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  1. Article ; Online: Correction: Fluctuations, Correlations and the Estimation of Concentrations inside Cells.

    Pérez Ipiña, Emiliano / Ponce Dawson, Silvina

    PloS one

    2018  Volume 13, Issue 1, Page(s) e0192091

    Abstract: This corrects the article DOI: 10.1371/journal.pone.0151132.]. ...

    Abstract [This corrects the article DOI: 10.1371/journal.pone.0151132.].
    Language English
    Publishing date 2018
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0192091
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Fluctuations, Correlations and the Estimation of Concentrations inside Cells.

    Pérez Ipiña, Emiliano / Ponce Dawson, Silvina

    PloS one

    2016  Volume 11, Issue 3, Page(s) e0151132

    Abstract: ... by individual binding sites. In this paper we study ligand number and site occupancy fluctuations when ligands ... Information transmission in cells occurs quite accurately even when concentration changes are "read ... diffuse and react going beyond the analyses that focus on their asymptotic decay. In this way we show ...

    Abstract Information transmission in cells occurs quite accurately even when concentration changes are "read" by individual binding sites. In this paper we study ligand number and site occupancy fluctuations when ligands diffuse and react going beyond the analyses that focus on their asymptotic decay. In this way we show that, for immobile binding sites, fluctuations in the number of bound molecules decay on a relatively fast scale before the asymptotic behavior kicks in. This result can explain the observed co-existence of highly fluctuating instantaneous transcriptional activities with accumulated mRNA concentrations that have relatively small noise levels. We also show that the initial stages of the decay in the bound molecule number fluctuations have one or two characteristic timescales depending on the concentration of free molecules. This transition can explain the changes in enzyme activity observed at the single molecule level.
    MeSH term(s) Animals ; Drosophila melanogaster ; Models, Biological ; RNA, Messenger/biosynthesis ; Transcription, Genetic/physiology
    Chemical Substances RNA, Messenger
    Language English
    Publishing date 2016-03-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0151132
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Fluctuations, Correlations and the Estimation of Concentrations inside Cells.

    Emiliano Pérez Ipiña / Silvina Ponce Dawson

    PLoS ONE, Vol 11, Iss 3, p e

    2016  Volume 0151132

    Abstract: ... by individual binding sites. In this paper we study ligand number and site occupancy fluctuations when ligands ... Information transmission in cells occurs quite accurately even when concentration changes are "read ... diffuse and react going beyond the analyses that focus on their asymptotic decay. In this way we show ...

    Abstract Information transmission in cells occurs quite accurately even when concentration changes are "read" by individual binding sites. In this paper we study ligand number and site occupancy fluctuations when ligands diffuse and react going beyond the analyses that focus on their asymptotic decay. In this way we show that, for immobile binding sites, fluctuations in the number of bound molecules decay on a relatively fast scale before the asymptotic behavior kicks in. This result can explain the observed co-existence of highly fluctuating instantaneous transcriptional activities with accumulated mRNA concentrations that have relatively small noise levels. We also show that the initial stages of the decay in the bound molecule number fluctuations have one or two characteristic timescales depending on the concentration of free molecules. This transition can explain the changes in enzyme activity observed at the single molecule level.
    Keywords Medicine ; R ; Science ; Q
    Subject code 612
    Language English
    Publishing date 2016-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Correction

    Emiliano Pérez Ipiña / Silvina Ponce Dawson

    PLoS ONE, Vol 13, Iss 1, p e

    Fluctuations, Correlations and the Estimation of Concentrations inside Cells.

    2018  Volume 0192091

    Abstract: This corrects the article DOI:10.1371/journal.pone.0151132.]. ...

    Abstract [This corrects the article DOI:10.1371/journal.pone.0151132.].
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2018-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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