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  1. Article ; Online: Acute Pancreatitis in a Patient With COVID-19 After the Resolution of Respiratory Symptoms.

    Muhammad Abrar Jeelani, Hafiz / Sheikh, Muhammad Mubbashir / Samuel, Shirly Susan / Omotosho, Yetunde Bernice / Sharko, Artem / Albetar, Rami

    Journal of investigative medicine high impact case reports

    2021  Volume 9, Page(s) 23247096211024773

    Abstract: ... no other reported case of AP associated with COVID-19 after the respiratory symptoms are resolved ... respiratory symptoms. A diagnosis of AP complicated with COVID-19 was made after laboratory and imaging workup ... In this article, we present a patient with COVID-19, who came with intractable epigastric pain and resolved ...

    Abstract The gastrointestinal (GI) involvement, including acute pancreatitis (AP) from the novel coronavirus disease-2019 (COVID-19), is increasingly being reported. Recent evidence suggests that the pathogenesis of COVID-19 is mediated by the angiotensin-converting enzyme 2 (ACE-2) receptors and transmembrane protease serine 2 (TMPRSS2) for "priming," which is highly expressed in the pancreas. To our knowledge, there is no other reported case of AP associated with COVID-19 after the respiratory symptoms are resolved. In this article, we present a patient with COVID-19, who came with intractable epigastric pain and resolved respiratory symptoms. A diagnosis of AP complicated with COVID-19 was made after laboratory and imaging workup, which was successfully managed conservatively.
    MeSH term(s) Abdominal Pain/etiology ; Anti-Bacterial Agents/therapeutic use ; COVID-19/diagnosis ; Humans ; Leukocytosis/etiology ; Lipase/blood ; Male ; Pancreatitis/diagnosis ; Pancreatitis/therapy ; Piperacillin, Tazobactam Drug Combination/therapeutic use ; Tomography, X-Ray Computed ; Young Adult
    Chemical Substances Anti-Bacterial Agents ; Piperacillin, Tazobactam Drug Combination (157044-21-8) ; Lipase (EC 3.1.1.3)
    Language English
    Publishing date 2021-06-15
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2710326-2
    ISSN 2324-7096 ; 2324-7096
    ISSN (online) 2324-7096
    ISSN 2324-7096
    DOI 10.1177/23247096211024773
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Acute Pancreatitis in a Patient With COVID-19 After the Resolution of Respiratory Symptoms

    Hafiz Muhammad Abrar Jeelani MD / Muhammad Mubbashir Sheikh MD / Shirly Susan Samuel MD / Yetunde Bernice Omotosho MD / Artem Sharko MD / Rami Albetar MD

    Journal of Investigative Medicine High Impact Case Reports, Vol

    2021  Volume 9

    Abstract: ... no other reported case of AP associated with COVID-19 after the respiratory symptoms are resolved ... respiratory symptoms. A diagnosis of AP complicated with COVID-19 was made after laboratory and imaging workup ... In this article, we present a patient with COVID-19, who came with intractable epigastric pain and resolved ...

    Abstract The gastrointestinal (GI) involvement, including acute pancreatitis (AP) from the novel coronavirus disease-2019 (COVID-19), is increasingly being reported. Recent evidence suggests that the pathogenesis of COVID-19 is mediated by the angiotensin-converting enzyme 2 (ACE-2) receptors and transmembrane protease serine 2 (TMPRSS2) for “priming,” which is highly expressed in the pancreas. To our knowledge, there is no other reported case of AP associated with COVID-19 after the respiratory symptoms are resolved. In this article, we present a patient with COVID-19, who came with intractable epigastric pain and resolved respiratory symptoms. A diagnosis of AP complicated with COVID-19 was made after laboratory and imaging workup, which was successfully managed conservatively.
    Keywords Medicine (General) ; R5-920 ; Pathology ; RB1-214
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: An Uncommon Cause of Acute Pancreatitis in a Patient With COVID-19.

    Vara-Luiz, Francisco / Pé D'Arca Barbosa, Fábio / Antunes Albuquerque, Ana / Valada Marques, Ana / Spencer, Vanda

    Cureus

    2022  Volume 14, Issue 8, Page(s) e27910

    Abstract: ... pancreatitis. Supportive care and cessation of the offending drug led to the resolution of symptoms ... the chest radiography was suggestive of COVID-19 pneumonia. The patient started dexamethasone ... As steroids are used as part of the treatment of most COVID-19 patients, this case suggests the need ...

    Abstract Drug-induced pancreatitis is a rare though important condition that remains a diagnostic challenge. Most of the evidence relies on case reports, and clinicians should consider a high suspicion of the diagnosis after ruling out other causes. In particular, steroids are frequently used drugs that have recently been associated with acute pancreatitis. The authors present the case of a 60-year-old female admitted to the emergency room with a fever and shortness of breath. The SARS-CoV-2 test was positive, and the chest radiography was suggestive of COVID-19 pneumonia. The patient started dexamethasone because of respiratory failure. On Day 7, she developed epigastric pain radiating to the back and the amylase level was greater than 10 times the upper reference limit (1354 U/L). A detailed evaluation of the medical history, along with the exclusion of other possible etiologies confirmed the diagnosis of steroid-induced pancreatitis. Supportive care and cessation of the offending drug led to the resolution of symptoms. As steroids are used as part of the treatment of most COVID-19 patients, this case suggests the need to consider this entity, as a delay in the diagnosis may result in complications and prolonged hospital stay.
    Language English
    Publishing date 2022-08-12
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.27910
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Post-acute sensory neurological sequelae in patients with severe acute respiratory syndrome coronavirus 2 infection: the COVID-PN observational cohort study.

