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  1. Article: COVID-19 infection and severe rhabdomyolysis.

    Patel, Vishal / Alzghoul, Bashar / Kalra, Saminder Singh

    Proceedings (Baylor University. Medical Center)

    2021  Volume 34, Issue 4, Page(s) 478–480

    Abstract: ... of multiorgan failure. The management of severe rhabdomyolysis and COVID-19 is challenging, and fluid ... Although patients with COVID-19 can have mild nonspecific myalgia and mild elevation of creatinine ... dark-colored urine, and a positive COVID-19 test. He had a prolonged hospital course requiring ...

    Abstract Although patients with COVID-19 can have mild nonspecific myalgia and mild elevation of creatinine kinase levels, severe myalgia along with elevation of creatinine kinase levels >10 times the upper normal limit and dark-colored urine indicate an underlying severe rhabdomyolysis. This report describes a 60-year-old morbidly obese man who was found to have severe rhabdomyolysis, along with acute kidney injury, dark-colored urine, and a positive COVID-19 test. He had a prolonged hospital course requiring continuous renal replacement therapy, mechanical ventilation, and multiple vasopressors and eventually died of multiorgan failure. The management of severe rhabdomyolysis and COVID-19 is challenging, and fluid resuscitation should be done cautiously, monitoring for early signs of fluid overload.
    Language English
    Publishing date 2021-03-23
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2703932-8
    ISSN 1525-3252 ; 0899-8280
    ISSN (online) 1525-3252
    ISSN 0899-8280
    DOI 10.1080/08998280.2021.1897341
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6987: Show issues Location:
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  2. Article: Non-ST Segment Elevation Myocardial Infarction (NSTEMI) in the Setting of Severe Rhabdomyolysis and COVID-19 Infection: A Case Report.

    Hassan, Mubariz A / Batta, Yashvardhan / Smith, Tori / Afzal, Muhammad Adil

    Cureus

    2023  Volume 15, Issue 6, Page(s) e40554

    Abstract: ... in an 89-year-old male with severe rhabdomyolysis and COVID-19 infection. The patient had a complex medical ... developed acute hypoxic respiratory failure and was treated for COVID-19 pneumonia. The patient's ... was found to be COVID-19 positive. Despite the absence of typical symptoms, the patient's elevated ...

    Abstract We present a case report of a non-ST segment elevation myocardial infarction (NSTEMI) occurring in an 89-year-old male with severe rhabdomyolysis and COVID-19 infection. The patient had a complex medical history, including non-ischemic cardiomyopathy, sinus bradycardia status post permanent pacemaker placement, and multiple comorbidities. He presented to the emergency department after a mechanical fall and was found to be COVID-19 positive. Despite the absence of typical symptoms, the patient's elevated troponin levels and electrocardiogram findings indicated NSTEMI. The initial management included an acute coronary syndrome protocol and admission to the cardiac intensive care unit. During the hospitalization, the patient developed acute hypoxic respiratory failure and was treated for COVID-19 pneumonia. The patient's renal function and creatine kinase levels showed improvement, and cardiac catheterization revealed non-obstructive coronaries. The patient was discharged in stable condition with a follow-up scheduled.
    Language English
    Publishing date 2023-06-17
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.40554
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Rhabdomyolysis and acute kidney injury in severe COVID-19 infection.

    Taxbro, Knut / Kahlow, Hannes / Wulcan, Hannes / Fornarve, Anna

    BMJ case reports

    2020  Volume 13, Issue 9

    Abstract: ... for intubation and mechanical ventilation. Severe rhabdomyolysis and acute kidney injury developed 4 days later ... SARS-CoV-2-induced myositis with severe rhabdomyolysis and kidney failure. The patient survived and was ... myalgia, nausea, vomiting, dry cough, breathlessness and abdominal pain. He was admitted due to hypoxaemia ...

