in a time-dependent manner. Until 14 days, minimal inflammatory reactions were noted, but no signs of inflammation were identified at 90 days. With the gradual decrease of inflammation, fibrosis and deposition of collagen were noted. In experiment II, implants were well maintained at 6 months after injection in the lamina propria. Grade 1 of the inflammatory reaction was noted in one case. In both the experiments, all the specimens were free from any foreign body reaction and systemic adverse reactions. In conclusion, these results suggest that hyaluronic acid gel can be easily injected into the lamina propria of the glans penis and reside until 6 months. Injectable hyaluronic acid gel has a potential as a new bioimplant for the augmentation of the glans penis.
    MeSH term(s) Animals ; Biocompatible Materials/pharmacology ; Dogs ; Hyaluronic Acid/pharmacology ; Injections, Intradermal ; Male ; Penis/cytology ; Penis/drug effects ; Prostheses and Implants ; Rabbits
    Chemical Substances Biocompatible Materials ; Hyaluronic Acid (9004-61-9)
    Language English
    Publishing date 2003-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1034295-3
    ISSN 1476-5489 ; 0955-9930
    ISSN (online) 1476-5489
    ISSN 0955-9930
    DOI 10.1038/sj.ijir.3901058
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2910: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Long-term effects of glans penis augmentation using injectable hyaluronic acid gel for premature ejaculation.

    Kwak, T I / Jin, M H / Kim, J J / Moon, D G

    International journal of impotence research

    2008  Volume 20, Issue 4, Page(s) 425–428

    Abstract: The authors created the glans penis augmentation by injectable hyaluronic acid gel and reported ... of glans penis augmentation by filler, the implants were well maintained and effective for glans penis ...

    Abstract The authors created the glans penis augmentation by injectable hyaluronic acid gel and reported the 6-month result for premature ejaculation. In a total of 38 patients, long-term effects of 5 years were compared to those of 6 months in terms of residual volume of implants and efficacy on premature ejaculation. Maximal glandular circumference measured by tapeline significantly decreased by 15% (P<0.05) but mean patient's visual estimation (Gr 0-Gr 4) did not decrease (3.60 vs 3.56, P>0.05). Compared to 6-month follow-up, intravaginal ejaculatory latency time and vibratory threshold decreased at 5 years (P<0.05), but still well increased considering those of preaugmentation. Hence, 76% of patients and 63% of partners were still satisfied. There was no serious adverse reaction. In the 5-year long-term follow-up of glans penis augmentation by filler, the implants were well maintained and effective for glans penis hypersensitivity in premature ejaculation patients.
    MeSH term(s) Adult ; Ejaculation ; Erectile Dysfunction/physiopathology ; Erectile Dysfunction/surgery ; Female ; Gels ; Humans ; Hyaluronic Acid ; Injections ; Male ; Middle Aged ; Patient Satisfaction ; Penis/surgery ; Prostheses and Implants ; Time Factors
    Chemical Substances Gels ; Hyaluronic Acid (9004-61-9)
    Language English
    Publishing date 2008-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 1034295-3
    ISSN 1476-5489 ; 0955-9930
    ISSN (online) 1476-5489
    ISSN 0955-9930
    DOI 10.1038/ijir.2008.26
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2910: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top