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Article ; Online: Out-of-hospital cardiac arrest prognosis during the COVID-19 pandemic.

Pranata, Raymond / Lim, Michael Anthonius / Yonas, Emir / Siswanto, Bambang Budi / Meyer, Markus

2020 Volume 15, Issue 5, Page(s) 875–877

MeSH term(s)	Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Out-of-Hospital Cardiac Arrest ; Pandemics ; Pneumonia, Viral ; Prognosis ; SARS-CoV-2 ; ST Elevation Myocardial Infarction
Keywords	covid19
Language	English
Publishing date	2020-07-09
Publishing country	Italy
Document type	Letter ; Comment
ZDB-ID	2454173-4
ISSN	1970-9366 ; 1828-0447
ISSN (online)	1970-9366
ISSN	1828-0447
DOI	10.1007/s11739-020-02428-7
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Article: Out-of-hospital cardiac arrest prognosis during the COVID-19 pandemic

Pranata, Raymond / Lim, Michael Anthonius / Yonas, Emir / Siswanto, Bambang Budi / Meyer, Markus

Intern Emerg Med

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #637453
Database	COVID19

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Article ; Online: Out-of-hospital cardiac arrest prognosis during the COVID-19 pandemic

Pranata, Raymond / Lim, Michael Anthonius / Yonas, Emir / Siswanto, Bambang Budi / Meyer, Markus

Internal and Emergency Medicine

2020 Volume 15, Issue 5, Page(s) 875–877

Keywords	Internal Medicine ; Emergency Medicine ; covid19
Language	English
Publisher	Springer Science and Business Media LLC
Publishing country	us
Document type	Article ; Online
ZDB-ID	2454173-4
ISSN	1970-9366 ; 1828-0447
ISSN (online)	1970-9366
ISSN	1828-0447
DOI	10.1007/s11739-020-02428-7
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Impact of the COVID-19 pandemic on prehospital and in-hospital treatment and outcomes of patients after out-of-hospital cardiac arrest: a Japanese multicenter cohort study.

Tanaka, Chie / Tagami, Takashi / Kaneko, Junya / Kitamura, Nobuya / Yasunaga, Hideo / Aso, Shotaro / Takeda, Munekazu / Kuno, Masamune

BMC emergency medicine

2024 Volume 24, Issue 1, Page(s) 12

Abstract: ... of care contributes to improve the prognosis of the patient with OHCA. The SARS-CoV-2 (COVID-19) pandemic ... Background: In the chain of survival for Out-of-hospital cardiac arrest (OHCA), each component ... prehospital care, in-hospital treatment, and outcomes among OHCA patients before and after the COVID-19 ...

Abstract	Background: In the chain of survival for Out-of-hospital cardiac arrest (OHCA), each component of care contributes to improve the prognosis of the patient with OHCA. The SARS-CoV-2 (COVID-19) pandemic potentially affected each part of care in the chain of survival. The aim of this study was to compare prehospital care, in-hospital treatment, and outcomes among OHCA patients before and after the COVID-19 pandemic. Methods: We analyzed data from a multicenter prospective study in Kanto area, Japan, named SOS-KANTO 2017. We enrolled patients who registered during the pre-pandemic period (September 2019 to December 2019) and the post-pandemic period (June 2020 to March 2021). The main outcome measures were 30-day mortality and the proportion of favorable outcomes at 1 month, and secondary outcome measures were changes in prehospital and in-hospital treatments between the pre- and post-pandemic periods. Results: There were 2015 patients in the pre-pandemic group, and 5023 in the post-pandemic group. The proportion of advanced airway management by emergency medical service (EMS) increased (p < 0.01), and EMS call-to-hospital time was prolonged (p < 0.01) in the post- versus pre-pandemic group. There were no differences between the groups in defibrillation, extracorporeal membrane oxygenation, or temperature control therapy (p = 0.43, p = 0.14, and p = 0.16, respectively). Survival rate at 1 month and favorable outcome rate at 1 month were lower (p = 0.01 and p < 0.01, respectively) in the post- versus pre-pandemic group. Conclusion: Survival rate and favorable outcome rate 1 month after return of spontaneous circulation of OHCA worsened, EMS response time was prolonged, and advanced airway management by EMS increased in the post- versus pre-pandemic group; however, most prehospital and in-hospital management did not change between pre- and post-COVID-19 pandemic.
MeSH term(s)	Humans ; Japan/epidemiology ; Pandemics ; COVID-19/epidemiology ; Out-of-Hospital Cardiac Arrest/epidemiology ; Out-of-Hospital Cardiac Arrest/therapy ; Prospective Studies ; SARS-CoV-2 ; Hospitals ; Emergency Medical Services ; Treatment Outcome
Language	English
Publishing date	2024-01-08
Publishing country	England
Document type	Multicenter Study ; Journal Article
ZDB-ID	2050431-7
ISSN	1471-227X ; 1471-227X
ISSN (online)	1471-227X
ISSN	1471-227X
DOI	10.1186/s12873-024-00929-8
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Article ; Online: Comparison of out-of-hospital cardiac arrests during the COVID-19 pandemic with those before the pandemic: an updated systematic review and meta-analysis.

