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  1. Article ; Online: In

    Arcidiacono, Steven / Spangler, Joseph R / Litteral, Vaughn / Doherty, Laurel A / Stamps, Blake / Walper, Scott / Goodson, Michael / Soares, Jason W

    ACS biomaterials science & engineering

    2023  Volume 9, Issue 9, Page(s) 5176–5185

    Abstract: ... Of particular interest is introducing microbial sense and response functions; however, techniques for testing ...

    Abstract Synthetic biology provides a means of engineering tailored functions into probiotic bacteria. Of particular interest is introducing microbial sense and response functions; however, techniques for testing in physiologically relevant environments, such as those for the intended use, are still lacking. Typically, engineered probiotics are developed and tested in monoculture or in simplified cocultures still within ideal environments.
    MeSH term(s) Animals ; Humans ; Fermentation ; Escherichia coli/genetics ; Engineering ; Probiotics
    Language English
    Publishing date 2023-08-29
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ISSN 2373-9878
    ISSN (online) 2373-9878
    DOI 10.1021/acsbiomaterials.3c00630
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: {[In

    Huang, Xiao / Chen, Ye-Xin / Xue, Yuan / Wang, Ying-Chi / Ren, Qing-Hua / Liu, Wenlong / Wu, Jiajing / Guo, Sheng-Ping

    Inorganic chemistry

    2023  Volume 62, Issue 19, Page(s) 7160–7164

    Abstract: Hg-based chalcogenides possess diverse structures, large nonlinear-optical (NLO) responses, and ...

    Abstract Hg-based chalcogenides possess diverse structures, large nonlinear-optical (NLO) responses, and suitable birefringences, making them potentially suitable for numerous crucial criteria of practical application as infrared (IR) NLO crystals. Here, a new pentanary Hg-based sulfide K
    Language English
    Publishing date 2023-05-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/acs.inorgchem.3c01048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: In

    Hunt-Serracín, Augusto César / Kazi, Misha I / Boll, Joseph M / Boutte, Cara C

    Journal of bacteriology

    2021  Volume 204, Issue 2, Page(s) e0043421

    Abstract: The stringent response is a broadly conserved stress response system that exhibits functional ...

    Abstract The stringent response is a broadly conserved stress response system that exhibits functional variability across bacterial clades. Here, we characterize the role of the stringent factor Rel in the nontuberculous mycobacterial pathogen, Mycobacterium abscessus (
    MeSH term(s) Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Gene Expression Regulation, Bacterial ; Guanosine Pentaphosphate/biosynthesis ; Guanosine Pentaphosphate/metabolism ; Ligases/genetics ; Ligases/metabolism ; Mycobacterium abscessus/enzymology ; Mycobacterium abscessus/genetics ; Mycobacterium abscessus/metabolism
    Chemical Substances Bacterial Proteins ; Guanosine Pentaphosphate (38918-96-6) ; Ligases (EC 6.-) ; guanosine 3',5'-polyphosphate synthetases (EC 6.-)
    Language English
    Publishing date 2021-12-13
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2968-3
    ISSN 1098-5530 ; 0021-9193
    ISSN (online) 1098-5530
    ISSN 0021-9193
    DOI 10.1128/JB.00434-21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.50: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: In

    Kokkat, Johnson George / Shelvy, Sreekumar / Fayad, Abdulkabeer Muhammed / Shabeer T P, Ahammed / Umadevi, Palaniyandi / Kale, Rajaram / Angadi, Ulavappa Basavanneppa / Iquebal, Mir Asif / Jaiswal, Sarika / Rai, Anil / Kumar, Dinesh

    Journal of biomolecular structure & dynamics

    2021  Volume 40, Issue 14, Page(s) 6398–6404

    Abstract: Rotundone, an oxygenated sesquiterpene compound, responsible for the peppery aroma. The importance ...

    Abstract Rotundone, an oxygenated sesquiterpene compound, responsible for the peppery aroma. The importance of the rotundone in the flavor industry warrants search for the precursor genes in plants. We report in this study, the first on the identification of rotundone backbone genes viz., α-guaiene synthase & α-guaiene oxidase in black pepper. We identified the precursor genes of rotundone using berry transcriptome profiling. The metabolite profiling using head space mass spectrometry showed the presence of the direct precursor compounds for rotundone biosynthesis in black pepper berries. The identification of the genes & compounds of the guaiene skeleton is expected to help in bioprospecting of black pepper varieties & also in recombinant production of the aroma compound.Communicated by Ramaswamy H. Sarma [Formula: see text]Identification of rotundone backbone genes & precursor compounds from
    MeSH term(s) Fruit/chemistry ; Fruit/genetics ; Gas Chromatography-Mass Spectrometry/methods ; Odorants/analysis ; Piper nigrum/chemistry ; Piper nigrum/genetics ; Piper nigrum/metabolism ; Sesquiterpenes/analysis ; Sesquiterpenes/chemistry ; Sesquiterpenes/metabolism
    Chemical Substances Sesquiterpenes
    Language English
    Publishing date 2021-02-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2021.1883113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2093: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: In

    Llopis-Lorente, Jordi / Gomis-Tena, Julio / Cano, Jordi / Romero, Lucía / Saiz, Javier / Trenor, Beatriz

    Journal of chemical information and modeling

    2020  Volume 60, Issue 10, Page(s) 5172–5187

    Abstract: Drug-induced torsade de pointes (TdP) is a life-threatening ventricular arrhythmia responsible ...

    Abstract Drug-induced torsade de pointes (TdP) is a life-threatening ventricular arrhythmia responsible for the withdrawal of many drugs from the market. Although currently used TdP risk-assessment methods are effective, they are expensive and prone to produce false positives. In recent years,
    MeSH term(s) Action Potentials ; Arrhythmias, Cardiac/chemically induced ; Electrocardiography ; Humans ; Pharmaceutical Preparations ; Torsades de Pointes/chemically induced
    Chemical Substances Pharmaceutical Preparations
    Language English
    Publishing date 2020-08-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 190019-5
    ISSN 1549-960X ; 0095-2338
    ISSN (online) 1549-960X
    ISSN 0095-2338
    DOI 10.1021/acs.jcim.0c00201
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1230: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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