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  1. Article ; Online: Delirium and Mortality in Coronavirus Disease 2019 (COVID-19) - A Systematic Review and Meta-analysis.

    Pranata, Raymond / Huang, Ian / Lim, Michael Anthonius / Yonas, Emir / Vania, Rachel / Kuswardhani, Raden Ayu Tuty

    Archives of gerontology and geriatrics

    2021  Volume 95, Page(s) 104388

    Abstract: Introduction: Older adults are indisputably struck hard by the coronavirus disease 2019 (COVID-19 ... mortality in older adults with COVID-19.: Methods: Systematic literature searches of PubMed, Embase, and ... patients from 9 studies were included in this systematic review and meta-analysis. The percentage ...

    Abstract Introduction: Older adults are indisputably struck hard by the coronavirus disease 2019 (COVID-19) pandemic. The main objective of this meta-analysis is to establish the association between delirium and mortality in older adults with COVID-19.
    Methods: Systematic literature searches of PubMed, Embase, and Scopus databases were performed up until 28 November 2020. The exposure in this study was the diagnosis of delirium using clinically validated criteria. Delirium might be in-hospital, at admission, or both. The main outcome was mortality defined as clinically validated non-survivor/death. The effect estimates were reported as odds ratios (ORs) and adjusted odds ratios (aORs).
    Results: A total of 3,868 patients from 9 studies were included in this systematic review and meta-analysis. The percentage of patients with delirium was 27% [20%, 34%]. Every 1 mg/L increase in CRP was significantly associated with 1% increased delirium risk (OR 1.01 [1.00. 1.02], p=0.033). Delirium was associated with mortality (OR 2.39 [1.64, 3.49], p<0.001; I
    Conclusion: The presence of delirium is associated with increased risk of mortality in hospitalized older adults with COVID-19.
    MeSH term(s) Aged ; COVID-19 ; Delirium/diagnosis ; Delirium/epidemiology ; Humans ; Hypertension/epidemiology ; Male ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2021-03-05
    Publishing country Netherlands
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 603162-6
    ISSN 1872-6976 ; 0167-4943
    ISSN (online) 1872-6976
    ISSN 0167-4943
    DOI 10.1016/j.archger.2021.104388
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1729: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Prevalence, incidence and mortality of delirium in patients with COVID-19: a systematic review and meta-analysis.

    Shao, Shih-Chieh / Lai, Chien-Cheng / Chen, Yi-Hung / Chen, Yung-Chang / Hung, Ming-Jui / Liao, Shu-Chen

    Age and ageing

    2021  Volume 50, Issue 5, Page(s) 1445–1453

    Abstract: Background: Attention should be paid to delirium in coronavirus disease 2019 (COVID-19) patients ... and mortality rates for delirium in COVID-19 patients were 28.2% (95% CI: 23.5-33.1%), 25.2% (95% CI ... incidence and mortality rates for delirium in COVID-19 patients were 15.7% (95% CI: 9.2-23.6%), 71.4% (95 ...