    Odozor, Chioma U / Kannampallil, Thomas / Ben Abdallah, Arbi / Roles, Kristen / Burk, Carrie / Warner, Benjamin C / Alaverdyan, Harutyun / Clifford, David B / Piccirillo, Jay F / Haroutounian, Simon

    Pain

    2022  Volume 163, Issue 12, Page(s) 2398–2410

    Abstract: ... neurological sequelae after the resolution of symptomatic COVID-19 illness, but the occurrence ... to determine the odds for neuropathy symptoms after adjusting for key baseline variables. A total of 1556 ... associated with higher occurrence of peripheral neuropathy symptoms, after adjusting for the history ...

    Abstract Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can cause neurological sequelae after the resolution of symptomatic COVID-19 illness, but the occurrence of peripheral neuropathy symptoms and cranial nerve dysfunction is unknown. This study aimed to characterize the occurrence and severity of pain and peripheral neuropathy symptoms in patients with SARS-CoV-2 infection. An observational cohort study included adults tested for a SARS-CoV-2 infection at an academic medical center (assigned as CV+ or control, based on test results). Thirty to 90 days after the index SARS-CoV-2 test, patients completed a web-based questionnaire assessing pain, peripheral neuropathy-related sensory symptoms, and symptoms in the distribution of cranial nerves (current symptoms, symptoms at testing and 2 weeks thereafter). Univariate analyses compared the outcomes between the groups. Multivariable analysis was used to determine the odds for neuropathy symptoms after adjusting for key baseline variables. A total of 1556 participants were included: 542 CV+ patients and 1014 control subjects. CV+ patients reported a higher occurrence of peripheral neuropathy symptoms in the extremities anytime within 90 days postinfection (28.8% vs 12.9%, odds ratio [OR] [95% confidence interval] = 2.72 [2.10-3.54]), as well as such symptoms persisting up to 90 days after infection (6.1% vs 1.9%, OR = 3.39 [1.91-6.03]). The occurrence of pain in the extremities was higher in the CV+ group (24.2% vs 9.8%, OR = 2.95 [2.21-3.91]). SARS-CoV-2 infection was also associated with higher occurrence of peripheral neuropathy symptoms, after adjusting for the history of chronic pain and neuropathy (OR = 3.19 [2.37-4.29]). The results suggest that SARS-CoV-2 infection was independently associated with an increased risk of pain and peripheral neuropathy symptoms.
    MeSH term(s) Adult ; Humans ; COVID-19/complications ; SARS-CoV-2 ; Cohort Studies ; Peripheral Nervous System Diseases ; Pain
    Language English
    Publishing date 2022-03-24
    Publishing country United States
    Document type Observational Study ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 193153-2
    ISSN 1872-6623 ; 0304-3959
    ISSN (online) 1872-6623
    ISSN 0304-3959
    DOI 10.1097/j.pain.0000000000002639
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Acute Transverse Myelitis Following COVID-19 Infection: A Rare Case From Saudi Arabia.

    Bakir, Mohamad / Rebh, Fatimah

    Cureus

    2021  Volume 13, Issue 9, Page(s) e17658

    Abstract: ... enhancement. The patient was discharged home with almost complete resolution of his symptoms for later follow ... myelitis, and the patient was started on pulse steroids for seven days. After the therapy, the condition ... a few cases of acute transverse myelitis (ATM) following severe acute respiratory syndrome coronavirus 2 (SARS ...

    Abstract Respiratory viral illnesses can lead to a wide variety of neurological complications. However, only a few cases of acute transverse myelitis (ATM) following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have been reported in the literature. Here, we report a case of ATM following SARS-CoV-2 infection in a 57-year-old male patient. The patient presented to the emergency room with lower abdominal pain, urinary retention, bilateral lower limbs weakness, and allodynia for the last four days. One week earlier, he had experienced fever, cough, and shortness of breath. On physical examination, he was vitally stable with sensory loss from the nipples down to the lower limbs bilaterally. His nasopharyngeal polymerase chain reaction for SARS-CoV-2 was positive. MRI of the spine showed an abnormal cord signal extending from the level of the D2 vertebra down to the conus medullaris. The main differential diagnosis was transverse myelitis, and the patient was started on pulse steroids for seven days. After the therapy, the condition of the patient improved with the restoration of power and sensory sensation in his lower limbs. A new MRI of the whole spine one month later showed normal morphology and signal intensity without any abnormal enhancement. The patient was discharged home with almost complete resolution of his symptoms for later follow-up in the clinic.
    Language English
    Publishing date 2021-09-02
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.17658
    Database MEDical Literature Analysis and Retrieval System OnLINE

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