Article ; Online: Low Rate of SARS-CoV-2 Infection in Adults With Active Cancer Diagnosis in a Nonendemic Region in the United States.
WMJ : official publication of the State Medical Society of Wisconsin
2021 Volume 119, Issue 4, Page(s) 286–288
Abstract: ... with an active history of cancer undergoing any elective surgery were screened for SARS-CoV-2 symptoms, including ... Introduction: The mortality rate in cancer patients with SARS-CoV-2 has been cited to be as high ... as 13% amidst a global pandemic. Here we present the prevalence of SARS-CoV-2 in adult patients ...
| Abstract | Introduction: The mortality rate in cancer patients with SARS-CoV-2 has been cited to be as high as 13% amidst a global pandemic. Here we present the prevalence of SARS-CoV-2 in adult patients with active cancer in a nonendemic cancer center at the time of the study. Methods: All adult patients with an active history of cancer undergoing any elective surgery were screened for SARS-CoV-2 symptoms, including fever ≥ 38 degrees Celsius, chills, dyspnea, cough, sputum production, pharyngitis, myalgia/arthralgia, headache, anosmia, and nasal discharge. Both symptomatic and asymptomatic patients were tested for SARS-CoV-2 preoperatively via nasopharyngeal swab within 48 hours of surgery using an RT-PCR assay. Active cancer was defined as receipt of chemotherapy and/or radiation within 1 year of the SARS-CoV-2 test. Deidentified, institutional review board-exempt patient data were analyzed with IBM Statistical Package for the Social Sciences (SPSS) Version 26. Results: Between March 16, 2020 and June 30, 2020, a total of 227 patients were tested preoperatively for SARS-CoV-2. Median age was 64.0 years (range 21 to 90). The majority of the cohort were White. Only 2 patients (0.8%) were positive for SARS-CoV-2. One 73-year-old woman undergoing hip replacement had Stage IV breast cancer and a 75-year-old man undergoing port placement had Stage IV retroperitoneal leiomyosarcoma. Neither patient had symptoms of SARS-CoV-2, underwent hospitalization for SARS-CoV-2, or proceeded to have the scheduled surgery after the positive test results until a 14-day quarantine period and a subsequent negative test result. Both patients subsequently received the procedures they were originally scheduled for with no complications. Conclusion: Careful consideration of resource allocation and treatment limitations for cancer patients should occur in lower endemic regions. |
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| MeSH term(s) | Adult ; Aged ; Aged, 80 and over ; COVID-19/epidemiology ; Female ; Humans ; Male ; Middle Aged ; Neoplasms/epidemiology ; Neoplasms/therapy ; Pandemics ; SARS-CoV-2 ; United States/epidemiology ; Wisconsin/epidemiology | |||||
| Language | English | |||||
| Publishing date | 2021-01-11 | |||||
| Publishing country | United States | |||||
| Document type | Case Reports | |||||
| ZDB-ID | 441051-8 | |||||
| ISSN | 2379-3961 ; 0043-6542 ; 1098-1861 | |||||
| ISSN (online) | 2379-3961 | |||||
| ISSN | 0043-6542 ; 1098-1861 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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