Kim, Jae Hwan / Ahn, Chiwon / Park, Yeonkyung / Won, Moonho

Frontiers in public health

2023 Volume 11, Page(s) 1180511

Abstract: ... the OHCA outcomes and epidemiological characteristics during the COVID-19 pandemic with before the pandemic ... During the COVID-19 pandemic, survival and favorable neurological outcome rates were significantly lower ... The COVID-19 pandemic altered the epidemiologic characteristics, survival rates, and neurological prognosis ...

Abstract	The coronavirus disease of 2019 (COVID-19) pandemic, directly and indirectly, affected the emergency medical care system and resulted in worse out-of-hospital cardiac arrest (OHCA) outcomes and epidemiological features compared with those before the pandemic. This review compares the regional and temporal features of OHCA prognosis and epidemiological characteristics. Various databases were searched to compare the OHCA outcomes and epidemiological characteristics during the COVID-19 pandemic with before the pandemic. During the COVID-19 pandemic, survival and favorable neurological outcome rates were significantly lower than before. Survival to hospitalization, return of spontaneous circulation, endotracheal intubation, and use of an automated external defibrillator (AED) decreased significantly, whereas the use of a supraglottic airway device, the incidence of cardiac arrest at home, and response time of emergency medical service (EMS) increased significantly. Bystander CPR, unwitnessed cardiac arrest, EMS transfer time, use of mechanical CPR, and in-hospital target temperature management did not differ significantly. A subgroup analysis of the studies that included only the first wave with those that included the subsequent waves revealed the overall outcomes in which the epidemiological features of OHCA exhibited similar patterns. No significant regional differences between the OHCA survival rates in Asia before and during the pandemic were observed, although other variables varied by region. The COVID-19 pandemic altered the epidemiologic characteristics, survival rates, and neurological prognosis of OHCA patients.
MeSH term(s)	Humans ; Cardiopulmonary Resuscitation/adverse effects ; Cardiopulmonary Resuscitation/methods ; Pandemics ; COVID-19/epidemiology ; COVID-19/complications ; Out-of-Hospital Cardiac Arrest/epidemiology ; Out-of-Hospital Cardiac Arrest/therapy ; Out-of-Hospital Cardiac Arrest/etiology ; Emergency Medical Services
Language	English
Publishing date	2023-05-04
Publishing country	Switzerland
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2023.1180511
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Article: Impact of Coronavirus Disease 2019 Pandemic on Pediatric Out-of-Hospital Cardiac Arrest in the Emergency Department.

Chen, Chun-Yu / Lee, En-Pei / Chang, Yu-Jun / Yang, Wen-Chieh / Lin, Mao-Jen / Wu, Han-Ping

Frontiers in pediatrics

2022 Volume 10, Page(s) 846410

Abstract: ... prognosis. After the coronavirus disease 2019 (COVID-19) pandemic developed, the epidemiology and clinical ... Background: Out-of-hospital cardiac arrest (OHCA) in children is a critical condition with a poor ... the impact of the COVID-19 pandemic on pediatric OHCA in the PED.: Methods: From January 2018 to September ...

