Article ; Online: Making animals alcoholic: shifting laboratory models of addiction.
Journal of the history of the behavioral sciences
2015 Volume 51, Issue 2, Page(s) 164–194
Abstract: The use of animals as experimental organisms has been critical to the development of addiction ... consumption of ethanol to the point of physical dependency. In doing so, we will see how the animal model not ... the processes of addiction that was not available from the study of human subjects. Their use, however, has been ...
Abstract | The use of animals as experimental organisms has been critical to the development of addiction research from the nineteenth century. They have been used as a means of generating reliable data regarding the processes of addiction that was not available from the study of human subjects. Their use, however, has been far from straightforward. Through focusing on the study of alcoholism, where the nonhuman animal proved a most reluctant collaborator, this paper will analyze the ways in which scientists attempted to deal with its determined sobriety and account for their consistent failure to replicate the volitional consumption of ethanol to the point of physical dependency. In doing so, we will see how the animal model not only served as a means of interrogating a complex pathology, but also came to embody competing definitions of alcoholism as a disease process, and alternative visions for the very structure and purpose of a research field. |
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MeSH term(s) | Alcoholism/history ; Animal Experimentation/history ; Animals ; Disease Models, Animal ; History, 20th Century ; Humans ; Mice ; Psychology, Experimental/history ; Rats | |||||
Language | English | |||||
Publishing date | 2015-03-04 | |||||
Publishing country | United States | |||||
Document type | Historical Article ; Journal Article ; Research Support, Non-U.S. Gov't | |||||
ZDB-ID | 6868-8 | |||||
ISSN | 1520-6696 ; 0022-5061 | |||||
ISSN (online) | 1520-6696 | |||||
ISSN | 0022-5061 | |||||
DOI | 10.1002/jhbs.21715 | |||||
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Database | MEDical Literature Analysis and Retrieval System OnLINE |
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