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Article ; Online: Disease management in a patient diagnosed with COVID-19 disease during induction intravesical BCG therapy: A case report and review of the literature.

Ok, Fesih / Durmus, Emrullah

Urologia

2021  Volume 90, Issue 1, Page(s) 195–197

Abstract: Objective: To discuss the patient diagnosed with COVID-19 disease while receiving intravesical ... recommendations regarding the patient group diagnosed with COVID-19 while receiving intravesical BCG treatment ... in the light of the literature.: Patient and methods: A 52-year-old male patient, who received intravesical ...

Abstract Objective: To discuss the patient diagnosed with COVID-19 disease while receiving intravesical induction bacillus Calmette-Guérin (BCG) treatment for non-muscle-invasive bladder cancer, its management in the light of the literature.
Patient and methods: A 52-year-old male patient, who received intravesical BCG treatment for high-grade pT1 papillary urothelial carcinoma, presented 12 h after taking the fourth dose of induction therapy 38.2° fever and chills. The patient's reverse transcriptase-polymerase chain reaction test was positive, and Thorax CT imaging showed a few ground-glass pneumonic infiltrations in bilateral lung bases consistent with COVID-19 disease.
Results: Although international urology associations have current recommendations regarding the pandemic process, only one study has made specific recommendations regarding the patient group diagnosed with COVID-19 while receiving intravesical BCG treatment. According to this recommendation, we interrupted our patient's BCG treatment for 3 weeks and then completed the treatment for 6 weeks. A maintenance treatment not exceeding 1 year was planned.
Conclusion: This group of patients' recommendation is to delay BCG therapy for at least 3 weeks after initial symptoms to allow for complete recovery. Although the administration schedule varies, maintenance therapy is recommended for no more than 1 year.
MeSH term(s) Humans ; Male ; Middle Aged ; Adjuvants, Immunologic/therapeutic use ; Administration, Intravesical ; BCG Vaccine/therapeutic use ; Carcinoma, Transitional Cell/drug therapy ; Carcinoma, Transitional Cell/pathology ; COVID-19/diagnosis ; Disease Management ; Neoplasm Invasiveness ; Neoplasm Recurrence, Local ; Urinary Bladder Neoplasms/drug therapy ; Urinary Bladder Neoplasms/pathology
Chemical Substances Adjuvants, Immunologic ; BCG Vaccine
Language English
Publishing date 2021-03-12
Publishing country United States
Document type Review ; Case Reports ; Journal Article
ZDB-ID 204043-8
ISSN 1724-6075 ; 0376-0057 ; 0391-5603
ISSN (online) 1724-6075
ISSN 0376-0057 ; 0391-5603
DOI 10.1177/03915603211001670
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