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  1. Article: Cystic neoplasms of the pancreas: current diagnostic modalities and management.

    Ng, Dennis Z W / Goh, Brian K P / Tham, Elizabeth H W / Young, Stephanie M / Ooi, London Lucien P J

    Annals of the Academy of Medicine, Singapore

    2009  Volume 38, Issue 3, Page(s) 251–259

    Abstract: ... of the various investigative modalities in the management of cystic neoplasia of the pancreas. ... a diagnostic and therapeutic problem to the clinician. This paper discusses the role ... Cystic neoplasm of the pancreas is a relatively uncommon condition covering a wide spectrum ...

    Abstract Cystic neoplasm of the pancreas is a relatively uncommon condition covering a wide spectrum of pathology. The increasing incidence as a result of routine imaging tests in asymptomatic patients presents a diagnostic and therapeutic problem to the clinician. This paper discusses the role of the various investigative modalities in the management of cystic neoplasia of the pancreas.
    MeSH term(s) Cystadenoma/diagnosis ; Cystadenoma/therapy ; Pancreatic Neoplasms/diagnosis ; Pancreatic Neoplasms/therapy
    Language English
    Publishing date 2009-04-06
    Publishing country Singapore
    Document type Journal Article ; Review
    ZDB-ID 604527-3
    ISSN 0304-4602
    ISSN 0304-4602
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: An updated review on ablative treatment of pancreatic cystic lesions.

    Canakis, Andrew / Law, Ryan / Baron, Todd

    Gastrointestinal endoscopy

    2019  Volume 91, Issue 3, Page(s) 520–526

    Abstract: ... the patient's age, medical comorbidities, and surgical risks as well as the wishes of the patient. Current ... invasive alternative in treating pancreatic cystic lesions. This review focuses on the modalities ... of ethanol ablation, paclitaxel ablation, and radiofrequency ablation of pancreatic cystic lesions. ...

    Abstract Pancreatic cysts are common and often incidentally detected on abdominal imaging. Their prevalence in asymptomatic individuals depends on the screening modality used. The incidence of these lesions increases with age and may be detected in nearly half of elderly patients undergoing high-resolution magnetic resonance imaging. Some, but not all, pancreas cysts have malignant potential. The overall risk is small but induces significant anxiety for the patient. When determining management options, it is important to consider the patient's age, medical comorbidities, and surgical risks as well as the wishes of the patient. Current strategies include imaging surveillance or surgical resection. Before embarking on cyst surveillance, a clinician must factor in patients' risk of developing malignancy, their life expectancy, medical comorbidities, and if they are a surgical candidate. Surgery poses significant adverse events and mortality, whereas radiographic surveillance imposes healthcare costs and psychological distress to patients with the looming possibility of malignancy. The development and use of endoscopic ultrasound cyst ablation is a minimally invasive alternative in treating pancreatic cystic lesions. This review focuses on the modalities of ethanol ablation, paclitaxel ablation, and radiofrequency ablation of pancreatic cystic lesions.
    MeSH term(s) Ablation Techniques/methods ; Antineoplastic Agents/administration & dosage ; Drainage ; Endosonography ; Ethanol/administration & dosage ; Humans ; Injections, Intralesional ; Paclitaxel/administration & dosage ; Pancreas/diagnostic imaging ; Pancreas/surgery ; Pancreatic Cyst/diagnostic imaging ; Pancreatic Cyst/surgery ; Pancreatic Neoplasms/diagnostic imaging ; Pancreatic Neoplasms/surgery ; Radiofrequency Ablation/methods ; Sclerosing Solutions/administration & dosage ; Ultrasonography, Interventional
    Chemical Substances Antineoplastic Agents ; Sclerosing Solutions ; Ethanol (3K9958V90M) ; Paclitaxel (P88XT4IS4D)
    Language English
    Publishing date 2019-10-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2019.09.037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Degenerated Serous Cystic Tumor of the Pancreas: Case Report and Literature Review of an Aggressive Presentation of a Benign Tumor.

    Papazarkadas, Xenofon / Gialamas, Eleftherios / Hassan, Galab M / Chautems, Roland / Bornand, Aurelie / Puppa, Giacomo / Toso, Christian

    The American journal of case reports

    2022  Volume 23, Page(s) e936165

    Abstract: ... by non-surgical modalities. Although current guidelines and data from the literature provide ... BACKGROUND Serous cystic tumors of the pancreas are known to present a benign nature and course ... cystic adenomas of the pancreas, although generally considered benign neoplasms, may present ...

