Article ; Online: Activation of transient receptor potential melastatin 7 (TRPM7) channel increases basal autophagy and reduces amyloid β-peptide.
Biochemical and biophysical research communications
2017 Volume 493, Issue 1, Page(s) 494–499
Abstract: Cerebral accumulation of amyloid β-peptide (Aβ), which is produced from amyloid precursor protein ... APP), is the primary cause of Alzheimer's disease (AD). Autophagy recycles cellular components and ...
| Abstract | Cerebral accumulation of amyloid β-peptide (Aβ), which is produced from amyloid precursor protein (APP), is the primary cause of Alzheimer's disease (AD). Autophagy recycles cellular components and digests intracellular components including Aβ. The Ca |
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| MeSH term(s) | Amyloid beta-Peptides/metabolism ; Autophagy/physiology ; Calcium Signaling/physiology ; Cell Line ; Down-Regulation/physiology ; Humans ; Neurons/cytology ; Neurons/physiology | |||||
| Chemical Substances | Amyloid beta-Peptides | |||||
| Language | English | |||||
| Publishing date | 2017-11-04 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 205723-2 | |||||
| ISSN | 1090-2104 ; 0006-291X ; 0006-291X | |||||
| ISSN (online) | 1090-2104 ; 0006-291X | |||||
| ISSN | 0006-291X | |||||
| DOI | 10.1016/j.bbrc.2017.08.163 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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