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  1. Article ; Online: Paranasal sinuses computed tomography findings in anosmia of COVID-19.

    Naeini, Ali Safavi / Karimi-Galougahi, Mahboobeh / Raad, Nasim / Ghorbani, Jahangir / Taraghi, Ayeh / Haseli, Sara / Mehrparvar, Golfam / Bakhshayeshkaram, Mehrdad

    American journal of otolaryngology

    2020  Volume 41, Issue 6, Page(s) 102636

    Abstract: ... causes of anosmia with computed tomography (CT) of paranasal sinuses.: Results: 49 patients ... Thus, mechanistic data are needed to elucidate the pathophysiological drivers of anosmia of COVID-19.: Methods ... We performed the current study in patients who presented with anosmia and COVID-19 as documented ...

    Abstract Objective: Olfactory dysfunction in coronavirus disease-2019 (COVID-19) is poorly understood. Thus, mechanistic data are needed to elucidate the pathophysiological drivers of anosmia of COVID-19.
    Methods: We performed the current study in patients who presented with anosmia and COVID-19 as documented by the polymerase chain reaction (PCR) assay between April 1st and May 15st, 2020. We assessed for the conductive causes of anosmia with computed tomography (CT) of paranasal sinuses.
    Results: 49 patients who presented with anosmia and positive PCR assay for COVID-19 were included. The average age was 45 ± 12.2 years. Complete anosmia was present in 85.7% of patients and 91.8% of patients reported sudden onset of olfactory dysfunction. Taste disturbance was common (75.5%). There were no significant pathological changes in the paranasal sinuses on CT scans. Olfactory cleft and ethmoid sinuses appeared normal while in other sinuses, partial opacification was detected only in some cases.
    Conclusion: We did not find significant mucosal changes or olfactory cleft abnormality on CT imaging in patients with anosmia of COVID-19. Conductive causes of anosmia (i.e., mucosal disease) do not seem play a significant role in anosmia of COVID-19.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Olfaction Disorders/virology ; Pandemics ; Paranasal Sinuses/diagnostic imaging ; Pneumonia, Viral/complications ; Prospective Studies ; SARS-CoV-2 ; Taste Disorders/virology ; Tomography, X-Ray Computed
    Keywords covid19
    Language English
    Publishing date 2020-07-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2020.102636
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Paranasal sinuses computed tomography findings in anosmia of COVID-19

    Naeini, Ali Safavi / Karimi-Galougahi, Mahboobeh / Raad, Nasim / Ghorbani, Jahangir / Taraghi, Ayeh / Haseli, Sara / Mehrparvar, Golfam / Bakhshayeshkaram, Mehrdad

    American Journal of Otolaryngology

    2020  Volume 41, Issue 6, Page(s) 102636

    Keywords Otorhinolaryngology ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 604541-8
    ISSN 0196-0709
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2020.102636
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1637: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Paranasal sinuses computed tomography findings in anosmia of COVID-19

    Naeini, Ali Safavi / Karimi-Galougahi, Mahboobeh / Raad, Nasim / Ghorbani, Jahangir / Taraghi, Ayeh / Haseli, Sara / Mehrparvar, Golfam / Bakhshayeshkaram, Mehrdad

    Am J Otolaryngol

    Abstract: ... causes of anosmia with computed tomography (CT) of paranasal sinuses. RESULTS: 49 patients who presented ... Thus, mechanistic data are needed to elucidate the pathophysiological drivers of anosmia of COVID-19. METHODS ... We performed the current study in patients who presented with anosmia and COVID-19 as documented ...

