Article: Glycemic Control Improvement in Italian Children and Adolescents With Type 1 Diabetes Followed Through Telemedicine During Lockdown Due to the COVID-19 Pandemic.
2020 Volume 11, Page(s) 595735
Abstract: ... of this study was to evaluate the effects of lockdown on glycemic control in children and adolescents with type ... glycemic control improved during lockdown. Despite patients were confined to their homes and limited ... 1 diabetes (T1D) followed through telemedicine.: Subjects/methods: This observational study ...
| Abstract | Background/objective: To minimize the wide spread of coronavirus disease (COVID-19) pandemic, Italy was placed in an almost complete lockdown state that forced people to "stay at home". Aim of this study was to evaluate the effects of lockdown on glycemic control in children and adolescents with type 1 diabetes (T1D) followed through telemedicine. Subjects/methods: This observational study involved patients with T1D using the real-time continuous glucose monitoring (CGM) Dexcom G6 Results: Sixty-two children and adolescents (11.1 ± 4.37 years, 50% males) with T1D (median time disease 3.67 years) were enrolled in the study. Insulin total daily dose was unchanged, while time spent on physical activities was decreased (p<0.0001). Despite the lack of statistical significance, median value of the glucose management indicator decreased from 7.4% to 7.25%. Glucose standard deviation (p<0.0001) and coefficient of variation (p=0.001) improved across the study. Median time in range increased from 60.5% to 63.5% (p=0.008), time above range decreased from 37.3% to 34.1% (p=0.048), and time below range decreased from 1.85% to 1.45% (p=0.001). Conclusions: Overall, in our children and adolescents with T1D glycemic control improved during lockdown. Despite patients were confined to their homes and limited to exercise, our data suggest that the use of real-time CGM, the continuous parental management, and the telemedicine can display beneficial effects on T1D care. |
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| MeSH term(s) | Adolescent ; Biomarkers/analysis ; Blood Glucose/analysis ; Blood Glucose Self-Monitoring ; COVID-19/complications ; COVID-19/transmission ; COVID-19/virology ; Child ; Diabetes Mellitus, Type 1/drug therapy ; Diabetes Mellitus, Type 1/epidemiology ; Diabetes Mellitus, Type 1/metabolism ; Diabetes Mellitus, Type 1/virology ; Female ; Follow-Up Studies ; Glycemic Control/methods ; Humans ; Hypoglycemic Agents/therapeutic use ; Italy/epidemiology ; Longitudinal Studies ; Male ; Prognosis ; Retrospective Studies ; SARS-CoV-2/isolation & purification ; Telemedicine |
| Chemical Substances | Biomarkers ; Blood Glucose ; Hypoglycemic Agents |
| Language | English |
| Publishing date | 2020-12-07 |
| Publishing country | Switzerland |
| Document type | Journal Article ; Observational Study |
| ZDB-ID | 2592084-4 |
| ISSN | 1664-2392 |
| ISSN | 1664-2392 |
| DOI | 10.3389/fendo.2020.595735 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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