    Abstract BACKGROUND Serous cystic tumors of the pancreas are known to present a benign nature and course, not requiring surgery in the absence of symptoms. In rare cases, these benign tumors may present aggressive characteristics such as local infiltration and lymph node and distant metastases. In such cases, a surgical approach may be necessary. CASE REPORT We present the case of a 79-year-old woman with an asymptomatic cytologically suggested caudal serous cystic tumor infiltrating the spleen and the splenic vein. This tumor was discovered in a computed tomography scan in the setting of evaluating distant spreading of a primary malignant neoplasm of the rectum. Suspicious malignant signs on imaging dictated a surgical approach and a distal splenopancreatectomy was carried out in the same operative time as the transanal resection of the rectal lesion. The nature of the pancreatic neoplasm was confirmed by histology, but 2 lymph nodes out of 4 retrieved were positive. The postoperative course was uneventful. No adjuvant treatment was proposed. Imaging control 6 months after surgery was not indicative of relapse. CONCLUSIONS Serous cystic adenomas of the pancreas, although generally considered benign neoplasms, may present with characteristics of malignancy. Moreover, they may prove difficult to differentiate from other malignant neoplasms by non-surgical modalities. Although current guidelines and data from the literature provide controversial information regarding management of these clinical entities, in the presence of suspicious radiological aspects, surgical resection could be considered.
    MeSH term(s) Abdomen ; Aged ; Female ; Humans ; Neoplasm Recurrence, Local/pathology ; Pancreas ; Pancreatic Neoplasms/diagnostic imaging ; Pancreatic Neoplasms/surgery ; Tomography, X-Ray Computed
    Language English
    Publishing date 2022-08-15
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.936165
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Current management of cystic neoplasms of the pancreas.

    Carpizo, D R / Allen, P J / Brennan, M F

    The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland

    2008  Volume 6, Issue 5, Page(s) 298–307

    Abstract: ... to the management of these cystic neoplasms. We provide an overview of the key features in diagnosis and ... in predicting malignancy. Particular attention is given to the natural history and management of intraductal ... represent benign neoplasms; however, a significant fraction of these are pre-malignant or malignant ...

    Abstract Over the last decade there has been a dramatic increase in the number of patients identified with pancreatic cysts. This increase has been largely attributed to advances in imaging. The majority of these cysts represent benign neoplasms; however, a significant fraction of these are pre-malignant or malignant. Because the majority of these neoplasms are benign, many reports have advocated a selective approach to surgical resection. Here we review the literature that has contributed to the development of our approach to the management of these cystic neoplasms. We provide an overview of the key features in diagnosis and in predicting malignancy. Particular attention is given to the natural history and management of intraductal papillary mucinous neoplasms (IPMN).
    MeSH term(s) Combined Modality Therapy ; Cystadenoma/diagnosis ; Cystadenoma/radiotherapy ; Cystadenoma/surgery ; Diagnosis, Differential ; Diagnostic Imaging ; Humans ; Pancreatic Cyst/diagnosis ; Pancreatic Cyst/radiotherapy ; Pancreatic Cyst/surgery ; Pancreatic Neoplasms/diagnosis ; Pancreatic Neoplasms/radiotherapy ; Pancreatic Neoplasms/surgery
    Language English
    Publishing date 2008-10-15
    Publishing country Scotland
    Document type Journal Article ; Review
    ZDB-ID 2102927-1
    ISSN 1479-666X
    ISSN 1479-666X
    DOI 10.1016/s1479-666x(08)80055-8
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5756: Show issues Location:
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  5. Article ; Online: Outcome of Laparoscopic Surgery in Patients with Cystic Lesions in the Distal Pancreas

    Kim V Anonsen / Trond Buanes / Bard Ingvald Rosok / Truls Hauge / Bjorn Edwin

    JOP Journal of the Pancreas, Vol 16, Iss 3, Pp 266-

    2015  Volume 270

    Abstract: ... observation for selected neoplasms using imaging criteria. However, current imaging modalities lack diagnostic ... Context Recent guidelines for the management of cystic lesions of the pancreas recommend ... of laparoscopic distal pancreatic resections in all patients referred with potential pancreatic cystic neoplasms ...

    Abstract Context Recent guidelines for the management of cystic lesions of the pancreas recommend observation for selected neoplasms using imaging criteria. However, current imaging modalities lack diagnostic accuracy, and the indication for surgery is debated. Objective In this study we have explored the outcome of laparoscopic distal pancreatic resections in all patients referred with potential pancreatic cystic neoplasms, with histological diagnosis as endpoint. Methods Between 1997 and 2009 all patients referred to our tertiary referral centre having a cystic neoplasm of the distal pancreas accepted for surgery, were included in the present observational study. Results A total of 69 patients were included. Sixty two patients underwent distal pancreatectomies, in whom 19 were spleen-preserving, and 7 enucleations were performed. Two procedures were converted to open technique. The lesions removed in 27 patients (39%) were either malignant or premalignant. The final diagnoses were serous cystic neoplasm (n=29), mucinous cystic neoplasm (n=12), pseudocyst (n=11), solid pseudopapillary neoplasm (n=10), intraductal papillary mucinous neoplasm (n=5) and other (n=2). Overall morbidity was 33%; 56% of the complications were classified as mild. Fistula rate was 10%. One patient died postoperatively from a cerebral haemorrhage. Conclusion Most complications after laparoscopic distal resection of cystic pancreatic lesions are mild, but the proportion of patients with benign lesions (61%) has to be reduced by focused preoperative investigations. Endoscopic ultrasound examination (EUS), enabling aspiration of cyst fluid and fine needle aspiration is an additional option for the preoperative workup.
    Keywords Pancreas ; Diseases of the digestive system. Gastroenterology ; RC799-869 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R
    Subject code 610 ; 616
    Language English
    Publishing date 2015-05-01T00:00:00Z
    Publisher E S Burioni Ricerche Bibliografiche
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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