Article ; Online: Parvovirus B19 encephalitis presenting as immune restoration disease after highly active antiretroviral therapy for human immunodeficiency virus infection.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
2003 Volume 36, Issue 9, Page(s) 1191–1194
Abstract: ... for human immunodeficiency virus infection may be a consequence of the restoration of an immune response against opportunistic pathogens (i.e ... immune restoration disease [IRD]). We describe a young man who had AIDS complicated by parvovirus B19 ... Illness occurring during the initial months of highly active antiretroviral therapy (HAART ...
| Abstract | Illness occurring during the initial months of highly active antiretroviral therapy (HAART) for human immunodeficiency virus infection may be a consequence of the restoration of an immune response against opportunistic pathogens (i.e., immune restoration disease [IRD]). We describe a young man who had AIDS complicated by parvovirus B19 infection and RBC aplasia and who developed a painless, progressive dyspraxia of the left arm and an expressive dysphasia 4 weeks after commencing effective HAART. Neuroimaging demonstrated multiple right fronto-parietal lesions, and, following extensive investigations, including a brain biopsy, it was concluded that the brain lesions represented IRD associated with parvovirus B19 infection. |
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| MeSH term(s) | AIDS-Related Opportunistic Infections/virology ; Adult ; Anti-HIV Agents/therapeutic use ; Antiretroviral Therapy, Highly Active/adverse effects ; Encephalitis, Viral/etiology ; HIV Infections/complications ; HIV Infections/drug therapy ; Humans ; Immunity ; Male ; Parvoviridae Infections/etiology ; Parvovirus B19, Human ; Polymerase Chain Reaction | ||||||||||
| Chemical Substances | Anti-HIV Agents | ||||||||||
| Language | English | ||||||||||
| Publishing date | 2003-05-01 | ||||||||||
| Publishing country | United States | ||||||||||
| Document type | Case Reports ; Journal Article | ||||||||||
| ZDB-ID | 1099781-7 | ||||||||||
| ISSN | 1537-6591 ; 1058-4838 | ||||||||||
| ISSN (online) | 1537-6591 | ||||||||||
| ISSN | 1058-4838 | ||||||||||
| DOI | 10.1086/374603 | ||||||||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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