LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 3 of total 3

Search options

  1. Article ; Online: Staphylococcus epidermidis--the 'accidental' pathogen.

    Otto, Michael

    Nature reviews. Microbiology

    2009  Volume 7, Issue 8, Page(s) 555–567

    Abstract: Although nosocomial infections by Staphylococcus epidermidis have gained much attention, this skin ... relationship with its host. Accordingly, S. epidermidis does not produce aggressive virulence determinants ... Rather, factors that normally sustain the commensal lifestyle of S. epidermidis seem to give rise ...

    Abstract Although nosocomial infections by Staphylococcus epidermidis have gained much attention, this skin-colonizing bacterium has apparently evolved not to cause disease, but to maintain the commonly benign relationship with its host. Accordingly, S. epidermidis does not produce aggressive virulence determinants. Rather, factors that normally sustain the commensal lifestyle of S. epidermidis seem to give rise to additional benefits during infection. Furthermore, we are beginning to comprehend the roles of S. epidermidis in balancing the epithelial microflora and serving as a reservoir of resistance genes. In this Review, I discuss the molecular basis of the commensal and infectious lifestyles of S. epidermidis.
    MeSH term(s) Animals ; Anti-Bacterial Agents/pharmacology ; Biofilms/growth & development ; Drug Resistance/genetics ; Host-Pathogen Interactions ; Humans ; Skin/microbiology ; Staphylococcal Infections/microbiology ; Staphylococcus epidermidis/drug effects ; Staphylococcus epidermidis/pathogenicity ; Staphylococcus epidermidis/physiology ; Virulence
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2009-07-16
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Intramural ; Review
    ZDB-ID 2139054-X
    ISSN 1740-1534 ; 1740-1526
    ISSN (online) 1740-1534
    ISSN 1740-1526
    DOI 10.1038/nrmicro2182
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5865: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 74: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Comparative analysis between biofilm formation and gene expression in Staphylococcus epidermidis isolates.

    Freitas, Ana I / Lopes, Nathalie / Oliveira, Fernando / Brás, Susana / França, Ângela / Vasconcelos, Carlos / Vilanova, Manuel / Cerca, Nuno

    Future microbiology

    2018  Volume 13, Page(s) 415–427

    Abstract: ... in biofilm formation in selected clinical and commensal Staphylococcus epidermidis isolates.: Material ... commensal strains.: Conclusion: These results reinforce the concept that S. epidermidis is an 'accidental ... pathogen,' and that the ica operon is the main mechanism of biofilm formation in clinical and commensal ...

    Abstract Aim: To understand the relationship between ica, aap and bhp gene expression and the implications in biofilm formation in selected clinical and commensal Staphylococcus epidermidis isolates.
    Material & methods: Isolates were analyzed regarding their biofilm-forming capacity, biochemical matrix composition, biofilm spatial organization and expression of biofilm-related genes.
    Results: On polysaccharide intercellular adhesin-dependent biofilms, aap and bhp contributions for the biofilm growth were negligible, despite very high levels of expression. In contrast, smaller increases in icaA expression contributed significantly to biofilm growth. Interestingly, no biological differences were observed between clinical and commensal strains.
    Conclusion: These results reinforce the concept that S. epidermidis is an 'accidental pathogen,' and that the ica operon is the main mechanism of biofilm formation in clinical and commensal isolates.
    MeSH term(s) Bacterial Proteins/genetics ; Biofilms/growth & development ; Gene Expression/genetics ; Humans ; Polysaccharides, Bacterial/metabolism ; Staphylococcal Infections/microbiology ; Staphylococcus epidermidis/genetics ; Staphylococcus epidermidis/growth & development ; Staphylococcus epidermidis/isolation & purification ; Staphylococcus epidermidis/physiology ; Time Factors ; Transcription, Genetic
    Chemical Substances Bacterial Proteins ; Polysaccharides, Bacterial
    Language English
    Publishing date 2018-02-22
    Publishing country England
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1746-0921
    ISSN (online) 1746-0921
    DOI 10.2217/fmb-2017-0140
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article: Multiresistant Staphylococcus epidermidis as a pathogen.

    Heikkonen, L / Palmu, A / Böstman, O

    Annals of clinical research

    1986  Volume 18, Issue 2, Page(s) 80–83

    Abstract: ... of multiresistant strains of Staphylococcus epidermidis (MSE) at the departments of internal medicine ... in 155 patients, and in 115 of these (65% of the total) the MSE very probably was the true pathogen ... The multiresistant strains amounted to 57.9% of all recovered Staph. epidermidis strains. The mean age ...

    Abstract The purpose of this study was to examine the occurrence and the present clinical significance of multiresistant strains of Staphylococcus epidermidis (MSE) at the departments of internal medicine, general surgery, neurology and lung diseases of an university hospital. All those 178 consecutive in-patients from whom, during a half-year investigation period, a strain of MSE was isolated, were immediately enrolled in the study. A strain was defined as multiresistant if it was resistant to 3 or more antimicrobial agents. The clinical course of the patients was followed prospectively daily for any sign of infection. The multiresistant strains amounted to 57.9% of all recovered Staph. epidermidis strains. The mean age of the patients was 50.3 years. A chronic underlying disease was present in 97%. There was a clinical infection in 155 patients, and in 115 of these (65% of the total) the MSE very probably was the true pathogen. The distribution of these infections was as follows: wound infection in 49 (43%), urinary tract infection in 43 (37%), local soft tissue infection in 13 (11%) and septicaemia in 10 (9%) patients. In 40 patients (22% of the total) the role of the MSE in the infection remained uncertain and in 23 patients (13%) the finding obviously was an accidental skin contamination.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aminoglycosides/pharmacology ; Anti-Bacterial Agents/pharmacology ; Drug Resistance, Microbial ; Female ; Humans ; Male ; Middle Aged ; Nitroimidazoles/pharmacology ; Prospective Studies ; Staphylococcus epidermidis/drug effects ; Staphylococcus epidermidis/isolation & purification ; Staphylococcus epidermidis/pathogenicity
    Chemical Substances Aminoglycosides ; Anti-Bacterial Agents ; Nitroimidazoles
    Language English
    Publishing date 1986
    Publishing country Finland
    Document type Journal Article
    ZDB-ID 390317-5
    ISSN 0003-4762
    ISSN 0003-4762
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 680: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top