    Abstract We report the case of a 38-year-old man who presented to the emergency department with fever, myalgia, nausea, vomiting, dry cough, breathlessness and abdominal pain. He was admitted due to hypoxaemia and was diagnosed with SARS-CoV-2 and was subsequently referred to the intensive care unit for intubation and mechanical ventilation. Severe rhabdomyolysis and acute kidney injury developed 4 days later and were suspected after noticing discolouration of the urine and a marked increase in plasma myoglobin levels. Treatment included hydration, forced diuresis and continuous renal replacement therapy. In addition to the coronavirus disease acute respiratory distress syndrome, he was diagnosed with possible SARS-CoV-2-induced myositis with severe rhabdomyolysis and kidney failure. The patient survived and was discharged from intensive care after 12 days, returning home 23 days after hospitalisation, fully mobilised with a partially restored kidney function.
    MeSH term(s) Acute Disease ; Acute Kidney Injury/diagnosis ; Acute Kidney Injury/etiology ; Acute Kidney Injury/therapy ; Adult ; Anti-Bacterial Agents/therapeutic use ; Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/therapy ; Humans ; Male ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; Renal Replacement Therapy/methods ; Rhabdomyolysis/diagnosis ; Rhabdomyolysis/etiology ; Rhabdomyolysis/therapy ; SARS-CoV-2 ; Treatment Outcome
    Chemical Substances Anti-Bacterial Agents
    Keywords covid19
    Language English
    Publishing date 2020-09-02
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2020-237616
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Rhabdomyolysis and severe biphasic disturbance of calcium homeostasis secondary to COVID-19 infection.

    Li, Adrian Po Zhu / Thomas, Stephen / Gokmen, Refik / Kariyawasam, Dulmini

    BMJ case reports

    2021  Volume 14, Issue 5

    Abstract: We report a case of severe hypercalcaemia secondary to rhabdomyolysis in a woman with COVID-19 ... SARS CoV-2) infection. The patient presented with myalgia and anuria with an acute kidney injury ... with initial severe hypocalcaemia followed by severe, symptomatic hypercalcaemia, persistent despite ...

    Abstract We report a case of severe hypercalcaemia secondary to rhabdomyolysis in a woman with COVID-19 (SARS CoV-2) infection. The patient presented with myalgia and anuria with an acute kidney injury requiring haemodialysis. Creatine kinase peaked at 760 000 IU/L. A biphasic calcaemic response was observed with initial severe hypocalcaemia followed by severe, symptomatic hypercalcaemia, persistent despite haemodialysis. Control of the calcium levels was achieved by continuous haemofiltration.
    MeSH term(s) Acute Kidney Injury/etiology ; Acute Kidney Injury/therapy ; COVID-19 ; Calcium ; Female ; Homeostasis ; Humans ; Rhabdomyolysis/etiology ; SARS-CoV-2
    Chemical Substances Calcium (SY7Q814VUP)
    Language English
    Publishing date 2021-05-24
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2020-239611
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Rhabdomyolysis and acute kidney injury in severe COVID-19 infection

    Taxbro, Knut / Kahlow, Hannes / Wulcan, Hannes / Fornarve, Anna

    BMJ case reports

    Abstract: ... for intubation and mechanical ventilation. Severe rhabdomyolysis and acute kidney injury developed 4 days later ... SARS-CoV-2-induced myositis with severe rhabdomyolysis and kidney failure. The patient survived and was ... myalgia, nausea, vomiting, dry cough, breathlessness and abdominal pain. He was admitted due to hypoxaemia ...

    Abstract We report the case of a 38-year-old man who presented to the emergency department with fever, myalgia, nausea, vomiting, dry cough, breathlessness and abdominal pain. He was admitted due to hypoxaemia and was diagnosed with SARS-CoV-2 and was subsequently referred to the intensive care unit for intubation and mechanical ventilation. Severe rhabdomyolysis and acute kidney injury developed 4 days later and were suspected after noticing discolouration of the urine and a marked increase in plasma myoglobin levels. Treatment included hydration, forced diuresis and continuous renal replacement therapy. In addition to the coronavirus disease acute respiratory distress syndrome, he was diagnosed with possible SARS-CoV-2-induced myositis with severe rhabdomyolysis and kidney failure. The patient survived and was discharged from intensive care after 12 days, returning home 23 days after hospitalisation, fully mobilised with a partially restored kidney function.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #744834
    Database COVID19

