Article ; Online: Skin manifestations in COVID-19 patients, state of the art. A systematic review.
International journal of dermatology
2021 Volume 60, Issue 5, Page(s) 547–553
Abstract: ... a systematic review to evaluate skin involvement in COVID-19.: Methods: The authors performed a systematic ... with suspect of COVID-19 were examined. The mean age was 37.8 (range 0-91) years. Among the analyzed patients ... highlights the importance of skin involvement in COVID-19. Limbs should be examined to eventually foresee ...
| Abstract | Introduction: Since COVID-19 has become a pandemic, extensive literature has been produced. The commonest symptoms of COVID-19 disease are fever, cough, anosmia, and lymphocytopenia. However, other apparently less common clinical symptoms have been described, including skin lesions. We conducted a systematic review to evaluate skin involvement in COVID-19. Methods: The authors performed a systematic review of literature, in accordance with the Preferred Reporting Items for Systematic and Meta-Analysis (PRISMA). The search was reiterated until May 06, 2020. Results: Overall, 1593 patients (M/F ratio: 1 : 9) with suspect of COVID-19 were examined. The mean age was 37.8 (range 0-91) years. Among the analyzed patients, 84 (5.3%) were pediatrics (<18 years). Chilblains are very common among skin lesions and represent almost half of all skin lesions reported (46%); in 75% of patients with cutaneous manifestation, the latter presented before other typical clinical manifestation of COVID-19. Vasculitis or thrombosis was identified in almost 70% of patients who suffered from skin manifestations. Conclusion: The present study highlights the importance of skin involvement in COVID-19. Limbs should be examined to eventually foresee the onset of further typical symptoms. Chilblains can be considered typical features. Studies with higher scientific evidence are required. |
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| MeSH term(s) | COVID-19/complications ; Chilblains/epidemiology ; Chilblains/virology ; Humans ; Pandemics ; Skin Diseases/epidemiology ; Skin Diseases/virology ; Thrombosis/epidemiology ; Thrombosis/virology ; Vasculitis/epidemiology ; Vasculitis/virology | |||||
| Language | English | |||||
| Publishing date | 2021-02-02 | |||||
| Publishing country | England | |||||
| Document type | Journal Article ; Meta-Analysis ; Review ; Systematic Review | |||||
| ZDB-ID | 412254-9 | |||||
| ISSN | 1365-4632 ; 0011-9059 ; 1461-1244 | |||||
| ISSN (online) | 1365-4632 | |||||
| ISSN | 0011-9059 ; 1461-1244 | |||||
| DOI | 10.1111/ijd.15414 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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