Article: Dementia as Risk Factor for Severe Coronavirus Disease 2019: A Case-Control Study.
Frontiers in aging neuroscience
2021 Volume 13, Page(s) 698184
Abstract: ... matched case-control study all 23 patients with a history of dementia, hospitalized with a diagnosis of SARS-CoV-2 infection ... Patients with dementia are vulnerable and have an increased risk of a severe disease and death ... the patients in the Case group less frequently had a moderate disease of COVID-19 (35 vs. 67.4%, : Conclusion ...
| Abstract | Background: The aim of the present study was to investigate the outcome of patients with SARS-CoV-2 infection and dementia. Patients and methods: In a multicenter, observational, 1:2 matched case-control study all 23 patients with a history of dementia, hospitalized with a diagnosis of SARS-CoV-2 infection from February 28th 2020 to January 31st 2021 were enrolled. For each Case, 2 patients without dementia observed in the same period study, pair matched for gender, age (±5 years), PaO Results: The majority of patients were males (60.9% of Cases and Controls) and very elderly [median age 82 years (IQR: 75.5-85) in the Cases and 80 (IQR: 75.5-83.75) in the Controls]. The prevalence of co-pathologies was very high: all the Cases and 43 (93.5%) Controls showed a Charlson comorbidity index of at least 2. During hospitalization the patients in the Case group less frequently had a moderate disease of COVID-19 (35 vs. 67.4%, Conclusion: Patients with dementia are vulnerable and have an increased risk of a severe disease and death when infected with COVID-19. |
|---|---|
| Language | English |
| Publishing date | 2021-06-29 |
| Publishing country | Switzerland |
| Document type | Journal Article |
| ZDB-ID | 2558898-9 |
| ISSN | 1663-4365 |
| ISSN | 1663-4365 |
| DOI | 10.3389/fnagi.2021.698184 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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