Article: Understanding the implications of SARS-CoV-2 re-infections on immune response milieu, laboratory tests and control measures against COVID-19.
2021 Volume 7, Issue 1, Page(s) e05951
Abstract: ... on immune response milieu, diagnostic laboratory tests and control measures against COVID-19. ... Hence, this article sought to offer detailed biology of SARS-CoV-2 re-infections and their implications ... the fast and pandemic-scale spread of COVID-19, mutations in SARS-CoV-2 have raised new diagnostic ...
Abstract | Several months after the emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), cases of re-infection after recovery were reported. The extent and duration of protective immunity after SARS-CoV-2 infection is not fully understood. As such, the possibility of re-infection with SARS-CoV-2. Furthermore, cases of re-infection were mainly due to different variants or mutant SARS-CoV-2. Following the fast and pandemic-scale spread of COVID-19, mutations in SARS-CoV-2 have raised new diagnostic challenges which include the redesign of the oligonucleotide sequences used in RT-PCR assays to avoid potential primer-sample mismatches, and decrease sensitivities. Since the initial wave of the pandemic, some regions had experienced fresh outbreaks, predisposing people to be susceptible to SARS-CoV-2 re-infection. Hence, this article sought to offer detailed biology of SARS-CoV-2 re-infections and their implications on immune response milieu, diagnostic laboratory tests and control measures against COVID-19. |
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Language | English |
Publishing date | 2021-01-09 |
Publishing country | England |
Document type | Journal Article ; Review |
ZDB-ID | 2835763-2 |
ISSN | 2405-8440 |
ISSN | 2405-8440 |
DOI | 10.1016/j.heliyon.2021.e05951 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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