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  6. Article ; Online: Rhabdomyolysis and acute kidney injury in severe COVID-19 infection

    Taxbro, Knut / Kahlow, Hannes / Wulcan, Hannes / Fornarve, Anna

    BMJ Case Reports

    2020  Volume 13, Issue 9, Page(s) e237616

    Abstract: ... for intubation and mechanical ventilation. Severe rhabdomyolysis and acute kidney injury developed 4 days later ... SARS-CoV-2-induced myositis with severe rhabdomyolysis and kidney failure. The patient survived and was ... myalgia, nausea, vomiting, dry cough, breathlessness and abdominal pain. He was admitted due to hypoxaemia ...

    Abstract We report the case of a 38-year-old man who presented to the emergency department with fever, myalgia, nausea, vomiting, dry cough, breathlessness and abdominal pain. He was admitted due to hypoxaemia and was diagnosed with SARS-CoV-2 and was subsequently referred to the intensive care unit for intubation and mechanical ventilation. Severe rhabdomyolysis and acute kidney injury developed 4 days later and were suspected after noticing discolouration of the urine and a marked increase in plasma myoglobin levels. Treatment included hydration, forced diuresis and continuous renal replacement therapy. In addition to the coronavirus disease acute respiratory distress syndrome, he was diagnosed with possible SARS-CoV-2-induced myositis with severe rhabdomyolysis and kidney failure. The patient survived and was discharged from intensive care after 12 days, returning home 23 days after hospitalisation, fully mobilised with a partially restored kidney function.
    Keywords covid19
    Language English
    Publisher BMJ
    Publishing country uk
    Document type Article ; Online
    ISSN 1757-790X
    DOI 10.1136/bcr-2020-237616
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Persistent post-COVID-19 neuromuscular symptoms.

    Abrams, Rory M C / Zhou, Lan / Shin, Susan C

    Muscle & nerve

    2023  Volume 68, Issue 4, Page(s) 350–355

    Abstract: ... regarding the evaluation and management of patients with persistent post-COVID-19 neuromuscular symptoms. ... with long COVID, also known as post-COVID-19 conditions or postacute sequelae of SARS-CoV-2 infection ... neuromuscular complications of coronavirus disease-2019 (COVID-19), such as Guillain-Barré syndrome ...

    Abstract Neuromuscular symptoms may develop or persist after resolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Besides residual sensorimotor symptoms associated with acute neuromuscular complications of coronavirus disease-2019 (COVID-19), such as Guillain-Barré syndrome, critical illness neuromyopathy, and rhabdomyolysis, patients may report persistent autonomic symptoms, sensory symptoms, and muscle symptoms in the absence of these acute complications, including palpitations, orthostatic dizziness and intolerance, paresthesia, myalgia, and fatigue. These symptoms may be associated with long COVID, also known as post-COVID-19 conditions or postacute sequelae of SARS-CoV-2 infection, which may significantly impact quality of life. Managing these symptoms represents a challenge for health-care providers. Recent advances have identified small-fiber neuropathy as a potential etiology that may underlie autonomic dysfunction and paresthesia in some long COVID patients. The pathogenic mechanisms underlying myalgia and fatigue remain elusive and need to be investigated. Herein we review the current state of knowledge regarding the evaluation and management of patients with persistent post-COVID-19 neuromuscular symptoms.
    MeSH term(s) Humans ; COVID-19/complications ; SARS-CoV-2 ; Post-Acute COVID-19 Syndrome ; Myalgia/etiology ; Paresthesia/etiology ; Quality of Life ; Fatigue/etiology ; Primary Dysautonomias
    Language English
    Publishing date 2023-07-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 438353-9
    ISSN 1097-4598 ; 0148-639X
    ISSN (online) 1097-4598
    ISSN 0148-639X
    DOI 10.1002/mus.27940
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1449: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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    Zs.MO 551: Show issues

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  8. Article: Rhabdomyolysis Secondary to COVID-19 Vaccination.

