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  1. Article: Clopidogrel-Induced Eosinophilic Colitis.

    Djahandideh Sheijani, Shirin / Calabrese, Francesco / Pasta, Andrea / Marabotto, Elisa / Bodini, Giorgia / Furnari, Manuele / Grillo, Federica / Mastracci, Luca / Savarino, Edoardo V / Savarino, Vincenzo / Giannini, Edoardo G

    ACG case reports journal

    2023  Volume 10, Issue 8, Page(s) e01118

    Abstract: Eosinophilic colitis is a rare condition characterized by histologic findings of high eosinophilic ... eosinophilic colitis associated with the use of clopidogrel was diagnosed. After clopidogrel discontinuation ...

    Abstract Eosinophilic colitis is a rare condition characterized by histologic findings of high eosinophilic infiltrate in the gut wall, typically presenting with diarrhea and abdominal pain. The etiology of this entity remains unclear because it can be primary or can occur secondarily to infections, drugs, or even in association with immune-mediated diseases. We present the case of a woman referred to our outpatient clinic for chronic diarrhea that had been worsening for months. Colonoscopy with biopsies was performed, and eosinophilic colitis associated with the use of clopidogrel was diagnosed. After clopidogrel discontinuation, a complete remission of the clinical and histological picture was observed.
    Language English
    Publishing date 2023-08-03
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000001118
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Eosinophilic pulmonary disease with ulcerative colitis: A case report.

    Li, Songtao / Fang, Mingliang / Guo, Hua / Yu, Tian / Wang, Jun / Li, Weiming / Huang, Yunong / Wang, Xichuan / Wu, Rongyi

    Medicine

    2024  Volume 103, Issue 17, Page(s) e37851

    Abstract: Rationale: Eosinophilic pulmonary disease (EPD) is a general term for a large group of diseases ... with complex etiology. Ulcerative colitis is an inflammatory bowel disease (IBD). Patients with IBD may have ... pulmonary involvement. We herein present a case of ulcerative colitis complicated with EPD.: Patient ...

    Abstract Rationale: Eosinophilic pulmonary disease (EPD) is a general term for a large group of diseases with complex etiology. Ulcerative colitis is an inflammatory bowel disease (IBD). Patients with IBD may have pulmonary involvement. We herein present a case of ulcerative colitis complicated with EPD.
    Patient concerns: A 34-year-old woman with ulcerative colitis presented with dry cough. She had peripheral eosinophilia and apical ground glass opacities on CT (computed tomography) of her chest. Antibiotic treatment was ineffective.
    Diagnoses: Lung biopsy revealed eosinophil infiltration in the alveolar space and interstitial space, so EPD was considered.
    Interventions: After oral administration of prednisone, the lung shadow on CT disappeared when the cough symptoms resolved. However, the symptoms recurred after drug withdrawal, and the lung shadow reappeared on imaging. The cough symptoms and lung shadow disappeared after oral prednisone was given again. Prednisone was slowly discontinued after 6 months of treatment.
    Outcomes: The patient stopped prednisone for half a year. No recurrence or abnormal CT findings were detected during the half-year follow-up.
    Lessons: The clinical manifestations of EPD are atypical, laboratory and imaging findings are not specific, and it is difficult to make a definite diagnosis before lung biopsy. The diagnosis depends on pathological examination. Glucocorticoid treatment is effective, but some patients may relapse after drug withdrawal. Active follow-up after glucocorticoid treatment is very important for identifying disease recurrence. Patients with IBD are relatively prone to developing EPD. The etiology of EPD is complex. In clinical practice, we need to make a diagnosis and differential diagnosis to clarify its etiology.
    MeSH term(s) Humans ; Female ; Adult ; Colitis, Ulcerative/complications ; Colitis, Ulcerative/diagnosis ; Colitis, Ulcerative/drug therapy ; Pulmonary Eosinophilia/diagnosis ; Pulmonary Eosinophilia/drug therapy ; Pulmonary Eosinophilia/etiology ; Prednisone/therapeutic use ; Prednisone/administration & dosage ; Tomography, X-Ray Computed ; Glucocorticoids/therapeutic use ; Glucocorticoids/administration & dosage ; Diagnosis, Differential
    Chemical Substances Prednisone (VB0R961HZT) ; Glucocorticoids
    Language English
    Publishing date 2024-05-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000037851
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Refractory Malignant Eosinophilic Colitis Leading to Ischemic Colitis.

    Awad, Christina / Bailes, Benjamin / Horn, Christian / Patel, Anish

    ACG case reports journal

    2023  Volume 10, Issue 2, Page(s) e00991

    Abstract: Eosinophilic colitis (EC) is the most uncommon disease within the spectrum of eosinophilic ... colitis. The patient was tried on multiple therapies, including a combination therapy of benralizumab and ...