Abstract	Background: Out-of-hospital cardiac arrest (OHCA) in children is a critical condition with a poor prognosis. After the coronavirus disease 2019 (COVID-19) pandemic developed, the epidemiology and clinical characteristics of the pediatric emergency department (PED) visits have changed. This study aimed to analyze the impact of the COVID-19 pandemic on pediatric OHCA in the PED. Methods: From January 2018 to September 2021, we retrospectively collected data of children (18 years or younger) with a definite diagnosis of OHCA admitted to the PED. Patient data studied included demographics, pre-/in-hospital information, treatment modalities; and outcomes of interest included sustained return of spontaneous circulation (SROSC) and survival to hospital-discharge (STHD). These were analyzed and compared between the periods before and after the COVID-19 pandemic. Results: A total of 97 patients with OHCA (68 boys and 29 girls) sent to the PED were enrolled in our study. Sixty cases (61.9%) occurred in the pre-pandemic period and 37 during the pandemic. The most common age group was infants (40.2%) ( Conclusion: During the COVID-19 pandemic, children with OHCA had a significantly lower rate of SROSC and STHD than that in the pre-pandemic period. The COVID-19 pandemic has changed the nature of PED visits and has affected factors related to ROSC and STHD in pediatric OHCA.
Language	English
Publishing date	2022-04-25
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2711999-3
ISSN	2296-2360
ISSN	2296-2360
DOI	10.3389/fped.2022.846410
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Article ; Online: Association between the COVID-19 pandemic in 2020 and out-of-hospital cardiac arrest outcomes and bystander resuscitation efforts for working-age individuals in Japan: a nationwide observational and epidemiological analysis.

Ushimoto, Tomoyuki / Yao, Shintaro / Nunokawa, Chika / Murasaka, Kenshi / Inaba, Hideo

Emergency medicine journal : EMJ

2023 Volume 40, Issue 8, Page(s) 556–563

Abstract: Background: Improving out-of-hospital cardiac arrest (OHCA) prognosis within the working-age ... population is important, but no studies have investigated the effects of COVID-19 pandemic specifically ... on the working-age population with OHCAs. We aimed to determine the association between the 2020 COVID-19 ...

Abstract	Background: Improving out-of-hospital cardiac arrest (OHCA) prognosis within the working-age population is important, but no studies have investigated the effects of COVID-19 pandemic specifically on the working-age population with OHCAs. We aimed to determine the association between the 2020 COVID-19 pandemic and OHCA outcomes and bystander resuscitation efforts among the working-age population. Methods: Prospectively collected nationwide, population-based records concerning 166 538 working-age individuals (men, 20-68 years; women, 20-62 years) with OHCA between 2017 and 2020 were assessed. We compared characteristics and outcome differences of the arrests between three prepandemic years (2017-2019) and the pandemic year 2020. The primary outcome was neurologically favourable 1-month survival (cerebral performance category 1 or 2). Secondary outcomes were bystander cardiopulmonary resuscitation (BCPR), dispatcher-assisted instruction for cardiopulmonary resuscitation (DAI-CPR), bystander-provided defibrillation (public access defibrillation (PAD)) and 1-month survival. We examined variations in bystander resuscitation efforts and outcomes among pandemic phase and regional classifications. Results: Among 149 300 OHCA cases, 1-month survival (2020, 11.2%; 2017-2019, 11.1% (crude OR (cOR) 1.00, 95% CI 0.97 to 1.05)) and 1-month neurologically favourable survival (7.3%-7.3% (cOR 1.00, 95% CI 0.96 to 1.05)) were unchanged; however, the neurologically favourable 1-month survival rate decreased in 12 of the most COVID-19-affected prefectures (7.2%-7.8% (cOR 0.90, 95% CI 0.85 to 0.96)), whereas it increased in 35 other prefectures (7.5%-6.6% (cOR 1.15, 95% CI 1.07 to 1.23)). Favourable outcomes decreased for OHCAs of presumed cardiac aetiology (10.3%-10.9% (cOR 0.94, 95% CI 0.90 to 0.99)) but increased for OHCAs of non-cardiac aetiology (2.5%-2.0% (cOR 1.27, 95% CI 1.12 to 1.44)). BCPR provision increased from 50.7% of arrests prepandemic to 52.3% (crude OR 1.07, 95% CI 1.04 to 1.09). Compared with 2017-2019, home-based OHCAs in 2020 increased (64.8% vs 62.3% (crude OR 1.12, 95% CI 1.09 to 1.14)), along with DAI-CPR attempts (59.5% vs 56.6% (cOR 1.13, 95% CI 1.10 to 1.15)) and multiple calls to determine a destination hospital (16.4% vs 14.5% (cOR 1.16, 95% CI 1.12 to 1.20)). PAD use decreased from 4.0% to 3.7% but only during the state of emergency period (7 April-24 May 2020) and in prefectures significantly affected by COVID-19. Conclusions: Reviewing automated external defibrillator (AED) locations and increasing BCPR through DAI-CPR may help prevent pandemic-associated decreases in survival rates for patients with cardiac OHCAs.
MeSH term(s)	Male ; Humans ; Female ; Young Adult ; Adult ; Middle Aged ; Aged ; Pandemics ; Japan/epidemiology ; Out-of-Hospital Cardiac Arrest/epidemiology ; Out-of-Hospital Cardiac Arrest/therapy ; COVID-19/epidemiology ; Cardiopulmonary Resuscitation
Language	English
Publishing date	2023-06-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2040124-3
ISSN	1472-0213 ; 1472-0205
ISSN (online)	1472-0213
ISSN	1472-0205
DOI	10.1136/emermed-2022-213001
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Article ; Online: The Influence of COVID-19 on Out-Hospital Cardiac Arrest Survival Outcomes

