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  1. Article ; Online: Supplying synthetic opioids during a pandemic: An early look at North America.

    Pardo, Bryce

    The International journal on drug policy

    2020  Volume 93, Page(s) 102833

    Abstract: ... to buyers in North America. The magnitude of supply shortages and interrupted trade of chemicals and ... drugs like fentanyl and precursor chemicals supplied to North America from China, which may have ... may help save lives. The drug policy landscape could look different in a post-COVID world. ...

    Abstract International commerce and travel have been restricted in order to limit the spread of COVID-19. The illegal trafficking in drugs, which is often concealed in other commercial activity, will be affected by these disruptions. This is particularly true for precursor chemicals, controlled substances of synthetic origin, and new psychoactive substances coming from Asia. China hosts large and under-regulated pharmaceutical and chemical sectors that provide many of the active ingredients used both in legitimate medicines and illicit fentanyl and methamphetamine. Unregulated producers and vendors in China have been supplying drug trafficking organizations in Mexico or using the internet and postal service to directly sell fentanyl to buyers in North America. The magnitude of supply shortages and interrupted trade of chemicals and synthetic drugs coming from China will depend on the breadth and depth of COVID-19's disruptions. In turn, this could impact vulnerable drug-using populations. Drawing on historical accounts of prior supply disruptions, this commentary offers some initial speculation as to the possible effects of COVID-19 on the supply of synthetic drugs like fentanyl and precursor chemicals supplied to North America from China, which may have important lessons for other parts of the globe. Prior supply disruptions coincided with elevated prices and reduced purities of street drugs as well as increases in the number of users entering treatment. However, it is challenging to predict how developments will unfold given the unprecedented nature of this pandemic. A short-term breakdown in supply chains, interrupted trade, or social distancing mandates may not have much of an effect on the availability of synthetic drugs. Yet, disruptions in trade for months or years could shape how drugs are supplied or used. Drug policy will need to evaluate market indicators as soon as they are available but responding now with expanded medication therapies, like methadone, may help save lives. The drug policy landscape could look different in a post-COVID world.
    MeSH term(s) Analgesics, Opioid ; Asia ; COVID-19 ; China/epidemiology ; Humans ; Mexico ; North America ; Pandemics ; SARS-CoV-2
    Chemical Substances Analgesics, Opioid
    Keywords covid19
    Language English
    Publishing date 2020-10-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2010000-0
    ISSN 1873-4758 ; 0955-3959
    ISSN (online) 1873-4758
    ISSN 0955-3959
    DOI 10.1016/j.drugpo.2020.102833
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Supplying synthetic opioids during a pandemic: An early look at North America

    Pardo, Bryce

    Int J Drug Policy

    Abstract: ... to buyers in North America. The magnitude of supply shortages and interrupted trade of chemicals and ... drugs like fentanyl and precursor chemicals supplied to North America from China, which may have ... may help save lives. The drug policy landscape could look different in a post-COVID world. ...

    Abstract International commerce and travel have been restricted in order to limit the spread of COVID-19. The illegal trafficking in drugs, which is often concealed in other commercial activity, will be affected by these disruptions. This is particularly true for precursor chemicals, controlled substances of synthetic origin, and new psychoactive substances coming from Asia. China hosts large and under-regulated pharmaceutical and chemical sectors that provide many of the active ingredients used both in legitimate medicines and illicit fentanyl and methamphetamine. Unregulated producers and vendors in China have been supplying drug trafficking organizations in Mexico or using the internet and postal service to directly sell fentanyl to buyers in North America. The magnitude of supply shortages and interrupted trade of chemicals and synthetic drugs coming from China will depend on the breadth and depth of COVID-19's disruptions. In turn, this could impact vulnerable drug-using populations. Drawing on historical accounts of prior supply disruptions, this commentary offers some initial speculation as to the possible effects of COVID-19 on the supply of synthetic drugs like fentanyl and precursor chemicals supplied to North America from China, which may have important lessons for other parts of the globe. Prior supply disruptions coincided with elevated prices and reduced purities of street drugs as well as increases in the number of users entering treatment. However, it is challenging to predict how developments will unfold given the unprecedented nature of this pandemic. A short-term breakdown in supply chains, interrupted trade, or social distancing mandates may not have much of an effect on the availability of synthetic drugs. Yet, disruptions in trade for months or years could shape how drugs are supplied or used. Drug policy will need to evaluate market indicators as soon as they are available but responding now with expanded medication therapies, like methadone, may help save lives. The drug policy landscape could look different in a post-COVID world.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #893724
    Database COVID19

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