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  1. Article ; Online: SARS-CoV-2 -RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients'; an observational study.

    Prakash, Shantanu / Shukla, Suruchi / Mishra, Hricha / Prakash, Om / Khan, Danish N / Pandey, Ajay / Reddy, D Himanshu / Jain, Amita

    Indian journal of medical microbiology

    2020  Volume 39, Issue 1, Page(s) 122–124

    Abstract: ... RNA was detected in nasal swab (NS), throat swab (TS) and faecal sample but was not detected in serum ... to find out SARS-CoV-RNA shedding in various clinical samples of 9 COVID-19 positive patients. SARS-CoV ... and urine samples. We also report that SARS-CoV-2-RNA persisted in faeces for >20 days. Persistence ...

    Abstract The route of transmission of Novel SARS-CoV-2 virus is ambiguous. In this regard we planned a study to find out SARS-CoV-RNA shedding in various clinical samples of 9 COVID-19 positive patients. SARS-CoV-RNA was detected in nasal swab (NS), throat swab (TS) and faecal sample but was not detected in serum and urine samples. We also report that SARS-CoV-2-RNA persisted in faeces for >20 days. Persistence of faecal RNA might impose challenge in infection control and the disease may spread to household contacts if discharged. Perineal cleaning and hygiene may be advised at the time of vaginal delivery.
    MeSH term(s) Adolescent ; Adult ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/virology ; Child ; Child, Preschool ; Feces/virology ; Female ; Humans ; Male ; Middle Aged ; Nasal Cavity/virology ; Pharynx/virology ; RNA, Viral ; SARS-CoV-2 ; Time Factors ; Viral Load ; Young Adult
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2020-11-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1038798-5
    ISSN 1998-3646 ; 0255-0857
    ISSN (online) 1998-3646
    ISSN 0255-0857
    DOI 10.1016/j.ijmmb.2020.10.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: SARS-CoV-2RNA Persists Longer in Faecal Sample as Compared to Nasal and Throat Swab Samples Of COVID-19 Patients’; An Observational Study

    Prakash, Shantanu / Shukla, Suruchi / Mishra, Hricha / Prakash, Om / Khan, Danish N. / Pandey, Ajay / Reddy, D. Himanshu / Jain, Amita

    Indian J Med Microbiol

    Abstract: ... if discharged. Thus, COVID-19 Patients showing RNA clearance from nasal and throat swab sample should be advised ... it for four weeks. RESULTS: SARS-CoV-RNA was detected in nasal swab (NS), throat swab (TS) and faecal sample ... pattern in various clinical samples of COVID-19 patients. METHODS: & Material: We studied nine SARS CoV-2 ...

    Abstract AIMS: Little known about five months old Coronavirus also called as SARS-CoV-2; causing pandemic and health crises worldwide. As the current literature documents, the presence of SARS-CoV-RNA in pulmonary and extra-pulmonary clinical samples such as blood, urine and faeces, but still the route of transmission of this new COVID-19 virus is ambiguous. SETTING: & Design: To study the SARS-CoV-RNA shedding pattern in various clinical samples of COVID-19 patients. METHODS: & Material: We studied nine SARS CoV-2-RNA positive cases admitted in tertiary care hospital of Uttar Pradesh, North India and followed it for four weeks. RESULTS: SARS-CoV-RNA was detected in nasal swab (NS), throat swab (TS) and faecal sample but was not detected in serum and urine samples. The trend of clearance of SARS-CoV-2-RNA from clinical samples was first from throat swab, than nasal swab and last from stool sample. CONCLUSIONS: Persistence of faecal RNA might impose challenge in infection control and the disease may spread by household contacts if discharged. Thus, COVID-19 Patients showing RNA clearance from nasal and throat swab sample should be advised strictly to follow personal hygiene precautions. Perineal cleaning and hygiene may be advised at the time of vaginal delivery.
    Keywords covid19
    Publisher Elsevier; PMC
    Document type Article ; Online
    DOI 10.1016/j.ijmmb.2020.10.012
    Database COVID19

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