Article: Postintubation Decline in Oxygen Saturation Index Predicts Mortality in COVID-19: A Retrospective Pilot Study.
Critical care research and practice
2021 Volume 2021, Page(s) 6682944
Abstract: ... in oxygenation indices after intubation is predictive of mortality in COVID-19 patients. This time window is ... pilot study, we enrolled 68 critically ill mechanically ventilated adult patients with confirmed COVID-19 ... scale studies to confirm the prognostic value of the indices in COVID-19 patients are warranted. ...
| Abstract | Background: Acute respiratory failure from COVID-19 pneumonia is a major cause of death after SARS-CoV-2 infection. We investigated whether PaO Methods: In this single-centered retrospective pilot study, we enrolled 68 critically ill mechanically ventilated adult patients with confirmed COVID-19. Physiological variables were recorded on the day of intubation (day 0) and postintubation days 3 and 7. The association between physiological parameters, PaO Results: The ARDS severity indices were not statistically different on the day of intubation, suggesting similar baseline conditions in nonsurviving and surviving patients. However, these indices were significantly worse in the nonsurviving as compared to surviving patients on postintubation days 3 and 7. On intubation day 3, PaO Conclusions: Decline in oxygenation indices after intubation is predictive of mortality in COVID-19 patients. This time window is critical to the outcome of these patients and a possible target for future interventions. Future large-scale studies to confirm the prognostic value of the indices in COVID-19 patients are warranted. |
|---|---|
| Language | English |
| Publishing date | 2021-05-26 |
| Publishing country | Egypt |
| Document type | Journal Article |
| ZDB-ID | 2573849-5 |
| ISSN | 2090-1313 ; 2090-1305 |
| ISSN (online) | 2090-1313 |
| ISSN | 2090-1305 |
| DOI | 10.1155/2021/6682944 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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