    Abstract OBJECTIVE: Olfactory dysfunction in coronavirus disease-2019 (COVID-19) is poorly understood. Thus, mechanistic data are needed to elucidate the pathophysiological drivers of anosmia of COVID-19. METHODS: We performed the current study in patients who presented with anosmia and COVID-19 as documented by the polymerase chain reaction (PCR) assay between April 1st and May 15st, 2020. We assessed for the conductive causes of anosmia with computed tomography (CT) of paranasal sinuses. RESULTS: 49 patients who presented with anosmia and positive PCR assay for COVID-19 were included. The average age was 45 ± 12.2 years. Complete anosmia was present in 85.7% of patients and 91.8% of patients reported sudden onset of olfactory dysfunction. Taste disturbance was common (75.5%). There were no significant pathological changes in the paranasal sinuses on CT scans. Olfactory cleft and ethmoid sinuses appeared normal while in other sinuses, partial opacification was detected only in some cases. CONCLUSION: We did not find significant mucosal changes or olfactory cleft abnormality on CT imaging in patients with anosmia of COVID-19. Conductive causes of anosmia (i.e., mucosal disease) do not seem play a significant role in anosmia of COVID-19.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #626761
    Database COVID19

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  4. Article ; Online: Olfactory Bulb MRI and Paranasal Sinus CT Findings in Persistent COVID-19 Anosmia.

    Kandemirli, Sedat Giray / Altundag, Aytug / Yildirim, Duzgun / Tekcan Sanli, Deniz Esin / Saatci, Ozlem

    Academic radiology

    2020  Volume 28, Issue 1, Page(s) 28–35

    Abstract: ... needed in COVID-19 anosmia in order to better understand underlying pathogenesis.: Material and methods ... in COVID-19 anosmia. There was a relatively high percentage of olfactory bulb degeneration. Further ... on olfactory bulb imaging in COVID-19 olfactory dysfunction. An imaging study with objective clinical correlation is ...

    Abstract Background and purpose: There is limited literature consisting of case reports or series on olfactory bulb imaging in COVID-19 olfactory dysfunction. An imaging study with objective clinical correlation is needed in COVID-19 anosmia in order to better understand underlying pathogenesis.
    Material and methods: We evaluated 23 patients with persistent COVID-19 olfactory dysfunction. Patients included in this study had a minimum 1-month duration between onset of olfactory dysfunction and evaluation. Olfactory functions were evaluated with Sniffin' Sticks Test. Paranasal sinus CTs and MRI dedicated to olfactory nerves were acquired. On MRI, quantitative measurements of olfactory bulb volumes and olfactory sulcus depth and qualitative assessment of olfactory bulb morphology, signal intensity, and olfactory nerve filia architecture were performed.
    Results: All patients were anosmic at the time of imaging based on olfactory test results. On CT, Olfactory cleft opacification was seen in 73.9% of cases with a mid and posterior segment dominance. 43.5% of cases had below normal olfactory bulb volumes and 60.9% of cases had shallow olfactory sulci. Of all, 54.2% of cases had changes in normal inverted J shape of the bulb. 91.3% of cases had abnormality in olfactory bulb signal intensity in the forms of diffusely increased signal intensity, scattered hyperintense foci or microhemorrhages. Evident clumping of olfactory filia was seen in 34.8% of cases and thinning with scarcity of filia in 17.4%. Primary olfactory cortical signal abnormality was seen in 21.7% of cases.
    Conclusion: Our findings indicate olfactory cleft and olfactory bulb abnormalities are seen in COVID-19 anosmia. There was a relatively high percentage of olfactory bulb degeneration. Further longitudinal imaging studies could shed light on the mechanism of olfactory neuronal pathway injury in COVID-19 anosmia.
    MeSH term(s) Anosmia ; COVID-19 ; Humans ; Magnetic Resonance Imaging ; Olfaction Disorders/diagnostic imaging ; Olfactory Bulb/diagnostic imaging ; Pandemics ; SARS-CoV-2 ; Tomography, X-Ray Computed
    Keywords covid19
    Language English
    Publishing date 2020-10-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1355509-1
    ISSN 1878-4046 ; 1076-6332
    ISSN (online) 1878-4046
    ISSN 1076-6332
    DOI 10.1016/j.acra.2020.10.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4594: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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    ab Jg. 2022: Lesesaal (EG)

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