Article: Health concerns regarding the effect of the COVID-19 pandemic on male fertility.
Clinical and experimental reproductive medicine
2021 Volume 48, Issue 3, Page(s) 189–193
Abstract: ... infertility. Since male infertility is an important problem, scientists are evaluating whether COVID-19 ... in 2019. The disease caused by SARS-CoV-2, coronavirus disease 2019 (COVID-19), has been found to be ... in the renin-angiotensin system and is widely secreted in several tissues, including the testis, which has raised concerns ...
| Abstract | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus found in China in 2019. The disease caused by SARS-CoV-2, coronavirus disease 2019 (COVID-19), has been found to be closely related to the cells that secrete angiotensin-converting enzyme 2 (ACE2). ACE2 is involved in the renin-angiotensin system and is widely secreted in several tissues, including the testis, which has raised concerns because organs with high expression of the ACE2 receptor are susceptible to infection. Analyses have shown that in testicular cells, such as spermatogonia, seminiferous duct cells, Sertoli cells, and Leydig cells, there is a high expression level of ACE2. Therefore, SARS-CoV-2 may damage male reproductive tissues and cause infertility. Since male infertility is an important problem, scientists are evaluating whether COVID-19 may influence male infertility through the ACE2 receptor. |
|---|---|
| Language | English |
| Publishing date | 2021-07-22 |
| Publishing country | Korea (South) |
| Document type | Journal Article |
| ZDB-ID | 2653899-4 |
| ISSN | 2233-8241 ; 2233-8233 |
| ISSN (online) | 2233-8241 |
| ISSN | 2233-8233 |
| DOI | 10.5653/cerm.2021.04378 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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