Karol Bielski / Agnieszka Szarpak / Miłosz Jaroslaw Jaguszewski / Tomasz Kopiec / Jacek Smereka / Aleksandra Gasecka / Przemysław Wolak / Grazyna Nowak-Starz / Jaroslaw Chmielewski / Zubaid Rafique / Frank William Peacock / Lukasz Szarpak

Journal of Clinical Medicine, Vol 10, Iss 5573, p

An Updated Systematic Review and Meta-Analysis

2021 Volume 5573

Abstract: ... p = 0.009). In conclusion, prognosis of OHCA is usually poor and even worse during COVID-19. ... with poor prognosis. Because the COVID-19 pandemic may have impacted mortality and morbidity ... Cardiopulmonary resuscitation in patients with out-of-hospital cardiac arrest (OHCA) is associated ...

Abstract	Cardiopulmonary resuscitation in patients with out-of-hospital cardiac arrest (OHCA) is associated with poor prognosis. Because the COVID-19 pandemic may have impacted mortality and morbidity, both on an individual level and the health care system as a whole, our purpose was to determine rates of OHCA survival since the onset of the SARS-CoV2 pandemic. We conducted a systematic review and meta-analysis to evaluate the influence of COVID-19 on OHCA survival outcomes according to the PRISMA guidelines. We searched the literature using PubMed, Scopus, Web of Science and Cochrane Central Register for Controlled Trials databases from inception to September 2021 and identified 1775 potentially relevant studies, of which thirty-one articles totaling 88,188 patients were included in this meta-analysis. Prehospital return of spontaneous circulation (ROSC) in pre-COVID-19 and COVID-19 periods was 12.3% vs. 8.9%, respectively (OR = 1.40; 95%CI: 1.06–1.87; p < 0.001). Survival to hospital discharge in pre- vs. intra-COVID-19 periods was 11.5% vs. 8.2% (OR = 1.57; 95%CI: 1.37–1.79; p < 0.001). A similar dependency was observed in the case of survival to hospital discharge with the Cerebral Performance Category (CPC) 1–2 (6.7% vs. 4.0%; OR = 1.71; 95%CI: 1.35–2.15; p < 0.001), as well as in the 30-day survival rate (9.2% vs. 6.4%; OR = 1.63; 95%CI: 1.13–2.36; p = 0.009). In conclusion, prognosis of OHCA is usually poor and even worse during COVID-19.
Keywords	SARS-CoV-2 ; cardiopulmonary resuscitation ; coronavirus disease 2019 ; out-of-hospital cardiac arrest ; outcome ; pandemic ; Medicine ; R
Subject code	360
Language	English
Publishing date	2021-11-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: Out-of-hospital cardiac arrest treated by emergency medical service teams during COVID-19 pandemic: A retrospective cohort study.

Borkowska, Magdalena J / Smereka, Jacek / Safiejko, Kamil / Nadolny, Klaudiusz / Maslanka, Maciej / Filipiak, Krzysztof J / Jaguszewski, Milosz J / Szarpak, Lukasz

Cardiology journal

2020 Volume 28, Issue 1, Page(s) 15–22

Abstract: Background: Out-of-hospital cardiac arrest (OHCA) is a challenge for medical personnel, especially ... in the current COVID-19 pandemic, where medical personnel should perform resuscitation wearing full ... an OHCA in the COVID-19 pandemic treated by emergency medical service (EMS) teams.: Methods: All EMS ...