    Abstract Background: Attention should be paid to delirium in coronavirus disease 2019 (COVID-19) patients, especially older people, since advanced age poses increased risk of both delirium and COVID-19-related death.
    Objective: This study aims to summarise the evidence on prevalence, incidence and mortality of delirium in COVID-19 patients.
    Methods: We conducted a comprehensive literature search on Pubmed and Embase from inception to 1 December 2020. Three independent reviewers evaluated study eligibility and data extraction, and assessed study quality. Outcomes were analysed as proportions with 95% confidence interval (CI). We also compared mortality differences in COVID-19 patients using odds ratio.
    Results: In total, we identified 48 studies with 11,553 COVID-19 patients from 13 countries. Pooled prevalence, incidence and mortality rates for delirium in COVID-19 patients were 24.3% (95% CI: 19.4-29.6%), 32.4% (95% CI: 20.8-45.2%) and 44.5% (95% CI: 36.1-53.0%), respectively. For patients aged over 65 years, prevalence, incidence and mortality rates for delirium in COVID-19 patients were 28.2% (95% CI: 23.5-33.1%), 25.2% (95% CI: 16.0-35.6%) and 48.4% (95% CI: 40.6-56.1%), respectively. For patients under 65 years, prevalence, incidence and mortality rates for delirium in COVID-19 patients were 15.7% (95% CI: 9.2-23.6%), 71.4% (95% CI: 58.5-82.7%) and 21.2% (95% CI: 15.4-27.6%), respectively. Overall, COVID-19 patients with delirium suffered higher risk of mortality, compared with those without delirium (OR: 3.2, 95% CI: 2.1-4.8).
    Conclusion: Delirium developed in almost 1 out of 3 COVID-19 patients, and was associated with 3-fold overall mortality. Our findings suggest that first-line healthcare providers should systematically assess delirium and monitor related symptoms among COVID-19 patients.
    MeSH term(s) Aged ; COVID-19 ; Delirium/diagnosis ; Delirium/epidemiology ; Humans ; Incidence ; Middle Aged ; Prevalence ; SARS-CoV-2
    Language English
    Publishing date 2021-05-13
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 186788-x
    ISSN 1468-2834 ; 0002-0729
    ISSN (online) 1468-2834
    ISSN 0002-0729
    DOI 10.1093/ageing/afab103
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 877: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 448: Show issues

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  3. Article ; Online: Delirium is a good predictor for poor outcomes from coronavirus disease 2019 (COVID-19) pneumonia: A systematic review, meta-analysis, and meta-regression.

    Hariyanto, Timotius Ivan / Putri, Cynthia / Hananto, Joshua Edward / Arisa, Jessie / Fransisca V Situmeang, Rocksy / Kurniawan, Andree

    Journal of psychiatric research

    2021  Volume 142, Page(s) 361–368

    Abstract: ... delirium and poor outcomes from COVID-19.: Methods: We systematically searched the PubMed and Google ... published on COVID-19 and delirium were retrieved. The quality of the study was assessed using the Newcastle ... with delirium may have a higher morbidity and mortality rate due to older age, other comorbidities, and atypical ...

    Abstract Aim: Delirium is a common presenting symptom among older patients. Patients who presented with delirium may have a higher morbidity and mortality rate due to older age, other comorbidities, and atypical COVID-19 presentation. Currently, the evidence supporting delirium as one of the predictors of poor outcome of COVID-19 is still insufficient. This study aims to explore the potential association between delirium and poor outcomes from COVID-19.
    Methods: We systematically searched the PubMed and Google Scholar databases using specific keywords related to our aims until January 30th, 2021. All articles published on COVID-19 and delirium were retrieved. The quality of the study was assessed using the Newcastle Ottawa Scale (NOS) tool for observational studies and Joanna Briggs Institute (JBI) Critical Appraisal Tools for case-series studies. Statistical analysis was done using Review Manager 5.4 software.
    Results: Our meta-analysis of 20 studies showed that delirium symptoms on admission was associated with poor outcomes from COVID-19 [OR 2.36 (95% CI 1.80-3.09), p < 0.00001, I
    Conclusions: Our study suggests delirium as an important marker to identify patients at higher risk for developing poor COVID-19 outcomes. The physicians should add delirium as one of the common presenting symptoms of COVID-19 in older populations.
    MeSH term(s) Aged ; COVID-19 ; Comorbidity ; Delirium/diagnosis ; Delirium/epidemiology ; Humans ; Pneumonia/complications ; Pneumonia/epidemiology ; SARS-CoV-2
    Language English
    Publishing date 2021-08-20
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 3148-3
    ISSN 1879-1379 ; 0022-3956
    ISSN (online) 1879-1379
    ISSN 0022-3956
    DOI 10.1016/j.jpsychires.2021.08.031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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