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Article ; Online: Case series: COVID-19 in patients with mild to moderate myasthenia gravis in a National Referral Hospital in Indonesia.

Octaviana, Fitri / Yugo, Hardito Puspo / Safri, Ahmad Yanuar / Indrawati, Luh Ari / Wiratman, Winnugroho / Ayuningtyas, Triana / Hakim, Manfaluthy

eNeurologicalSci

2021  Volume 23, Page(s) 100332

Abstract: Background: During the COVID-19 pandemic, patients with myasthenia gravis (MG) are most likely ... symptoms.: Case description: We presented three patients with MG who contracted COVID-19 ... of severe infection. Furthermore, viral infection and some medications in COVID-19 may exacerbate MG ...

Abstract Background: During the COVID-19 pandemic, patients with myasthenia gravis (MG) are most likely to be affected by this situation. Corticosteroids and immunosuppressant agents increase the risk of severe infection. Furthermore, viral infection and some medications in COVID-19 may exacerbate MG symptoms.
Case description: We presented three patients with MG who contracted COVID-19. All of the patients had a favourable outcome. Only one patient who was not treated with corticosteroids or immunosuppressant therapy experienced deterioration of MG symptoms, while the other patients who received immunosuppressant therapy did not develop MG exacerbation. Surprisingly, azithromycin did not provoke myasthenic crisis (MC) in patients with normal MGFA classification.
Conclusion: Using immunosuppressant agents may not lead to MG deterioration and may not be related to unfavourable outcomes.
Language English
Publishing date 2021-02-22
Publishing country Netherlands
Document type Case Reports
ZDB-ID 2838045-9
ISSN 2405-6502 ; 2405-6502
ISSN (online) 2405-6502
ISSN 2405-6502
DOI 10.1016/j.ensci.2021.100332
Database MEDical Literature Analysis and Retrieval System OnLINE

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