    Abstract Eosinophilic colitis (EC) is the most uncommon disease within the spectrum of eosinophilic gastrointestinal disorders. Currently, there are no well-established diagnostic criteria and no approved Food and Drug Administration therapies. We discuss a case of a 30-year-old man with refractory malignant EC leading to ischemic colitis. The patient was tried on multiple therapies, including a combination therapy of benralizumab and vedolizumab, which were unsuccessful. Unfortunately, the patient ultimately required a total proctocolectomy. More studies need to be performed to treat patients with severe refractory cases of EC.
    Language English
    Publishing date 2023-02-16
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000000991
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Eosinophilic colitis: An entity on the rise.

    Remes-Troche, J M

    Revista de gastroenterologia de Mexico (English)

    2022  Volume 87, Issue 2, Page(s) 133–134

    MeSH term(s) Colitis/diagnostic imaging ; Enteritis ; Eosinophilia ; Gastritis ; Humans
    Language English
    Publishing date 2022-05-13
    Publishing country Mexico
    Document type Editorial
    ZDB-ID 2828765-4
    ISSN 2255-534X ; 2255-534X
    ISSN (online) 2255-534X
    ISSN 2255-534X
    DOI 10.1016/j.rgmxen.2022.01.001
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  5. Article ; Online: Eosinophilic colitis in adults.

    Macaigne, Gilles

    Clinics and research in hepatology and gastroenterology

    2020  Volume 44, Issue 5, Page(s) 630–637

    Abstract: Eosinophilic colitis (EoC) is a pathological entity associated with abnormal infiltration ... of colonic mucosa by eosinophilic polynuclear cells (Eo). This is a relatively common pathology in infants ...

    Abstract Eosinophilic colitis (EoC) is a pathological entity associated with abnormal infiltration of colonic mucosa by eosinophilic polynuclear cells (Eo). This is a relatively common pathology in infants and children under 2 years old, but is more rare and has been less studied in adults. EoC can be classified as primary or secondary. Primary EoC is, in the majority of cases, related to an allergic reaction, either IgE-mediated and capable of causing an anaphylactic-type food allergy, or not mediated by IgE and capable of giving rise to food enteropathy. The symptoms for adults with EoC are variable and non-specific, diarrhoea and abdominal pain being the most common signs. There is no histological consensus for the diagnosis of EoC. The presence of over 40 Eo per high-power field (×400) in at least two different colonic segments could be suggested as the criterion for the diagnosis. In adults with primary EoC, skin tests are of limited value and the response to a restrictive diet is less effective than in young children, given that IgE or non-IgE-mediated allergic reactions are rarely identified and EoC generally require medical treatment. There is no consensus on the treatment of EoC, but the potential efficacy of corticosteroids and budesonide has been demonstrated in the vast majority of cases studied.
    MeSH term(s) Adult ; Colitis/classification ; Colitis/complications ; Colitis/diagnosis ; Colitis/therapy ; Eosinophilia/classification ; Eosinophilia/complications ; Eosinophilia/diagnosis ; Eosinophilia/therapy ; Humans
    Language English
    Publishing date 2020-04-02
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 2594333-9
    ISSN 2210-741X ; 2210-7401
    ISSN (online) 2210-741X
    ISSN 2210-7401
    DOI 10.1016/j.clinre.2020.02.019
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  6. Article ; Online: Mycophenolate-induced eosinophilic colitis

    Mario Alberto Caviedes-Cleves / Ariel A. Arteta

    Iatreia, Vol 36, Iss 2, Pp 278-

    A case report

    2023  Volume 285

    Abstract: ... in organ transplant patients. Eosinophilic colitis due to mycophenolate is a recognized condition in patients ... edema and eosinophilic inflammatory in-filtrate in the lamina propria with microabscess formation ...

    Abstract Mycophenolate mofetil is a medication used for the prevention of allograft rejection in organ transplant patients. Eosinophilic colitis due to mycophenolate is a recognized condition in patients with a history of renal transplantation and persistent diarrhea, requiring a biopsy to achieve an appropriate diagnosis and treatment. The case of an 11-year-old boy with diarrhea is presented; colon biopsy showed edema and eosinophilic inflammatory in-filtrate in the lamina propria with microabscess formation, with epithelial and crypt damage. Because of the absence of another cause of the clinical case, mycophenolate was withdrawn from the treatment scheme, with re-solution of the symptoms. The Naranjo adverse drug reaction probability scale was definitive with a score of 10. The report contributes to the literature with the characterization of the histopathological findings in mycophenolate-induced colonic injury.
    Keywords colitis ; mycophenolic acid ; diarrhea ; Medicine ; R ; Medicine (General) ; R5-920
    Subject code 610
    Language Spanish
    Publishing date 2023-04-01T00:00:00Z
    Publisher Universidad de Antioquia
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Eosinophilic colitis - a distinct clinical entity?