    Mack, Mariah / Nichols, Laura / Guerrero, Dubert M

    Cureus

    2021  Volume 13, Issue 5, Page(s) e15004

    Abstract: ... dose of the Moderna COVID-19 vaccine. He presented with severe weakness, myalgias, and an initial ... infection, but few cases of rhabdomyolysis associated with COVID-19 vaccination have been reported ... Rhabdomyolysis has been described as a complication of coronavirus disease 2019 (COVID-19 ...

    Abstract Rhabdomyolysis has been described as a complication of coronavirus disease 2019 (COVID-19) infection, but few cases of rhabdomyolysis associated with COVID-19 vaccination have been reported. We described a case of an 80-year-old male who developed rhabdomyolysis two days after receiving his second dose of the Moderna COVID-19 vaccine. He presented with severe weakness, myalgias, and an initial creatinine kinase (CK) of 6,546 IU/L that improved with intravenous fluids. Common causes of rhabdomyolysis were excluded including statin use, strenuous exercise, and trauma. With the increasing immunization efforts against COVID-19, physicians should consider the possibility of rhabdomyolysis when a patient presents with neuromuscular complaints following vaccination.
    Language English
    Publishing date 2021-05-13
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.15004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Fatal rhabdomyolysis caused by COVID-19 infection: a case report.

    Khalayli, Naram / Ibrahim, Raghad / Ibrahim, Rahaf / Kudsi, Maysoun

    Annals of medicine and surgery (2012)

    2023  Volume 85, Issue 7, Page(s) 3683–3685

    Abstract: COVID-19 is a systemic viral disease complicated with medical conditions. Severe rhabdomyolysis ... year-old female with fatal rhabdomyolysis caused by COVID-19 infection. She was referred ... in the COVID-19 isolation department. Three days later, she was transferred to the intensive care unit and ...

    Abstract COVID-19 is a systemic viral disease complicated with medical conditions. Severe rhabdomyolysis during the COVID-19 course is not until now well known.
    Case presentation: The authors presented a 48-year-old female with fatal rhabdomyolysis caused by COVID-19 infection. She was referred to us with cough, generalized myalgia and arthralgia, and fever during the last week. Laboratory results showed an elevated erythrocyte sedimentation rate, elevated C-reactive protein level, and elevated creatine kinase. The nasopharyngeal swab confirmed the diagnosis of coronavirus 2 RNA infection. She was managed initially in the COVID-19 isolation department. Three days later, she was transferred to the intensive care unit and mechanically ventilated. Laboratory results were consistent with rhabdomyolysis. She died because of cardiac arrest due to continuous hemodynamic deterioration.
    Clinical discussion: Rhabdomyolysis is a serious condition that can be fatal or cause disability. Rhabdomyolysis cases have been reported in COVID-19 patients.
    Conclusion: Rhabdomyolysis cases have been reported in COV19 patients. Further studies are needed to understand the mechanism and to optimize the treatment.
    Language English
    Publishing date 2023-06-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2745440-X
    ISSN 2049-0801
    ISSN 2049-0801
    DOI 10.1097/MS9.0000000000000881
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Extremely Elevated Creatine Kinase in COVID-19-Associated Rhabdomyolysis.

    Laches, Rachel E / Tillotson, Sophie / Kaufman, Erin / As Sayaideh, Mohammad

    Cureus

    2023  Volume 15, Issue 9, Page(s) e45448

    Abstract: ... with rhabdomyolysis associated with coronavirus disease 2019 (COVID-19) infection who developed excessively high ... Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) have been associated with rhabdomyolysis with varying degrees ... with the release of myoglobin and creatine kinase into the blood. Viral infections such as influenza and ...

    Abstract Rhabdomyolysis is a condition characterized by the destruction of skeletal muscle cells with the release of myoglobin and creatine kinase into the blood. Viral infections such as influenza and Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) have been associated with rhabdomyolysis with varying degrees of morbidity and mortality. We present the case of a male in his early thirties who was diagnosed with rhabdomyolysis associated with coronavirus disease 2019 (COVID-19) infection who developed excessively high creatine kinase levels, peaking at 1,650,000 U/L. He was treated with IV fluids and made a complete recovery.
    Language English
    Publishing date 2023-09-18
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.45448
    Database MEDical Literature Analysis and Retrieval System OnLINE

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