Article ; Online: Nuclear Imaging of Bacterial Infection: The State of the Art and Future Directions.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
2020 Volume 61, Issue 12, Page(s) 1708–1716
Abstract: ... functional imaging techniques used for the diagnosis of bacterial infection and their roles in different ... to achieve. Structural imaging techniques such as CT and MRI are often applied to this problem ... of infectious pathophysiology beyond morphologic imaging. This review will discuss the current structural and ...
| Abstract | Increased mortality rates from infectious diseases is a growing public health concern. Successful management of acute bacterial infections requires early diagnosis and treatment, which are not always easy to achieve. Structural imaging techniques such as CT and MRI are often applied to this problem. However, these methods generally rely on secondary inflammatory changes and are frequently not specific to infection. The use of nuclear medicine techniques can add crucial complementary information, allowing visualization of infectious pathophysiology beyond morphologic imaging. This review will discuss the current structural and functional imaging techniques used for the diagnosis of bacterial infection and their roles in different clinical scenarios. We will also present several new radiotracers in development, with an emphasis on probes targeting bacteria-specific metabolism. As highlighted by the current coronavirus disease 2019 epidemic, caused by the novel severe acute respiratory syndrome coronavirus 2, similar thinking may apply in imaging viral pathogens; for this case, prominent effects on host proteins, most notably angiotensin-converting enzyme 2, might also provide worthwhile imaging targets. |
|---|---|
| MeSH term(s) | Animals ; Bacterial Infections/diagnostic imaging ; Bacterial Infections/drug therapy ; Diagnostic Imaging/methods ; Humans ; Nuclear Medicine/methods |
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-08-06 |
| Publishing country | United States |
| Document type | Journal Article ; Review |
| ZDB-ID | 80272-4 |
| ISSN | 1535-5667 ; 0097-9058 ; 0161-5505 ; 0022-3123 |
| ISSN (online) | 1535-5667 |
| ISSN | 0097-9058 ; 0161-5505 ; 0022-3123 |
| DOI | 10.2967/jnumed.120.244939 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
| Zs.A 114: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
|||
| Zs.MO 328: Show issues |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.