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  1. Article ; Online: COVID-19 infection in infant with severe CHD.

    Pexton, Natalie / Svenson, Amy / Bhat, Deepti

    Cardiology in the young

    2021  Volume 31, Issue 10, Page(s) 1704–1705

    Abstract: ... with fever and vomiting and was found to be infected with the novel corona virus (COVID-19). He underwent ...

    Abstract We describe the case of a 2-month-old born with hypoplastic left heart syndrome who presented with fever and vomiting and was found to be infected with the novel corona virus (COVID-19). He underwent treatment with supplemental oxygen, heparin, and dexamethasone. After a 6-day hospitalisation, he recovered remarkably well without major adverse effects.
    MeSH term(s) COVID-19 ; Fever ; Hospitalization ; Humans ; Infant ; Male ; SARS-CoV-2
    Language English
    Publishing date 2021-03-18
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1078466-4
    ISSN 1467-1107 ; 1047-9511
    ISSN (online) 1467-1107
    ISSN 1047-9511
    DOI 10.1017/S1047951121001384
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: COVID-19 in Cyanotic Congenital Heart Disease.

    Ammar, Lama A / Nassar, Joseph E / Bitar, Fadi / Arabi, Mariam

    The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

    2023  Volume 2023, Page(s) 5561159

    Abstract: ... disease 2019 (COVID-19) in cyanotic CHD patients. The infection may directly or indirectly affect ... risk of mortality from COVID-19 infection or suffering worse complications. While the anatomic ... volume-overloaded in the context of CHD is theoretically more severe. Patients with CHD are at a higher ...

    Abstract Congenital heart disease (CHD) is the most prevalent congenital defect in newborn infants. Due to the various types of heart abnormalities, CHD can have a wide range of symptoms. Cardiac lesions comprise a range of different types and accordingly varying severities. It is highly helpful to classify CHD into cyanotic and acyanotic heart diseases. In this review, we are investigating the course of Coronavirus disease 2019 (COVID-19) in cyanotic CHD patients. The infection may directly or indirectly affect the heart by affecting the respiratory system and other organs. The effect on the heart that is pressure- or volume-overloaded in the context of CHD is theoretically more severe. Patients with CHD are at a higher risk of mortality from COVID-19 infection or suffering worse complications. While the anatomic complexity of CHD does not seem to predict the severity of infection, patients with worse physiological stages are more susceptible such as cyanosis and pulmonary hypertension. Patients with CHD exhibit continuous hypoxemia and have lower oxygen saturations because of a right-to-left shunt. Such individuals run the danger of rapidly deteriorating in the event of respiratory tract infections with inadequate oxygenation. Additionally, these patients have a higher risk of paradoxical embolism. Hence, critical care should be given to cyanotic heart disease patients with COVID-19 in comparison to acyanotic patients and this is through proper management, close observation, and adequate medical therapy.
    Language English
    Publishing date 2023-04-18
    Publishing country Egypt
    Document type Journal Article ; Review
    ZDB-ID 1057056-1
    ISSN 1712-9532 ; 1180-2332
    ISSN 1712-9532 ; 1180-2332
    DOI 10.1155/2023/5561159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Perioperative care of the newborns with CHDs in the time of COVID-19.

    Dilli, Dilek / Taşoğlu, Irfan

    Cardiology in the young

    2020  Volume 30, Issue 7, Page(s) 946–954

    Abstract: ... of COVID-19 on patients with cardiovascular disease, especially for those with CHD. Herein, we aimed ... to summarise the COVID-19-specific perioperative management issues for newborns with CHD by combining available ... to an unexpected outbreak affecting people of all ages. The first data showed that COVID-19 could cause severe ...

    Abstract Coronavirus disease 2019 (COVID-19), caused by a novel betacoronavirus (SARS-CoV-2), has led to an unexpected outbreak affecting people of all ages. The first data showed that COVID-19 could cause severe pulmonary disease, cardiac injury, and death in adults, especially the elderly and those with concomitant diseases. Currently, it was demonstrated that severe COVID-19 may also develop in neonatal age, although rarely. Newborns with CHD are known to be at high risk for increased morbidity from viral lower respiratory tract infections because of underlying anatomical cardiac lesions. There are limited data on the implications of COVID-19 on patients with cardiovascular disease, especially for those with CHD. Herein, we aimed to summarise the COVID-19-specific perioperative management issues for newborns with CHD by combining available data from the perspectives of neonatology and paediatric cardiovascular surgery.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Heart Defects, Congenital/surgery ; Humans ; Infant, Newborn ; Pandemics/prevention & control ; Perioperative Care ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 1078466-4
    ISSN 1467-1107 ; 1047-9511
    ISSN (online) 1467-1107
    ISSN 1047-9511
    DOI 10.1017/S1047951120001845
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Clinical Presentation and Successful Management of an Infant With Down Syndrome and COVID-19 in Riyadh, Saudi Arabia.

    Alsahabi, Ibrahim / Alobaidi, Abdulaziz / Alahmari, Ayman S / Almohsen, Noof / Alhamoud, Abdullah H

    Cureus

    2021  Volume 13, Issue 2, Page(s) e13188

    Abstract: ... on the reported case, infants with DS and CHD should be considered a high-risk patient in terms of COVID-19 ... we report the first case of COVID-19 in a four-month-old infant girl with DS and congenital heart disease ... that children with DS are at risk of developing a severe case of COVID-19 if the virus is contracted. Here ...

    Abstract Coronavirus is a serious, global disease. Down syndrome (DS) is characterized by immune dysregulation, has various anatomical variations, and is considered as comorbidity. These variations mean that children with DS are at risk of developing a severe case of COVID-19 if the virus is contracted. Here, we report the first case of COVID-19 in a four-month-old infant girl with DS and congenital heart disease (CHD) who was treated in Al-Imam Abdulrahman Al Faisal Hospital in the first health cluster in Riyadh, Saudi Arabia. The medical management and clinical outcome of the infant are reviewed. The infant was admitted after having received previous treatment from other hospitals, with a deteriorating condition. The patient had developed a rash, and oxygen support was required in addition to her baseline medication (furosemide and captopril). Ten days post admission, the patient's condition improved, and she became clinically stable. She was then discharged after two consecutive negative nasopharyngeal swabs. Based on the reported case, infants with DS and CHD should be considered a high-risk patient in terms of COVID-19 infection and require close observation.
    Language English
    Publishing date 2021-02-07
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.13188
    Database MEDical Literature Analysis and Retrieval System OnLINE

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