Abstract	Background: Out-of-hospital cardiac arrest (OHCA) is a challenge for medical personnel, especially in the current COVID-19 pandemic, where medical personnel should perform resuscitation wearing full personal protective equipment. This study aims were to assess the characteristics and outcomes of adults who suffered an OHCA in the COVID-19 pandemic treated by emergency medical service (EMS) teams. Methods: All EMS-attended OHCA adults over than 18 years in the Polish EMS registry were analyzed. The retrospective EMS database was conducted. EMS interventions performed between March 1, and April 30, 2020 were retrospectively screened. Results: In the study period EMS operated 527 times for OHCA cases. The average age of patients with OHCA was 67.8 years. Statistically significantly more frequently men were involved (64.3%). 298 (56.6%) of all OHCA patients had resuscitation attempted by EMS providers. Among resuscitated patients, 73.8% were cardiac etiology. 9.4% of patients had return of spontaneous circulation, 27.2% of patients were admitted to hospital with ongoing chest compression. In the case of 63.4% cardiopulmonary resuscitation was ineffective and death was determined. Conclusions: The present study found that OHCA incidence rate in the Masovian population (central region of Poland) in March-April 2020 period was 12.2/100,000 adult inhabitants. Return of spontaneous circulation in EMS was observed only in 9.4% of resuscitated patients. The presence of shockable rhythms was associated with better prognosis. The prehospital mortality, even though it was high, did not differ from those reported by other studies.
MeSH term(s)	Aged ; Aged, 80 and over ; COVID-19/epidemiology ; Cardiopulmonary Resuscitation/methods ; Cause of Death/trends ; Emergency Medical Services/statistics & numerical data ; Female ; Follow-Up Studies ; Humans ; Incidence ; Italy/epidemiology ; Male ; Out-of-Hospital Cardiac Arrest/epidemiology ; Out-of-Hospital Cardiac Arrest/therapy ; Pandemics ; Prognosis ; Registries ; Retrospective Studies ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-11-03
Publishing country	Poland
Document type	Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
ZDB-ID	2488680-4
ISSN	1897-5593 ; 1897-5593
ISSN (online)	1897-5593
ISSN	1897-5593
DOI	10.5603/CJ.a2020.0135
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Article: Tree-Based Algorithms and Association Rule Mining for Predicting Patients' Neurological Outcomes After First-Aid Treatment for an Out-of-Hospital Cardiac Arrest During COVID-19 Pandemic: Application of Data Mining.

Lin, Wei-Chun / Huang, Chien-Hsiung / Chien, Liang-Tien / Tseng, Hsiao-Jung / Ng, Chip-Jin / Hsu, Kuang-Hung / Lin, Chi-Chun / Chien, Cheng-Yu

International journal of general medicine

2022 Volume 15, Page(s) 7395–7405

Abstract: ... as data mining tools to find useful determinants for neurological outcomes in out-of-hospital cardiac ... when encountering OHCA or who had ever ROSC during first-aid would be highly correlated with good CPC prognosis ... in overall accuracy (91.19%), weighted precision (88.76%), weighted recall (91.20%) and F1 score (0.9 ...

Abstract	Objective: The authors performed several tree-based algorithms and an association rules mining as data mining tools to find useful determinants for neurological outcomes in out-of-hospital cardiac arrest (OHCA) patients as well as to assess the effect of the first-aid and basic characteristics in the EMS system. Patients and methods: This was a retrospective cohort study. The outcome was Cerebral Performance Categories grading on OHCA patients at hospital discharge. Decision tree-based models inclusive of C4.5 algorithm, classification and regression tree and random forest were built to determine an OHCA patient's prognosis. Association rules mining was another data mining method which we used to find the combination of prognostic factors linked to the outcome. Results: The total of 3520 patients were included in the final analysis. The mean age was 67.53 (±18.4) year-old and 63.4% were men. To overcome the imbalance outcome issue in machine learning, the random forest has a better predictive ability for OHCA patients in overall accuracy (91.19%), weighted precision (88.76%), weighted recall (91.20%) and F1 score (0.9) by oversampling adjustment. Under association rules mining, patients who had any witness on the spot when encountering OHCA or who had ever ROSC during first-aid would be highly correlated with good CPC prognosis. Conclusion: The random forest has a better predictive ability for OHCA patients. This paper provides a role model applying several machine learning algorithms to the first-aid clinical assessment that will be promising combining with Artificial Intelligence for applying to emergency medical services.
Language	English
Publishing date	2022-09-19
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2452220-X
ISSN	1178-7074
ISSN	1178-7074
DOI	10.2147/IJGM.S384959
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