    Ray, Katrina

    Nature reviews. Gastroenterology & hepatology

    2022  Volume 19, Issue 3, Page(s) 148

    MeSH term(s) Colitis/diagnosis ; Enteritis ; Eosinophilia/diagnosis ; Gastritis ; Humans
    Language English
    Publishing date 2022-01-31
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2493722-8
    ISSN 1759-5053 ; 1759-5045
    ISSN (online) 1759-5053
    ISSN 1759-5045
    DOI 10.1038/s41575-022-00583-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6020: Show issues Location:
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    Zs.MG 97: Show issues

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  8. Article ; Online: Histopathology of Eosinophilic Gastrointestinal Diseases Beyond Eosinophilic Esophagitis.

    Arva, Nicoleta C / Bernieh, Anas / Lopez-Nunez, Oscar / Pletneva, Maria / Yang, Guang-Yu / Collins, Margaret H

    Immunology and allergy clinics of North America

    2024  Volume 44, Issue 2, Page(s) 369–381

    Abstract: ... enteritis, and eosinophilic colitis (EoC), are chronic inflammatory conditions characterized by persistent ... Eosinophilic gastrointestinal diseases (EGID), such as eosinophilic gastritis (EoG), eosinophilic ... eosinophilic duodenitis (EoD) are strongly associated with food allergen triggers and T ...

    Abstract Eosinophilic gastrointestinal diseases (EGID), such as eosinophilic gastritis (EoG), eosinophilic enteritis, and eosinophilic colitis (EoC), are chronic inflammatory conditions characterized by persistent gastrointestinal symptoms and elevated levels of activated eosinophils in the gastrointestinal tract. EoG and eosinophilic duodenitis (EoD) are strongly associated with food allergen triggers and T
    MeSH term(s) Humans ; Eosinophilic Esophagitis/diagnosis ; Eosinophilic Esophagitis/therapy ; Enteritis/diagnosis ; Enteritis/therapy ; Gastritis/diagnosis ; Gastritis/therapy ; Inflammation ; Eosinophilia
    Language English
    Publishing date 2024-02-14
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 92606-1
    ISSN 1557-8607 ; 0889-8561
    ISSN (online) 1557-8607
    ISSN 0889-8561
    DOI 10.1016/j.iac.2024.01.008
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    Se 710: Show issues Location:
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  9. Article ; Online: Eosinophilic Colitis

    Byungha Cho / Seung-Myoung Son / Soon Man Yoon

    The Korean Journal of Gastroenterology, Vol 74, Iss 5, Pp 295-

    2019  Volume 297

    Keywords Medicine ; R
    Language English
    Publishing date 2019-11-01T00:00:00Z
    Publisher Jin Publishing & Printing Co.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Eosinophilic colitis

    Bárbara María Esquijarosa Roque / Ana Mercedes Guillén Cánova / Emilio Andrés Rodríguez Ramirez / Luis Enrique Echevarría Martínez / Lázaro Osmani Rico Esquijarosa

    Revista de Ciencias Médicas de Pinar del Río, Vol 23, Iss 4, Pp 568-

    2019  Volume 577

    Abstract: Introduction: eosinophilic colitis is a gastrointestinal disorder characterized by an inflammatory ... colitis and treated with corticosteroids, showing a satisfactory progression at 72 hours, with regression ... it was decided an exploratory laparotomy and colon biopsy. The patient was diagnosed with eosinophilic ...

    Abstract Introduction: eosinophilic colitis is a gastrointestinal disorder characterized by an inflammatory infiltration in the colon and rectum, with predominance of eosinophils, its clinical manifestation depends on the affected intestinal epithelium layer, the exclusive affectation of the colon is exceptional, intestinal obstruction is the most evident manifestation and it is a disease of complex diagnosis, where the histological study is conclusive. It is present from 1 to 20 inhabitants per 100.000, its etiology is imprecise, it has been determined that there is an important genetic and allergic component. Corticosteroids are the treatment of first choice. Case report: a 12-year-old patient, presented abdominal pain, distension and was admitted, evolved with clinical and radiological signs of a mechanical ileus with progressive worsening, it was decided an exploratory laparotomy and colon biopsy. The patient was diagnosed with eosinophilic colitis and treated with corticosteroids, showing a satisfactory progression at 72 hours, with regression of the clinical chart. Conclusion: it is rare and little study pathology, not frequently found, it affects the muscular layer as a type of intestinal obstruction, this should be taken into account as a differential diagnosis of acute abdomen in pediatric patients.
    Keywords pediatría.colitis ; obstrucción intestinal ; eosinofilia ; diarrea ; Medicine ; R ; Medicine (General) ; R5-920
    Subject code 610
    Language Spanish
    Publishing date 2019-06-01T00:00:00Z
    Publisher ECIMED
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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